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Лангергансоклеточный гистиоцитоз вульвы: клиническое наблюдение
Лангергансоклеточный гистиоцитоз вульвы: клиническое наблюдение
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Аннотация
В статье представлен клинический случай первичного изолированного злокачественного лангергансоклеточного гистиоцитоза вульвы у больной 33 лет. Показана эффективность гемивульвэктомии в сочетании с адъювантной дистанционной химиолучевой терапией. Ключевое значение в диагностике заболевания имело гистологическое и иммуногистохимическое исследование при адекватном количестве иссеченных тканей. Заболевание требует выработки единых алгоритмов обследования и лечения при мультидисциплинарном подходе.
Ключевые слова: гистиоцитоз X, лангергансоклеточный гистиоцитоз, вульва, лучевая терапия.
Key words: histiocytosis X, Langerhans cell histiocytosis, vulva, radiation therapy.
Ключевые слова: гистиоцитоз X, лангергансоклеточный гистиоцитоз, вульва, лучевая терапия.
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Key words: histiocytosis X, Langerhans cell histiocytosis, vulva, radiation therapy.
Полный текст
Список литературы
1. The Histiocyte Society. URL: http://www.histiocytesociety.org (дата обращения: август 2014 г.).
2. Morimoto A, Oh Y, Shioda Y et al. Recent advances in Langerhans Cell Histiocytosis. Pediatr Int 2014 May 19.
3. El-Safadi S, Dreyer T, Oehmke F, Muenstedt K. Management of adult primary vulvar Langerhans cell histiocytosis: review of the literature and a case history. Eur J Obstet Gynecol Reprod Biol 2012; 163 (2): 123–8.
4. Chang JC, Blake DG, Leung BV, Plaza JA. Langerhans cell histiocytosis associated with lichen sclerosus of the vulva: case report and review of the literature. J Cutan Pathol 2013; 40 (2): 279–83.
5. Foley S, Panting K, Bell H et al. Rapid resolution of primary vulval adult Langerhans cell histiocytosis with very potent topical corticosteroids. Australas J Dermatol 2011; 52 (1): e8–e14.
6. Jiang W(I), Li L, He YM, Yang KX. Langerhans cell histiocytosis of the female genital tract: a literature review with additional three case studies in China. Arch Gynecol Obstet 2012; 285 (1): 99–103.
7. Kurt S, Canda MT, Kopuz A et al. Diagnosis of primary langerhans cell histiocytosis of the vulva in a postmenopausal woman. Case Rep Obstet Gynecol 2013; 2013: 962670.
8. Madnani NA, Khan KJ. Vulvar ulcer as a presentation of systemic langerhans cell histiocytosis. Indian J Dermatol Venereol Leprol 2011; 77: 177–9.
9. Simons M, Van De Nieuwenhof HP, Van Der Avoort IA et al. A patient with lichen sclerosus, Langerhans cell histiocytosis, and invasive squamous cell carcinoma of the vulva. Am J Obstet Gynecol 2010; 203 (2): e7–10.
10. Triantafyllidou O, Giannakopoulos K, Pergialiotis V et al. Pure vulvar Langerhans cell histiocytosis: a case report and literature review. Eur J Gynaecol Oncol 2009; 30 (6): 691–4.
11. El Fekih N, Kamoun I, Jones M et al. Histiocytosis X revealed by diabetes insipidus and skin lesions. Am J Dermatopathol 2013; 35 (5): 606–8.
12. Khoummane N, Guimeya C, Lipombi D, Gielen F. Vulvar Langerhans cell histiocytosis: a case report. Pan African Medical J 2014; 18: 119.
13. Lajolo C, Campisi G, Deli G et al. Langerhans’s cell histiocytosis in old subjects: two rare case reports and review of the literature. Gerodontology 2012; 29 (2): e1207–14.
14. Grois N, Pötschger U, Prosch H et al. DALHX- and LCH I and II Study Committee. Risk factors for diabetes insipidus in langerhans cell histiocytosis. Pediatr Blood Cancer 2006; 46 (2): 228–33.
15. Pedrosa AF, Lisboa C, Ferreira O et al. Primary Langerhans cell histiocytosis of the vulva: acitretin as a glucocorticoid-sparing agent. Int J Dermatol 2014; 53 (4): e294–6.
2. Morimoto A, Oh Y, Shioda Y et al. Recent advances in Langerhans Cell Histiocytosis. Pediatr Int 2014 May 19.
3. El-Safadi S, Dreyer T, Oehmke F, Muenstedt K. Management of adult primary vulvar Langerhans cell histiocytosis: review of the literature and a case history. Eur J Obstet Gynecol Reprod Biol 2012; 163 (2): 123–8.
4. Chang JC, Blake DG, Leung BV, Plaza JA. Langerhans cell histiocytosis associated with lichen sclerosus of the vulva: case report and review of the literature. J Cutan Pathol 2013; 40 (2): 279–83.
5. Foley S, Panting K, Bell H et al. Rapid resolution of primary vulval adult Langerhans cell histiocytosis with very potent topical corticosteroids. Australas J Dermatol 2011; 52 (1): e8–e14.
6. Jiang W(I), Li L, He YM, Yang KX. Langerhans cell histiocytosis of the female genital tract: a literature review with additional three case studies in China. Arch Gynecol Obstet 2012; 285 (1): 99–103.
7. Kurt S, Canda MT, Kopuz A et al. Diagnosis of primary langerhans cell histiocytosis of the vulva in a postmenopausal woman. Case Rep Obstet Gynecol 2013; 2013: 962670.
8. Madnani NA, Khan KJ. Vulvar ulcer as a presentation of systemic langerhans cell histiocytosis. Indian J Dermatol Venereol Leprol 2011; 77: 177–9.
9. Simons M, Van De Nieuwenhof HP, Van Der Avoort IA et al. A patient with lichen sclerosus, Langerhans cell histiocytosis, and invasive squamous cell carcinoma of the vulva. Am J Obstet Gynecol 2010; 203 (2): e7–10.
10. Triantafyllidou O, Giannakopoulos K, Pergialiotis V et al. Pure vulvar Langerhans cell histiocytosis: a case report and literature review. Eur J Gynaecol Oncol 2009; 30 (6): 691–4.
11. El Fekih N, Kamoun I, Jones M et al. Histiocytosis X revealed by diabetes insipidus and skin lesions. Am J Dermatopathol 2013; 35 (5): 606–8.
12. Khoummane N, Guimeya C, Lipombi D, Gielen F. Vulvar Langerhans cell histiocytosis: a case report. Pan African Medical J 2014; 18: 119.
13. Lajolo C, Campisi G, Deli G et al. Langerhans’s cell histiocytosis in old subjects: two rare case reports and review of the literature. Gerodontology 2012; 29 (2): e1207–14.
14. Grois N, Pötschger U, Prosch H et al. DALHX- and LCH I and II Study Committee. Risk factors for diabetes insipidus in langerhans cell histiocytosis. Pediatr Blood Cancer 2006; 46 (2): 228–33.
15. Pedrosa AF, Lisboa C, Ferreira O et al. Primary Langerhans cell histiocytosis of the vulva: acitretin as a glucocorticoid-sparing agent. Int J Dermatol 2014; 53 (4): e294–6.
Авторы
И.В.Поддубная, Е.л.Разумова, Ю.Е.кижаев, Е.А.Уколова, к.А.Тетерин
ГБОУ ДПО Российская медицинская академия последипломного образования Минздрава России, Москва
ГБОУ ДПО Российская медицинская академия последипломного образования Минздрава России, Москва
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