Солитарный метастаз колоректального рака в левом надпочечнике через 4 года после операции на первичной опухоли. Клинический случай

Будурова М.Д., Трифанов В.С., Копылов В.В., Кузнецова О.С., Черниченко М.А., Полуэктов С.И. Солитарный метастаз колоректального рака в левом надпочечнике через 4 года после операции на первичной опухоли. Клинический случай. Современная Онкология. 2023;25(3):401–405. DOI: 10.26442/18151434.2023.3.202355

© ООО «КОНСИЛИУМ МЕДИКУМ», 2023 г.

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Budurova MD, Trifanov VS, Kopylov VV, Kuznetsova OS, Chernichenko MA, Poluektov SI. Solitary metastasis of colorectal cancer in the left adrenal gland 4 years after surgery on the primary tumor. Case report. Journal of Modern Oncology. 2023;25(3):401–405. DOI: 10.26442/18151434.2023.3.202355

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Аннотация

Колоректальный рак (КРР) является одним из самых распространенных онкологических заболеваний. В среднем в 20–25% случаев после радикального хирургического лечения КРР у пациентов отмечается прогрессирование заболевания в виде метахронных метастазов в печени и легких как наиболее часто встречающихся локализаций метастазов КРР. С появлением новых стратегий лекарственного лечения КРР наблюдается увеличение общей выживаемости, в результате чего метастазы КРР в надпочечниках стали встречаться чаще, чем считалось ранее, и количество опубликованных сообщений о случаях метастазирования КРР в надпочечники увеличилось. В данной статье мы сообщаем о редком клиническом наблюдении метахронного солитарного метастазирования КРР в левый надпочечник через 4 года после радикального хирургического лечения первичной опухоли: больному выполнена радикальная левосторонняя адреналэктомия. Срок наблюдения пациента без признаков прогрессирования и рецидива заболевания – 6 мес (на момент публикации).

Ключевые слова: колоректальный рак, отдаленные метастазы колоректального рака, солитарный метастаз колоректального рака, метахронные метастазы колоректального рака, метастаз колоректального рака в надпочечник

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Colorectal cancer (CRC) is one of the most common oncological diseases. On average, in 20–25% of cases after radical surgical treatment of CRC, the progression of the disease in the form of metachronous metastases in the liver and lungs, as the most common localization of CRC metastases, is noted in patients. With the advent of new drug treatment strategies for CRC, there is an increase in overall survival, as a result of which CRC metastases in the adrenal glands have become more common than previously thought, and the number of published reports of cases of CRC metastasis in the adrenal glands has increased. In this article, we report a rare clinical observation of metachronous solitary metastasis of CRC to the left adrenal gland 4 years after radical surgical treatment of the primary tumor: the patient underwent radical left-sided adrenalectomy. The period of observation of the patient without signs of progression and relapse of the disease is 6 months (at the time of publication).

Keywords: colorectal cancer, distant metastases of colorectal cancer, solitary metastasis of colorectal cancer, metachronous metastases of colorectal cancer, metastasis of colorectal cancer to the adrenal gland

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Список литературы

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21. Liu YY, Chen ZH, Zhai ET, et al. Case of metachronous bilateral isolated adrenal metastasis from colorectal adenocarcinoma and review of the literature. World J Gastroenterol. 2016;22(14):3879-84. DOI:10.3748/wjg.v22.i14.3879
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24. Moreno-Elola A, Moreno-Gonzalez E, Alonso-Casado O, et al. Exceptional bilateral adrenalectomy after secondaries from colorectal cancer. Hepatogastroenterology.
2004;51(55):103-5. PMID:15011840
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27. Yamada T, et al. A resected case of adrenal metastasis from colon cancer (in Japanese). Shujutsu (Operation). 2001;55:1421-5.
28. Alvandipour M, Karami MY, Khalvati M, Khodabakhsh H. Incidentally solitary, synchronous, metastatic left adrenal mass from colon cancer. Ann Coloproctol. 2016;32(2):79-82. DOI:10.3393/ac.2016.32.2.79
29. Sancho JJ, Triponez F, Montet X, Sitges-Serra A. Surgical management of adrenal metastases. Langenbecks Arch Surg. 2012;397(2):179-94. DOI:10.1007/s00423-011-0889-1
30. Capaldi M, Ricci G, Bertolini R, et al. Colon cancer adrenal metastasis: Case report and review of the literature. G Chir. 2011;32(8-9):361-3. PMID:22018256
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________________________________________________

1. Shimomura M, Okajima M, Hinoi T, et al. Identification of patients likely to benefit from metastasectomy in stage IV colorectal cancer. Int J Colorectal Dis. 2012;27(10):1339-46. DOI:10.1007/s00384-012-1454-2
2. Mahmoud N, Bullard Dunn K. Metastasectomy for stage IV colorectal cancer. Dis Colon Rectum. 2010;53(7):1080-92. DOI:10.1007/DCR.0b013e3181dcadbc
3. Tsujimoto A, Ueda T, Kuge H, et al. Long-term survival after adrenal metastasectomy from colorectal cancer: a report of two cases. Surg Case Rep. 2019;5(1):61.
DOI:10.1186/s40792-019-0611-z
4. Vishnevskii AV, Andreytseva OI, Kharazov AF, et al. Epinephros metastasis of colorectal cancer complicated by tumor thrombosis of inferior vena cava. Pirogov Russian Journal of Surgery = Khirurgiya. Zurnal im. N.I. Pirogova. 2015;(1):68-72 (in Russian). DOI:10.17116/hirurgia2015168-72
5. Moreno P, de la Quintana Basarrate A, Musholt TJ, et al. Adrenalectomy for solid tumor metastases: Results of a multicenter European study. Surgery. 2013;154(6):1215-22;
discussion 1222-3. DOI:10.1016/j.surg.2013.06.021
6. Shoji Y, Dohke M, Masuda T, et al. Solitary adrenal metastasis in a patient with sigmoid colon cancer; report of a case. Int J Gastrointest Cancer. 2006;37(4):120‑3. DOI:10.1007/s12029-007-9001-z
7. Muth A, Persson F, Jansson S, et al. Prognostic factors for survival after surgery for adrenal metastasis. Eur J Surg Oncol. 2010;36(7):699-704. DOI:10.1016/j.ejso.2010.04.002
8. Thrumurthy SG, Jadav AM, Pitt M, et al. Metachronous bilateral adrenal metastases following curative treatment for colorectal carcinoma. Ann R Coll Surg Engl. 2011;93(6):e96-8. DOI:10.1308/147870811X591134
9. Uemura M, Kim HM, Ikeda M, et al. Long-term outcome of adrenalectomy for metastasis resulting from colorectal cancer with other metastatic sites: A report of 3 cases. Oncol Lett. 2016;12(3):1649-54. DOI:10.3892/ol.2016.4897
10. Jabir H, Tawfiq N, Moukhlissi M, et al. Metachronous bilateral isolated adrenal metastasis from rectal adenocarcinoma: A case report. Case Rep Gastrointest Med. 2014;2014:516403. DOI:10.1155/2014/516403
11. Muñoz-Atienza V, Manzanares-Campillo MC, Sánchez-García S, et al. Bilateral laparoscopic adrenalectomy for synchronous metastasis of colonic cancer. Int J Colorectal Dis. 2012;27(10):1389-90. DOI:10.1007/s00384-012-1429-3
12. Kosmidis C, Efthimiadis C, Anthimidis G, et al. Adrenalectomy for solitary adrenal metastasis from colorectal cancer: a case report. Cases J. 2008;1(1):49.
DOI:10.1186/1757-1626-1-49
13. Murakami S, Terakado M, Hashimoto T, et al. Adrenal metastasis from rectal cancer: Report of a case. Surg Today. 2003;33(2):126-30. DOI:10.1007/s005950300028
14. Moshurov IP, Sidorov DV, Golovkov DA, et al. Clinical case of a massive isolated metastatic adrenal lesion in colorectal cancer. Issled. Prakt. Med. 2015; 2(3):89‑92 (in Russian). DOI:10.17709/2409-2231-2015-2-3-89-92
15. Katayama A, Mafune K, Makuuchi M. Adrenalectomy for solitary adrenal metastasis from colorectal carcinoma. Jpn J Clin Oncol. 2000;30(9):414-6. DOI:10.1093/jjco/hyd104
16. Chen L, Wang D, Mao W, et al. A case of long-term survival after curative resection for synchronous solitary adrenal metastasis from rectal cancer. Pak J Med Sci. 2014;30(1):216-9. DOI:10.12669/pjms.301.4341
17. Mourra N, Hoeffel C, Duvillard P, et al. Adrenalectomy for clinically isolated metastasis from colorectal carcinoma: report of eight cases. Dis Colon Rectum. 2008;51(12):1846-9. DOI:10.1007/S10350-008-9235-2
18. de Haas RJ, Rahy Martin AC, Wicherts DA, et al. Long-term outcome in patients with adrenal metastases following resection of colorectal liver metastases. Br J Surg.
2009;96(8):935-40. DOI:10.1002/bjs.6646
19. Kanjo T, Albertini M, Weber S. Long-term disease-free survival after adrenalectomy for isolated colorectal metastases. Asian J Surg. 2006;29(4):291‑3.
DOI:10.1016/S1015-9584(09)60105-6
20. Raices M, Boccalatte L, Rossi G, Wright F. Synchronous contralateral adrenal metastasis of colorectal cancer: case report. J Surg Case Rep. 2017;2017(6):rjx098. DOI:10.1093/jscr/rjx098
21. Liu YY, Chen ZH, Zhai ET, et al. Case of metachronous bilateral isolated adrenal metastasis from colorectal adenocarcinoma and review of the literature. World J Gastroenterol. 2016;22(14):3879-84. DOI:10.3748/wjg.v22.i14.3879
22. Tsuchida K, Watanabe H, Kameda Y, et al. A case of solitary adrenal metastasis from rectal cancer treated by adrenalectomy after preoperative chemotherap. Gan To Kagaku Ryoho. 2016;43(12):1751-3. PMID:28133120 Japanese
23. Chen L, Wang D, Mao W, et al. A case of longterm survival after curative resection for synchronous solitary adrenal metastasis from rectal cancer. Pak J Med Sci. 2014;30(1):216-9. DOI:10.12669/pjms.301.4341
24. Moreno-Elola A, Moreno-Gonzalez E, Alonso-Casado O, et al. Exceptional bilateral adrenalectomy after secondaries from colorectal cancer. Hepatogastroenterology.
2004;51(55):103-5. PMID:15011840
25. Falcone A, Ricci S, Brunetti I, et al. Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: The Gruppo Oncologico Nord Ovest. J Clin Oncol. 2007;25(13):1670-6. DOI:10.1200/JCO.2006.09.0928
26. Masuyama K, Shimada K, Uotani H, et al. A case of rectal cancer with metastasis to left adrenal cortical carcinoma (in Japanese with English abstract). Geka Gakkai Zasshi (J Jpn Surg Assoc). 2001;62:192-6.
27. Yamada T, et al. A resected case of adrenal metastasis from colon cancer (in Japanese). Shujutsu (Operation). 2001;55:1421-5.
28. Alvandipour M, Karami MY, Khalvati M, Khodabakhsh H. Incidentally solitary, synchronous, metastatic left adrenal mass from colon cancer. Ann Coloproctol. 2016;32(2):79-82. DOI:10.3393/ac.2016.32.2.79
29. Sancho JJ, Triponez F, Montet X, Sitges-Serra A. Surgical management of adrenal metastases. Langenbecks Arch Surg. 2012;397(2):179-94. DOI:10.1007/s00423-011-0889-1
30. Capaldi M, Ricci G, Bertolini R, et al. Colon cancer adrenal metastasis: Case report and review of the literature. G Chir. 2011;32(8-9):361-3. PMID:22018256
31. Crisci A, Cartei G, De Antoni P, et al. Surgical management of isolated bilateral adrenal metastases from colon carcinoma causing adrenal insufficiency. Urol Int. 2001;67(1):113-6. DOI:10.1159/000050963
32. Hayashi H, Murase Y, Sano H, et al. Complete resection of rectal cancer with a synchronous solitary adrenal metastasis: A case report. Int J Surg Case Rep. 2020;75:242-5. DOI:10.1016/j.ijscr.2020.09.094

Авторы

М.Д. Будурова*^1,2, В.С. Трифанов^1,3, В.В. Копылов¹, О.С. Кузнецова¹, М.А. Черниченко¹, С.И. Полуэктов¹

¹Московский научно-исследовательский онкологический институт им. П.А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России, Москва, Россия;
²ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Минздрава России, Москва, Россия;
³ФГАОУ ВО «Российский университет дружбы народов», Москва, Россия
*m.budurova@rambler.ru

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Marina D. Budurova*^1,2, Vladimir S. Trifanov^1,3, Vladimir V. Kopylov¹, Olga S. Kuznetsova¹, Maria A. Chernichenko¹, Sergey I. Poluektov¹

¹Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Moscow, Russia;
²Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia;
³Peoples' Friendship University of Russia (RUDN University), Moscow, Russia
*m.budurova@rambler.ru

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