1. Желудкова О.Г., Шишкина А.В., Коновалов А.Н., и др. Синдром растущей тератомы у пациента с интракраниальной герминативно-клеточной опухолью. Журнал «Вопросы нейрохирургии» им. Н.Н. Бурденко. 2015;79(3):69-74 [Zheludkova OG, Shishkina LV, Konovalov AN, et al. Growing teratoma syndrome in patient with intracranial germ cell tumor. Burdenko’s Journal of Neurosurgery. 2015;79(3):69-74 (in Russian)]. DOI:10.17116/neiro201579369-74
2. Синиченкова К.Ю., Тютикова У.С., Ликарь Ю.Н., и др. Сложности диагностики синдома растущей тератомы на примере двух клинических наблюдений. Вопросы гематологии/онкологии и иммунологии в педиатрии. 2020;19(4):126-52 [Sinichenkova KYu, Tyutikova ES, Likar YuN, et al. Challenges in the diagnosis of growing teratoma syndrome: two case reports. Pediatric Hematology/Oncology and Immunopathology. 2020;19(4):126-52 (in Russian)]. DOI:10.2428/1726-1708-2020-19-4-126-132
3. Калимуллин Б.А., Осипова И.В., Шапиро В.Ю., и др. Клинический случай синдрома растущей тератомы у подростка с герминогенной опухолью яичка. Вопросы гематологии/онкологии и иммунологии в педиатрии. 2023;22(4):144-50 [Kalimullin BA, Osipova IV, Shapiro VYu, et al. Growing teratoma syndrome in an adolescent with a testicular germ cell tumor: a case report. Pediatric Hematology/Oncology and Immunopathology. 2023;22(4):144-50 (in Russian)]. DOI:10.24287/1726-1708-2023-22-4-144-150
4. Logothetis CJ, Samuels MI, Trindade A, Johnson DE. The growing teratome syndrome. Cancer. 1982;50(8):1629-35. 
5. Jeffery GM, Theaker JM, Lee AH, et al. The growing teratoma syndrome. Br J Urol. 1991;67(2):195-202.
6. Tangjtgamol S, Manusirivithaya S, Leelahakom S, et al. The growing teratoma syndrome: a case report and a review of literature. Int J Gynecol Cancer. 2006;16):384-90. 
7. Soufi M, Lupinacci RM, Godiris-Petit G, et al. Growing teratoma syndrome of the ovary presenting with liver metastasis: report of a case. Eur J Gynecol Oncol. 2015;36(4):473-6. 
8. Moscovic E, Jobling T, Fisher C, et al. Retroconversion of immature teratoma of the ovary: CT appearances. Clin Radiol. 1991;43(6):402-8.
9. Andre F, Fizazi K, Culine S, et al. The growing teratoma syndrome: results of therapy and long-term follow-up of 33 patients. Eur J Cancer. 2000;36(11):1389-94. 
10. Tongaonkar HB, Deshmane VH, Dalal AV, et al. Growing teratoma syndrome. J Surg Oncol. 1994;55(1):56-60. 
11. Nimkin K, Gupta P, McCauley R, et al. The growing teratoma syndrome. Pediatr Radiol. 2004;34(3):259-62.
12. Outwater EK, Siegelman ES, Hunt JL. Ovarian teratomas: tumor types and imaging characteristics. Radiographics . 2001;21:475-90.
13. Lee DJ, Djaladat H, Tadros NN, et al. Growing teratoma syndrome: clinical and radiographic characteristics. Int J Urol. 2014;21:905-8. DOI:10.1111/iju.12466
14. Aide N, Comoz F, Sevin E. Enlarging residual mass after treatment of a nonseminomatous germ cell tumor: growing teratoma syndrome or cancer recurrence? J Clin Oncol. 2007;25:4494-6. DOI:10.1200/JCO.2007.12.7530
15. Hariprasad R, Kumar L, Janga D, et al. Growing teratoma syndrome of ovary. Int J Clin Oncol. 2008;13:83-7. 
16. Kikawa S, Todo Y, Minobe S, et al. Growing teratoma syndrome of the ovary: a case report with FDG-PET findings. J Obstet Gynaecol Res. 2011;37(7):926-32.
17. Best DH, Butz GM, Moller K, et al. Molecular analysis of an immature ovarian teratoma with gliomatosis peritonei and recurrence suggest genetic independence of multiple tumors. Int J Oncol. 2004;25(1):17-25. 
18. Kwan MY, Kalle W, Lau GT, Chan JK. Is gliomatosis peritonei derived from the associated ovarian teratoma. Hum Pathol. 2004;35:685-8.
19. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126:663-76.
20. Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007;131:861-72.
21. Nogales EF, Preda O, Dulcey I. Gliomatosis peritonei as a natural experiment in tissue differentiation. Int J Dev Biol. 2012;56:969-74. 
22. Maucksch C, Jones KS, Connor B. Concise review: the involvement of Sox2 in direct reprogramming of induced neural stem/precursor cell. Stem Cells Transl Med. 2013;2:579-83.
23. Liang L, Zhang Y, Malpica A, et al. Gliomatosis peritonei: a clinicopathologic and immunohistochemical study of 21 cases. Mod Pathol. 2015;28:1613-20.
24. Zhao T, Liu Y, Jiang H, et al. Management of bilateral malignant ovarian germ cell tumors: Experience of a single institute. Mol Clin Oncol. 2016;5(2):383-7.
25. Phi JH, Park SH, Paek SH, et al. Expression of SOX2 in mature and immature teratomas of central nervous system. Mod Pathol. 2007;20:742-8. DOI;10.1038/modpathol.3800793
26. Truong LD, Jurco S, McGavran MH. Gliomatosis Peritonei: report of two cases and review of the literature. Am J Surg Pathol. 1982;6:443-9. 
27. Gu S, Wu YM, Hong L, et al. Glial fibrillary acidic protein expression is an indicator of teratoma maturation in children. World J Pediatr. 2011;7:262-5. 
28. Wang D, Jia CW, Feng RE, et al. Gliomatosis peritonei: a series of eight cases and review of the literature. J Ovarian Res. 2016;9(1):45-51. DOI:10.1186/s13048-016-0256-5
29. Tullius BP, Shankar SP, Cole S, et al. Novel heterozygous mutation in the PTEN gene associated with ovarian germ cell tumor complicated by growing teratoma syndrome and overgrowing in two-year-old female. Pediatr Blood Cancer. 2019:e27788. DOI:10.1002/pbc.27788
30. Willis GW, Hajdu SI. Histologically benign teratoid metastasis of testicular embryonal carcinoma: report of five cases. Am J Clin Pathol. 1973;59(3):338-43.
31. Spiess PE, Kassouf W, Brown GA, et al. Surgical management of growing teratoma syndrome: the M.D. Anderson cancer center experience. J Urol. 2007;177(4):1330-4. 
32. Gorbatiy V, Spiess PE, Pisters LL. The growing teratoma syndrome: current review of the literature. Indian J Urol. 2009;25:186-9.
33. Scavuzzo A, Santana Rios ZA, Noveron NR, Jimenez Rios MA. Growing teratoma syndrome. Case Rep Urol. 2014;2014:139425. DOI:10.1155/2014/139425
34. Matsushita H, Arai K, Fukase M, et al. Growing teratoma syndrome of the ovary after fertility-sparing surgery and successful pregnancy. Gynecol Obstet Invest. 2010;69(4):221-3. DOI:10.1159/000273205

________________________________________________

1. Zheludkova OG, Shishkina LV, Konovalov AN, et al. Growing teratoma syndrome in patient with intracranial germ cell tumor. Burdenko’s Journal of Neurosurgery. 2015;79(3):69-74 (in Russian). DOI:10.17116/neiro201579369-74
2. Sinichenkova KYu, Tyutikova ES, Likar YuN, et al. Challenges in the diagnosis of growing teratoma syndrome: two case reports. Pediatric Hematology/Oncology and Immunopathology. 2020;19(4):126-52 (in Russian). DOI:10.2428/1726-1708-2020-19-4-126-132
3. Kalimullin BA, Osipova IV, Shapiro VYu, et al. Growing teratoma syndrome in an adolescent with a testicular germ cell tumor: a case report. Pediatric Hematology/Oncology and Immunopathology. 2023;22(4):144-50 (in Russian). DOI:10.24287/1726-1708-2023-22-4-144-150
4. Logothetis CJ, Samuels MI, Trindade A, Johnson DE. The growing teratome syndrome. Cancer. 1982;50(8):1629-35. 
5. Jeffery GM, Theaker JM, Lee AH, et al. The growing teratoma syndrome. Br J Urol. 1991;67(2):195-202.
6. Tangjtgamol S, Manusirivithaya S, Leelahakom S, et al. The growing teratoma syndrome: a case report and a review of literature. Int J Gynecol Cancer. 2006;16):384-90. 
7. Soufi M, Lupinacci RM, Godiris-Petit G, et al. Growing teratoma syndrome of the ovary presenting with liver metastasis: report of a case. Eur J Gynecol Oncol. 2015;36(4):473-6. 
8. Moscovic E, Jobling T, Fisher C, et al. Retroconversion of immature teratoma of the ovary: CT appearances. Clin Radiol. 1991;43(6):402-8.
9. Andre F, Fizazi K, Culine S, et al. The growing teratoma syndrome: results of therapy and long-term follow-up of 33 patients. Eur J Cancer. 2000;36(11):1389-94. 
10. Tongaonkar HB, Deshmane VH, Dalal AV, et al. Growing teratoma syndrome. J Surg Oncol. 1994;55(1):56-60. 
11. Nimkin K, Gupta P, McCauley R, et al. The growing teratoma syndrome. Pediatr Radiol. 2004;34(3):259-62.
12. Outwater EK, Siegelman ES, Hunt JL. Ovarian teratomas: tumor types and imaging characteristics. Radiographics . 2001;21:475-90.
13. Lee DJ, Djaladat H, Tadros NN, et al. Growing teratoma syndrome: clinical and radiographic characteristics. Int J Urol. 2014;21:905-8. DOI:10.1111/iju.12466
14. Aide N, Comoz F, Sevin E. Enlarging residual mass after treatment of a nonseminomatous germ cell tumor: growing teratoma syndrome or cancer recurrence? J Clin Oncol. 2007;25:4494-6. DOI:10.1200/JCO.2007.12.7530
15. Hariprasad R, Kumar L, Janga D, et al. Growing teratoma syndrome of ovary. Int J Clin Oncol. 2008;13:83-7. 
16. Kikawa S, Todo Y, Minobe S, et al. Growing teratoma syndrome of the ovary: a case report with FDG-PET findings. J Obstet Gynaecol Res. 2011;37(7):926-32.
17. Best DH, Butz GM, Moller K, et al. Molecular analysis of an immature ovarian teratoma with gliomatosis peritonei and recurrence suggest genetic independence of multiple tumors. Int J Oncol. 2004;25(1):17-25. 
18. Kwan MY, Kalle W, Lau GT, Chan JK. Is gliomatosis peritonei derived from the associated ovarian teratoma. Hum Pathol. 2004;35:685-8.
19. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126:663-76.
20. Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007;131:861-72.
21. Nogales EF, Preda O, Dulcey I. Gliomatosis peritonei as a natural experiment in tissue differentiation. Int J Dev Biol. 2012;56:969-74. 
22. Maucksch C, Jones KS, Connor B. Concise review: the involvement of Sox2 in direct reprogramming of induced neural stem/precursor cell. Stem Cells Transl Med. 2013;2:579-83.
23. Liang L, Zhang Y, Malpica A, et al. Gliomatosis peritonei: a clinicopathologic and immunohistochemical study of 21 cases. Mod Pathol. 2015;28:1613-20.
24. Zhao T, Liu Y, Jiang H, et al. Management of bilateral malignant ovarian germ cell tumors: Experience of a single institute. Mol Clin Oncol. 2016;5(2):383-7.
25. Phi JH, Park SH, Paek SH, et al. Expression of SOX2 in mature and immature teratomas of central nervous system. Mod Pathol. 2007;20:742-8. DOI;10.1038/modpathol.3800793
26. Truong LD, Jurco S, McGavran MH. Gliomatosis Peritonei: report of two cases and review of the literature. Am J Surg Pathol. 1982;6:443-9. 
27. Gu S, Wu YM, Hong L, et al. Glial fibrillary acidic protein expression is an indicator of teratoma maturation in children. World J Pediatr. 2011;7:262-5. 
28. Wang D, Jia CW, Feng RE, et al. Gliomatosis peritonei: a series of eight cases and review of the literature. J Ovarian Res. 2016;9(1):45-51. DOI:10.1186/s13048-016-0256-5
29. Tullius BP, Shankar SP, Cole S, et al. Novel heterozygous mutation in the PTEN gene associated with ovarian germ cell tumor complicated by growing teratoma syndrome and overgrowing in two-year-old female. Pediatr Blood Cancer. 2019:e27788. DOI:10.1002/pbc.27788
30. Willis GW, Hajdu SI. Histologically benign teratoid metastasis of testicular embryonal carcinoma: report of five cases. Am J Clin Pathol. 1973;59(3):338-43.
31. Spiess PE, Kassouf W, Brown GA, et al. Surgical management of growing teratoma syndrome: the M.D. Anderson cancer center experience. J Urol. 2007;177(4):1330-4. 
32. Gorbatiy V, Spiess PE, Pisters LL. The growing teratoma syndrome: current review of the literature. Indian J Urol. 2009;25:186-9.
33. Scavuzzo A, Santana Rios ZA, Noveron NR, Jimenez Rios MA. Growing teratoma syndrome. Case Rep Urol. 2014;2014:139425. DOI:10.1155/2014/139425
34. Matsushita H, Arai K, Fukase M, et al. Growing teratoma syndrome of the ovary after fertility-sparing surgery and successful pregnancy. Gynecol Obstet Invest. 2010;69(4):221-3. DOI:10.1159/000273205

И.В. Нечушкина*¹, Н.А. Сусулева^1,2, Е.И. Бойченко^1,2, В.М. Нечушкина^3,4, П.А. Керимов², А.Б. Рябов<sup>5

1</sup>ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Москва, Россия;
²ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России, Москва, Россия;
³АНО «Научно-образовательный центр “Евразийская онкологическая программа “ЕАФО”», Москва, Россия;
⁴ФГБОУ ВО «Приволжский исследовательский медицинский университет» Минздрава России, Нижний Новгород, Россия;
⁵ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России, Москва, Россия
*ivnechushkina@mail.ru

________________________________________________

Innesa V. Nechushkina*¹, Natalja A. Susuleva^1,2, Elena I. Boychenko^1,2, Valentina M. Nechushkina^3,4, Polad A. Kerimov², Andrey B. Ryabov<sup>5

1</sup>Russian Medical Academy of Continuous Professional Education, Moscow, Russia;
²Blokhin National Medical Research Center of Oncology, Moscow, Russia;
³Educational and Research Center “Eurasian Oncology Program “EAFO” ANO, Moscow, Russia;
⁴Privolzhsky Research Medical University, Nizhny Novgorod, Russia;
⁵National Medical Research Radiological Centre, Moscow, Russia
*ivnechushkina@mail.ru