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Злокачественная гигантоклеточная опухоль мягких тканей (клиническое наблюдение)
Злокачественная гигантоклеточная опухоль мягких тканей (клиническое наблюдение)
Ващенко Л.Н., Тодоров С.С., Аушева Т.В. и др. Злокачественная гигантоклеточная опухоль мягких тканей (клиническое наблюдение). Современная онкология. 2015; 17 (2): 57–60.
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Аннотация
Клиническое наблюдение показывает упорно рецидивирующее течение, которым характеризуются злокачественные гигантоклеточные опухоли мягких тканей, даже при низком потенциале злокачественности и при отсутствии отдаленного метастазирования.
Ключевые слова: злокачественные гигантоклеточные опухоли мягких тканей, рецидивы.
Key words: malignant giant cell tumor of soft tissues, relapse.
Ключевые слова: злокачественные гигантоклеточные опухоли мягких тканей, рецидивы.
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Key words: malignant giant cell tumor of soft tissues, relapse.
Полный текст
Список литературы
1. Алиев М.Д., Бохян Б.Ю. Опухоли мягких тканей. Энциклопедия клинической онкологии. М., 2004; 365–66. / Aliev M.D., Bokhian B.Iu. Opukholi miagkikh tkanei. Entsiklopediia klinicheskoi onkologii. M., 2004; 365–66. [in Russian]
2. Васильев Н.В., Мухамедов М.Р., Чойнзонов Е.Л. и др. Жамгарян Гигантоклеточные опухоли: обзор литературы. Сиб. онкологический журн. 2011; 5 (47): 64–9. / Vasil'ev N.V., Mukhamedov M.R., Choinzonov E.L. i dr. Zhamgarian Gigantokletochnye opukholi: obzor literatury. Sib. onkologicheskii zhurn. 2011; 5 (47): 64–9. [in Russian]
3. Коноваленко В.А. Клиника, дифференциальная диагностика и стадирование сарком мягких тканей. Практическая онкология. 2005; 5 (4): 32. / Konovalenko V.A. Klinika, differentsial'naia diagnostika i stadirovanie sarkom miagkikh tkanei. Prakticheskaia onkologiia. 2005; 5 (4): 32. [in Russian]
4. Чиссов В.И, Трахтенберг А.Х. Ошибки в клинической онкологии. Изд. 3-е. М., 2009; 754–68. / Chissov V.I, Trakhtenberg A.Kh. Oshibki v klinicheskoi onkologii. Izd. 3-e. M., 2009; 754–68. [in Russian]
5. Аsuquo ME, Nwagbara VI, Agbor C et al. Giant Cell Tumour of Soft Tissue of the Finger: A Case Report. J Clin Exp Oncol 2013; 2: 3.
6. Аngervall L, Hagmar B, Kindblom LG, Merck C. Malignant giant cell tumor of soft tissues: a clinicopathologic, cytologic, ultrastructural, angiographic, and microangiographic study. Cancer 1981; 47: 736–47.
7. Bertoni F, Bacchini P, Staals E. Malignancy in giant cell tumor of bone. Cancer 2003; 97: 2520–9.
8. Brien EW, Mirra JM, Kessler S et al. Benign giant cell tumor of bone with osteosarcomatous transformation (“dedifferentiated” primary malignant GCT): report of two cases. Skeletal Radiol 1997.
9. Chan Y-J, Chao T-K, Chu Y-H, Wang H-W. Giant cell tumor of soft tissue of neck. J Med Sci 2009; 29 (6): 353–5.
10. Dahlin DC, Cupps RE, Johnson EW. Giant cell tumor: a study of 195 cases. Cancer 1970; 25: 1061–70.
11. Shah DR, Gaw F, Balderrama DC et al. Brown Malignant Giant Cell Tumor of the Soft Tissues of the Neck: Case report Hospital Physician January, 2001; p. 52–5.
12. Fletcher CDM, Unni KK, Mertens F eds. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon, France: IARC Press; World Health Organization Classification of Tumours 2002; 5.
13. Folpe AL, Morris RJ, Weiss SW. Soft tissue giant cell tumor of low malignant potential: a proposal for the reclassification of malignant giant cell tumor of soft parts. Mod Pathol 1999; 12: 894–902.
14. Gitelis S, Wang JW, Quast M et al. Recurrence of a giantcell tumor with malignant transformation to a fibrosarcoma twenty-five years after primary treatment. A case report. J Bone Joint Surg Am.
15. Guccion JG, Enzinger FM. Malignant giant cell tumor of soft parts. An analysis of 32 cases. Cancer 1972; 29: 1518–29.
16. Hashimoto K, Hatori M, Hosaka M et al. Osteosarcoma arising from giant cell tumor of bone ten years after primary surgery: a case report and review of the literature. Tohoku J Exp Med 2006; 208: 157–62.
17. Hong S-W, Choi H-Y. Malignant giant cell tumor of the skull. J Korean Neurosurg Soc 2004; 36: 324–7.
18. Hutter RVP, Worcester JN, Francis KC et al. Benign and malignant giant cell tumor of bone. A clinicopathological analysis of the natural history of the disease. Cancer 1962; 15: 653–90.
19. Junior RZB, Camargo OP, Ida CM et al. Primary malignancy in giant cell tumor: a case report. Sao Paulo Med J 2009; 127 (5): 310–3.
20. Junior RZB, Camargo OP, Ida CM et al. Primary malignancy in giant cell tumor: a case report. San Paulo Med J 2009; 127 (5): 310–3.
21. Kumar S, Carter LF. Giant cell tumor of soft tissue of hand: simple but rare diagnosis, which is often missed. Clin Pract 2011; 1: e54.
22. Machinami R, Nishida K, Ishida T et al. Carcinosarcomatousmalignancy, osteosarcoma and squamous cell carcinoma, in giant cell tumor of the right distal femur. Pathol Res Pract 2008; 204.
23. McGrath PJ. Giant-cell tumor of bone: an analysis of fifty two cases. J Bone Joint Surg Br 1972; 54: 216–29.
24. Murphey MD, Nomikos GC, Flemming DJ et al. Imaging of Giant Cell Tumor and Giant Cell Reparative Granuloma of Bone: Radiologic-Pathologic Correlation. Radio Graphics 2001; 21.
25. Nguyen V, Garcia C, Haskell H. Giant cell tumor of soft tissue on the thigh of a 40-year-old woman. Dermatol Online J 2010. 16: 2.
26. Oda Y, Sakamoto A, Saito T et al. Secondary malignant giant-cell tumor of bone: molecular abnormalities of p53 and H-ras gene correlated with malignant transformation. Histopathology 2001; p. 1283–309.
27. Rock MG, Sim FH, Unni KK et al. Secondary malignant giant-cell tumor of bone. Clinicopathological assessment of nineteen patients. J Bone Joint Surg Am 1986; 68: 1073–9.
28. Salm R, Sissons H.A. Giant-cell tumours of soft tissues. J Pathol 1972; 107: 27–39.
29. Shah DR, Gaw F, Balderrama DC et al. Malignant giant cell tumor of the soft tissue of the neck. Hospital Physician 2001; 1: 52–5.
30. Sulh MA, Greco MA, Jiang T et al. Proliferation index and vascular density of giant cell tumor of bone: are they prognostic markers? Cancer 1996; 77: 2044–51.
2. Vasil'ev N.V., Mukhamedov M.R., Choinzonov E.L. i dr. Zhamgarian Gigantokletochnye opukholi: obzor literatury. Sib. onkologicheskii zhurn. 2011; 5 (47): 64–9. [in Russian]
3. Konovalenko V.A. Klinika, differentsial'naia diagnostika i stadirovanie sarkom miagkikh tkanei. Prakticheskaia onkologiia. 2005; 5 (4): 32. [in Russian]
4. Chissov V.I, Trakhtenberg A.Kh. Oshibki v klinicheskoi onkologii. Izd. 3-e. M., 2009; 754–68. [in Russian]
5. Аsuquo ME, Nwagbara VI, Agbor C et al. Giant Cell Tumour of Soft Tissue of the Finger: A Case Report. J Clin Exp Oncol 2013; 2: 3.
6. Аngervall L, Hagmar B, Kindblom LG, Merck C. Malignant giant cell tumor of soft tissues: a clinicopathologic, cytologic, ultrastructural, angiographic, and microangiographic study. Cancer 1981; 47: 736–47.
7. Bertoni F, Bacchini P, Staals E. Malignancy in giant cell tumor of bone. Cancer 2003; 97: 2520–9.
8. Brien EW, Mirra JM, Kessler S et al. Benign giant cell tumor of bone with osteosarcomatous transformation (“dedifferentiated” primary malignant GCT): report of two cases. Skeletal Radiol 1997.
9. Chan Y-J, Chao T-K, Chu Y-H, Wang H-W. Giant cell tumor of soft tissue of neck. J Med Sci 2009; 29 (6): 353–5.
10. Dahlin DC, Cupps RE, Johnson EW. Giant cell tumor: a study of 195 cases. Cancer 1970; 25: 1061–70.
11. Shah DR, Gaw F, Balderrama DC et al. Brown Malignant Giant Cell Tumor of the Soft Tissues of the Neck: Case report Hospital Physician January, 2001; p. 52–5.
12. Fletcher CDM, Unni KK, Mertens F eds. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon, France: IARC Press; World Health Organization Classification of Tumours 2002; 5.
13. Folpe AL, Morris RJ, Weiss SW. Soft tissue giant cell tumor of low malignant potential: a proposal for the reclassification of malignant giant cell tumor of soft parts. Mod Pathol 1999; 12: 894–902.
14. Gitelis S, Wang JW, Quast M et al. Recurrence of a giantcell tumor with malignant transformation to a fibrosarcoma twenty-five years after primary treatment. A case report. J Bone Joint Surg Am.
15. Guccion JG, Enzinger FM. Malignant giant cell tumor of soft parts. An analysis of 32 cases. Cancer 1972; 29: 1518–29.
16. Hashimoto K, Hatori M, Hosaka M et al. Osteosarcoma arising from giant cell tumor of bone ten years after primary surgery: a case report and review of the literature. Tohoku J Exp Med 2006; 208: 157–62.
17. Hong S-W, Choi H-Y. Malignant giant cell tumor of the skull. J Korean Neurosurg Soc 2004; 36: 324–7.
18. Hutter RVP, Worcester JN, Francis KC et al. Benign and malignant giant cell tumor of bone. A clinicopathological analysis of the natural history of the disease. Cancer 1962; 15: 653–90.
19. Junior RZB, Camargo OP, Ida CM et al. Primary malignancy in giant cell tumor: a case report. Sao Paulo Med J 2009; 127 (5): 310–3.
20. Junior RZB, Camargo OP, Ida CM et al. Primary malignancy in giant cell tumor: a case report. San Paulo Med J 2009; 127 (5): 310–3.
21. Kumar S, Carter LF. Giant cell tumor of soft tissue of hand: simple but rare diagnosis, which is often missed. Clin Pract 2011; 1: e54.
22. Machinami R, Nishida K, Ishida T et al. Carcinosarcomatousmalignancy, osteosarcoma and squamous cell carcinoma, in giant cell tumor of the right distal femur. Pathol Res Pract 2008; 204.
23. McGrath PJ. Giant-cell tumor of bone: an analysis of fifty two cases. J Bone Joint Surg Br 1972; 54: 216–29.
24. Murphey MD, Nomikos GC, Flemming DJ et al. Imaging of Giant Cell Tumor and Giant Cell Reparative Granuloma of Bone: Radiologic-Pathologic Correlation. Radio Graphics 2001; 21.
25. Nguyen V, Garcia C, Haskell H. Giant cell tumor of soft tissue on the thigh of a 40-year-old woman. Dermatol Online J 2010. 16: 2.
26. Oda Y, Sakamoto A, Saito T et al. Secondary malignant giant-cell tumor of bone: molecular abnormalities of p53 and H-ras gene correlated with malignant transformation. Histopathology 2001; p. 1283–309.
27. Rock MG, Sim FH, Unni KK et al. Secondary malignant giant-cell tumor of bone. Clinicopathological assessment of nineteen patients. J Bone Joint Surg Am 1986; 68: 1073–9.
28. Salm R, Sissons H.A. Giant-cell tumours of soft tissues. J Pathol 1972; 107: 27–39.
29. Shah DR, Gaw F, Balderrama DC et al. Malignant giant cell tumor of the soft tissue of the neck. Hospital Physician 2001; 1: 52–5.
30. Sulh MA, Greco MA, Jiang T et al. Proliferation index and vascular density of giant cell tumor of bone: are they prognostic markers? Cancer 1996; 77: 2044–51.
2. Васильев Н.В., Мухамедов М.Р., Чойнзонов Е.Л. и др. Жамгарян Гигантоклеточные опухоли: обзор литературы. Сиб. онкологический журн. 2011; 5 (47): 64–9. / Vasil'ev N.V., Mukhamedov M.R., Choinzonov E.L. i dr. Zhamgarian Gigantokletochnye opukholi: obzor literatury. Sib. onkologicheskii zhurn. 2011; 5 (47): 64–9. [in Russian]
3. Коноваленко В.А. Клиника, дифференциальная диагностика и стадирование сарком мягких тканей. Практическая онкология. 2005; 5 (4): 32. / Konovalenko V.A. Klinika, differentsial'naia diagnostika i stadirovanie sarkom miagkikh tkanei. Prakticheskaia onkologiia. 2005; 5 (4): 32. [in Russian]
4. Чиссов В.И, Трахтенберг А.Х. Ошибки в клинической онкологии. Изд. 3-е. М., 2009; 754–68. / Chissov V.I, Trakhtenberg A.Kh. Oshibki v klinicheskoi onkologii. Izd. 3-e. M., 2009; 754–68. [in Russian]
5. Аsuquo ME, Nwagbara VI, Agbor C et al. Giant Cell Tumour of Soft Tissue of the Finger: A Case Report. J Clin Exp Oncol 2013; 2: 3.
6. Аngervall L, Hagmar B, Kindblom LG, Merck C. Malignant giant cell tumor of soft tissues: a clinicopathologic, cytologic, ultrastructural, angiographic, and microangiographic study. Cancer 1981; 47: 736–47.
7. Bertoni F, Bacchini P, Staals E. Malignancy in giant cell tumor of bone. Cancer 2003; 97: 2520–9.
8. Brien EW, Mirra JM, Kessler S et al. Benign giant cell tumor of bone with osteosarcomatous transformation (“dedifferentiated” primary malignant GCT): report of two cases. Skeletal Radiol 1997.
9. Chan Y-J, Chao T-K, Chu Y-H, Wang H-W. Giant cell tumor of soft tissue of neck. J Med Sci 2009; 29 (6): 353–5.
10. Dahlin DC, Cupps RE, Johnson EW. Giant cell tumor: a study of 195 cases. Cancer 1970; 25: 1061–70.
11. Shah DR, Gaw F, Balderrama DC et al. Brown Malignant Giant Cell Tumor of the Soft Tissues of the Neck: Case report Hospital Physician January, 2001; p. 52–5.
12. Fletcher CDM, Unni KK, Mertens F eds. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon, France: IARC Press; World Health Organization Classification of Tumours 2002; 5.
13. Folpe AL, Morris RJ, Weiss SW. Soft tissue giant cell tumor of low malignant potential: a proposal for the reclassification of malignant giant cell tumor of soft parts. Mod Pathol 1999; 12: 894–902.
14. Gitelis S, Wang JW, Quast M et al. Recurrence of a giantcell tumor with malignant transformation to a fibrosarcoma twenty-five years after primary treatment. A case report. J Bone Joint Surg Am.
15. Guccion JG, Enzinger FM. Malignant giant cell tumor of soft parts. An analysis of 32 cases. Cancer 1972; 29: 1518–29.
16. Hashimoto K, Hatori M, Hosaka M et al. Osteosarcoma arising from giant cell tumor of bone ten years after primary surgery: a case report and review of the literature. Tohoku J Exp Med 2006; 208: 157–62.
17. Hong S-W, Choi H-Y. Malignant giant cell tumor of the skull. J Korean Neurosurg Soc 2004; 36: 324–7.
18. Hutter RVP, Worcester JN, Francis KC et al. Benign and malignant giant cell tumor of bone. A clinicopathological analysis of the natural history of the disease. Cancer 1962; 15: 653–90.
19. Junior RZB, Camargo OP, Ida CM et al. Primary malignancy in giant cell tumor: a case report. Sao Paulo Med J 2009; 127 (5): 310–3.
20. Junior RZB, Camargo OP, Ida CM et al. Primary malignancy in giant cell tumor: a case report. San Paulo Med J 2009; 127 (5): 310–3.
21. Kumar S, Carter LF. Giant cell tumor of soft tissue of hand: simple but rare diagnosis, which is often missed. Clin Pract 2011; 1: e54.
22. Machinami R, Nishida K, Ishida T et al. Carcinosarcomatousmalignancy, osteosarcoma and squamous cell carcinoma, in giant cell tumor of the right distal femur. Pathol Res Pract 2008; 204.
23. McGrath PJ. Giant-cell tumor of bone: an analysis of fifty two cases. J Bone Joint Surg Br 1972; 54: 216–29.
24. Murphey MD, Nomikos GC, Flemming DJ et al. Imaging of Giant Cell Tumor and Giant Cell Reparative Granuloma of Bone: Radiologic-Pathologic Correlation. Radio Graphics 2001; 21.
25. Nguyen V, Garcia C, Haskell H. Giant cell tumor of soft tissue on the thigh of a 40-year-old woman. Dermatol Online J 2010. 16: 2.
26. Oda Y, Sakamoto A, Saito T et al. Secondary malignant giant-cell tumor of bone: molecular abnormalities of p53 and H-ras gene correlated with malignant transformation. Histopathology 2001; p. 1283–309.
27. Rock MG, Sim FH, Unni KK et al. Secondary malignant giant-cell tumor of bone. Clinicopathological assessment of nineteen patients. J Bone Joint Surg Am 1986; 68: 1073–9.
28. Salm R, Sissons H.A. Giant-cell tumours of soft tissues. J Pathol 1972; 107: 27–39.
29. Shah DR, Gaw F, Balderrama DC et al. Malignant giant cell tumor of the soft tissue of the neck. Hospital Physician 2001; 1: 52–5.
30. Sulh MA, Greco MA, Jiang T et al. Proliferation index and vascular density of giant cell tumor of bone: are they prognostic markers? Cancer 1996; 77: 2044–51.
________________________________________________
2. Vasil'ev N.V., Mukhamedov M.R., Choinzonov E.L. i dr. Zhamgarian Gigantokletochnye opukholi: obzor literatury. Sib. onkologicheskii zhurn. 2011; 5 (47): 64–9. [in Russian]
3. Konovalenko V.A. Klinika, differentsial'naia diagnostika i stadirovanie sarkom miagkikh tkanei. Prakticheskaia onkologiia. 2005; 5 (4): 32. [in Russian]
4. Chissov V.I, Trakhtenberg A.Kh. Oshibki v klinicheskoi onkologii. Izd. 3-e. M., 2009; 754–68. [in Russian]
5. Аsuquo ME, Nwagbara VI, Agbor C et al. Giant Cell Tumour of Soft Tissue of the Finger: A Case Report. J Clin Exp Oncol 2013; 2: 3.
6. Аngervall L, Hagmar B, Kindblom LG, Merck C. Malignant giant cell tumor of soft tissues: a clinicopathologic, cytologic, ultrastructural, angiographic, and microangiographic study. Cancer 1981; 47: 736–47.
7. Bertoni F, Bacchini P, Staals E. Malignancy in giant cell tumor of bone. Cancer 2003; 97: 2520–9.
8. Brien EW, Mirra JM, Kessler S et al. Benign giant cell tumor of bone with osteosarcomatous transformation (“dedifferentiated” primary malignant GCT): report of two cases. Skeletal Radiol 1997.
9. Chan Y-J, Chao T-K, Chu Y-H, Wang H-W. Giant cell tumor of soft tissue of neck. J Med Sci 2009; 29 (6): 353–5.
10. Dahlin DC, Cupps RE, Johnson EW. Giant cell tumor: a study of 195 cases. Cancer 1970; 25: 1061–70.
11. Shah DR, Gaw F, Balderrama DC et al. Brown Malignant Giant Cell Tumor of the Soft Tissues of the Neck: Case report Hospital Physician January, 2001; p. 52–5.
12. Fletcher CDM, Unni KK, Mertens F eds. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon, France: IARC Press; World Health Organization Classification of Tumours 2002; 5.
13. Folpe AL, Morris RJ, Weiss SW. Soft tissue giant cell tumor of low malignant potential: a proposal for the reclassification of malignant giant cell tumor of soft parts. Mod Pathol 1999; 12: 894–902.
14. Gitelis S, Wang JW, Quast M et al. Recurrence of a giantcell tumor with malignant transformation to a fibrosarcoma twenty-five years after primary treatment. A case report. J Bone Joint Surg Am.
15. Guccion JG, Enzinger FM. Malignant giant cell tumor of soft parts. An analysis of 32 cases. Cancer 1972; 29: 1518–29.
16. Hashimoto K, Hatori M, Hosaka M et al. Osteosarcoma arising from giant cell tumor of bone ten years after primary surgery: a case report and review of the literature. Tohoku J Exp Med 2006; 208: 157–62.
17. Hong S-W, Choi H-Y. Malignant giant cell tumor of the skull. J Korean Neurosurg Soc 2004; 36: 324–7.
18. Hutter RVP, Worcester JN, Francis KC et al. Benign and malignant giant cell tumor of bone. A clinicopathological analysis of the natural history of the disease. Cancer 1962; 15: 653–90.
19. Junior RZB, Camargo OP, Ida CM et al. Primary malignancy in giant cell tumor: a case report. Sao Paulo Med J 2009; 127 (5): 310–3.
20. Junior RZB, Camargo OP, Ida CM et al. Primary malignancy in giant cell tumor: a case report. San Paulo Med J 2009; 127 (5): 310–3.
21. Kumar S, Carter LF. Giant cell tumor of soft tissue of hand: simple but rare diagnosis, which is often missed. Clin Pract 2011; 1: e54.
22. Machinami R, Nishida K, Ishida T et al. Carcinosarcomatousmalignancy, osteosarcoma and squamous cell carcinoma, in giant cell tumor of the right distal femur. Pathol Res Pract 2008; 204.
23. McGrath PJ. Giant-cell tumor of bone: an analysis of fifty two cases. J Bone Joint Surg Br 1972; 54: 216–29.
24. Murphey MD, Nomikos GC, Flemming DJ et al. Imaging of Giant Cell Tumor and Giant Cell Reparative Granuloma of Bone: Radiologic-Pathologic Correlation. Radio Graphics 2001; 21.
25. Nguyen V, Garcia C, Haskell H. Giant cell tumor of soft tissue on the thigh of a 40-year-old woman. Dermatol Online J 2010. 16: 2.
26. Oda Y, Sakamoto A, Saito T et al. Secondary malignant giant-cell tumor of bone: molecular abnormalities of p53 and H-ras gene correlated with malignant transformation. Histopathology 2001; p. 1283–309.
27. Rock MG, Sim FH, Unni KK et al. Secondary malignant giant-cell tumor of bone. Clinicopathological assessment of nineteen patients. J Bone Joint Surg Am 1986; 68: 1073–9.
28. Salm R, Sissons H.A. Giant-cell tumours of soft tissues. J Pathol 1972; 107: 27–39.
29. Shah DR, Gaw F, Balderrama DC et al. Malignant giant cell tumor of the soft tissue of the neck. Hospital Physician 2001; 1: 52–5.
30. Sulh MA, Greco MA, Jiang T et al. Proliferation index and vascular density of giant cell tumor of bone: are they prognostic markers? Cancer 1996; 77: 2044–51.
Авторы
Л.Н.Ващенко, С.С.Тодоров, Т.В.Аушева, С.М.Бакулина*, Э.Э.Кечеджиева, С.М.Бабиева
ФГБУ Ростовский научно-исследовательский онкологический институт Минздрава России. 344037, Россия, Ростов-на-Дону, ул. 14-я линия, д. 63
*SMBakulina@gmail.com
Rostov Research Institute of Oncology of the Ministry of Health of the Russian Federation. 344037, Russian Federation, Rostov-on-Don, ul. 14-ia Liniia, d. 63
*SMBakulina@gmail.com
ФГБУ Ростовский научно-исследовательский онкологический институт Минздрава России. 344037, Россия, Ростов-на-Дону, ул. 14-я линия, д. 63
*SMBakulina@gmail.com
________________________________________________
Rostov Research Institute of Oncology of the Ministry of Health of the Russian Federation. 344037, Russian Federation, Rostov-on-Don, ul. 14-ia Liniia, d. 63
*SMBakulina@gmail.com
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