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Осложнения сахарного диабета: современное состояние проблемы
Осложнения сахарного диабета: современное состояние проблемы
Кудина Е.В., Барт Б.Я., Михайлусова М.П., Ларин В.Г. Осложнения сахарного диабета: современное состояние проблемы. Справочник поликлинического врача. 2018; 6: 49–54.
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Аннотация
В статье приводятся основные осложнения сахарного диабета, их патогенез и клиническая значимость. Рассматривается алгоритм обследования пациентов с целью своевременного выявления ангиопатий и нейропатии. Приводятся основные направления в профилактике возникновения и прогрессирования осложнений. Особое внимание уделяется важности самоконтроля пациентами уровня глюкозы крови.
Ключевые слова: сахарный диабет, макроангиопатии, микроангиопатии, нейропатия, диабетическая нефропатия, диабетическая стопа, глюкометрия, гипогликемия.
Key words: diabetes mellitus, macroangiopathy, microangiopathy, neuropathy, diabetic nephropathy, diabetic foot, glucometry, hypoglycemia.
Ключевые слова: сахарный диабет, макроангиопатии, микроангиопатии, нейропатия, диабетическая нефропатия, диабетическая стопа, глюкометрия, гипогликемия.
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Key words: diabetes mellitus, macroangiopathy, microangiopathy, neuropathy, diabetic nephropathy, diabetic foot, glucometry, hypoglycemia.
Полный текст
Список литературы
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5. Wang C, Hess C, Hiatt W, Goldfine A. Clinical Update: Cardiovascular Disease in Diabetes Mellitus: Atherosclerotic Cardiovascular Disease and Heart Failure in Type 2 Diabetes Mellitus – Mechanisms, Management, and Clinical Considerations. Circulation 2016; 133 (24): 2459–502.
6. Sabatine M, Giugliano R, Keec A. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease for the FOURIER Steering Committee and Investigators. N Engl J Med 2017; 376: 1713–22.
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9. Нефрология. Под ред. Е.М.Шилова. М.: ГЭОТАР-Медиа, 2010; с. 432–48. / Nefrologiia. Pod red. E.M.Shilova. M.: GEOTAR-Media, 2010; s. 432–48. [in Russian]
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11. Батрак Г.А., Мясоедова С.Е. Роль самоконтроля гликемии в профилактике диабетических микро- и макрососудистых осложнений. Справочник поликлинического врача. 2017; 3: 59–63. / Batrak G.A., Myasoedova S.E. The role of self-control of glycemia in the prevention of diabetic micro- and macrovascular complications. Handbook for Practitioners Doctors. 2017; 3: 59–62. [in Russian]
12. Patel A, MacMahon S, Chalmers J et al. ADVANCE Collaborative Group. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008; 358 (24): 2560–72.
13. Duckworth W, Abraira C, Moritz T et al. VADT Investigators. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med 2009; 360 (2): 129–39.
14. International Standard EN ISO 15197: 2013. In Vitro diagnostic test systems: Requirements for blood-glucose monitoring systems for self-testing in managing diabetes mellitus. Second Edition 2013-05-15. International Organization for Standardization, 2013; р. 46
15. Caswell M et al. Accuracy and User Performance Evaluation of a Blood Glucose Monitoring System. Diabetes Technol Ther 2015; 3: 152–8.
16. Волкова Е.А., Малыгина О.Ф. Самоконтроль и изменение образа жизни пациентов как важнейшая часть комплексной терапии сахарного диабета типа 2. Справочник поликлинического врача. 2018; 2: 47–52. / Volkova E.A., Malygina O.F. Samokontrol' i izmenenie obraza zhizni patsientov kak vazhneishaia chast' kompleksnoi terapii sakharnogo diabeta tipa 2. Handbook for Practitioners Doctors. 2018; 2: 47–52. [in Russian]
17. World Health Organization. mHealth-New horizons for health through mobile technologies. Global Observatory for eHealth, Volume 3. 2011.
18. IDF Europe position on mobile applications in diabetes. International Diabetes Federation Europe, February 2017.
2. Zhernakova Yu.V., Chazova I.E., Oshchepkova E.V. et al. The prevalence of diabetes mellitus in population of hypertensive patients according to ESSE RF study results. Systemic Hypertension. 2018; 15 (1): 56–62. DOI: 10.26442/2075-082X_15.1.56-62 [in Russian]
3. International Diabetes Federation. IDF Diabetes Atlas, 8th edn. Brussels, Belgium: International Diabetes Federation, 2017. http://www.diabetesatlas.org
4. Seferovic P, Petrie M, Filipatos G et al. Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology. Eur J of Heart Fail 2018; 20 (5): 853–72.
5. Wang C, Hess C, Hiatt W, Goldfine A. Clinical Update: Cardiovascular Disease in Diabetes Mellitus: Atherosclerotic Cardiovascular Disease and Heart Failure in Type 2 Diabetes Mellitus – Mechanisms, Management, and Clinical Considerations. Circulation 2016; 133 (24): 2459–502.
6. Sabatine M, Giugliano R, Keec A. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease for the FOURIER Steering Committee and Investigators. N Engl J Med 2017; 376: 1713–22.
7. Algoritmy spetsializirovannoi meditsinskoi pomoshchi bol'nym sakharnym diabetom. Pod red. I.I.Dedova, M.V.Shestakovoi, A.Iu.Maiorova. Vyp. 8. Sakharnyi diabet. 2017; 20 (1S): 1–112. [in Russian]
8. Niessner A, Tamargo J, Koller L et al. Non-insulin antidiabetic pharmacotherapy in patients with established cardiovascular disease: a position paper of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy. Eur Heart J 2018; 39 (24): 2274–81.
9. Nefrologiia. Pod red. E.M.Shilova. M.: GEOTAR-Media, 2010; s. 432–48. [in Russian]
10. Dedov I.I., Tokmakova A.Iu., Egorova D.N., Galstian G.R. Klinicheskie rekomendatsii po diagnostike i lecheniiu sindroma diabeticheskoi stopy 2015. Mezhdunar. endokrinol. zhurn. 2015; 7 (71): 106–12. [in Russian]
11. Batrak G.A., Myasoedova S.E. The role of self-control of glycemia in the prevention of diabetic micro- and macrovascular complications. Handbook for Practitioners Doctors. 2017; 3: 59–62. [in Russian]
12. Patel A, MacMahon S, Chalmers J et al. ADVANCE Collaborative Group. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008; 358 (24): 2560–72.
13. Duckworth W, Abraira C, Moritz T et al. VADT Investigators. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med 2009; 360 (2): 129–39.
14. International Standard EN ISO 15197: 2013. In Vitro diagnostic test systems: Requirements for blood-glucose monitoring systems for self-testing in managing diabetes mellitus. Second Edition 2013-05-15. International Organization for Standardization, 2013; р. 46
15. Caswell M et al. Accuracy and User Performance Evaluation of a Blood Glucose Monitoring System. Diabetes Technol Ther 2015; 3: 152–8.
16. Volkova E.A., Malygina O.F. Samokontrol' i izmenenie obraza zhizni patsientov kak vazhneishaia chast' kompleksnoi terapii sakharnogo diabeta tipa 2. Handbook for Practitioners Doctors. 2018; 2: 47–52. [in Russian]
17. World Health Organization. mHealth-New horizons for health through mobile technologies. Global Observatory for eHealth, Volume 3. 2011.
18. IDF Europe position on mobile applications in diabetes. International Diabetes Federation Europe, February 2017.
2. Жернакова Ю.В., Чазова И.Е., Ощепкова Е.В. и др. Распространенность сахарного диабета в популяции больных артериальной гипертонией. По данным исследования ЭССЕ-РФ. Системные гипертензии. 2018; 15 (1): 56–62. DOI: 10.26442/2075-082X_15.1.56-62 / Zhernakova Yu.V., Chazova I.E., Oshchepkova E.V. et al. The prevalence of diabetes mellitus in population of hypertensive patients according to ESSE RF study results. Systemic Hypertension. 2018; 15 (1): 56–62. DOI: 10.26442/2075-082X_15.1.56-62 [in Russian]
3. International Diabetes Federation. IDF Diabetes Atlas, 8th edn. Brussels, Belgium: International Diabetes Federation, 2017. http://www.diabetesatlas.org
4. Seferovic P, Petrie M, Filipatos G et al. Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology. Eur J of Heart Fail 2018; 20 (5): 853–72.
5. Wang C, Hess C, Hiatt W, Goldfine A. Clinical Update: Cardiovascular Disease in Diabetes Mellitus: Atherosclerotic Cardiovascular Disease and Heart Failure in Type 2 Diabetes Mellitus – Mechanisms, Management, and Clinical Considerations. Circulation 2016; 133 (24): 2459–502.
6. Sabatine M, Giugliano R, Keec A. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease for the FOURIER Steering Committee and Investigators. N Engl J Med 2017; 376: 1713–22.
7. Алгоритмы специализированной медицинской помощи больным сахарным диабетом. Под ред. И.И.Дедова, М.В.Шестаковой, А.Ю.Майорова. Вып. 8. Сахарный диабет. 2017; 20 (1S): 1–112. / Algoritmy spetsializirovannoi meditsinskoi pomoshchi bol'nym sakharnym diabetom. Pod red. I.I.Dedova, M.V.Shestakovoi, A.Iu.Maiorova. Vyp. 8. Sakharnyi diabet. 2017; 20 (1S): 1–112. [in Russian]
8. Niessner A, Tamargo J, Koller L et al. Non-insulin antidiabetic pharmacotherapy in patients with established cardiovascular disease: a position paper of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy. Eur Heart J 2018; 39 (24): 2274–81.
9. Нефрология. Под ред. Е.М.Шилова. М.: ГЭОТАР-Медиа, 2010; с. 432–48. / Nefrologiia. Pod red. E.M.Shilova. M.: GEOTAR-Media, 2010; s. 432–48. [in Russian]
10. Дедов И.И., Токмакова А.Ю., Егорова Д.Н., Галстян Г.Р. Клинические рекомендации по диагностике и лечению синдрома диабетической стопы 2015. Междунар. эндокринол. журн. 2015; 7 (71): 106–12. / Dedov I.I., Tokmakova A.Iu., Egorova D.N., Galstian G.R. Klinicheskie rekomendatsii po diagnostike i lecheniiu sindroma diabeticheskoi stopy 2015. Mezhdunar. endokrinol. zhurn. 2015; 7 (71): 106–12. [in Russian]
11. Батрак Г.А., Мясоедова С.Е. Роль самоконтроля гликемии в профилактике диабетических микро- и макрососудистых осложнений. Справочник поликлинического врача. 2017; 3: 59–63. / Batrak G.A., Myasoedova S.E. The role of self-control of glycemia in the prevention of diabetic micro- and macrovascular complications. Handbook for Practitioners Doctors. 2017; 3: 59–62. [in Russian]
12. Patel A, MacMahon S, Chalmers J et al. ADVANCE Collaborative Group. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008; 358 (24): 2560–72.
13. Duckworth W, Abraira C, Moritz T et al. VADT Investigators. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med 2009; 360 (2): 129–39.
14. International Standard EN ISO 15197: 2013. In Vitro diagnostic test systems: Requirements for blood-glucose monitoring systems for self-testing in managing diabetes mellitus. Second Edition 2013-05-15. International Organization for Standardization, 2013; р. 46
15. Caswell M et al. Accuracy and User Performance Evaluation of a Blood Glucose Monitoring System. Diabetes Technol Ther 2015; 3: 152–8.
16. Волкова Е.А., Малыгина О.Ф. Самоконтроль и изменение образа жизни пациентов как важнейшая часть комплексной терапии сахарного диабета типа 2. Справочник поликлинического врача. 2018; 2: 47–52. / Volkova E.A., Malygina O.F. Samokontrol' i izmenenie obraza zhizni patsientov kak vazhneishaia chast' kompleksnoi terapii sakharnogo diabeta tipa 2. Handbook for Practitioners Doctors. 2018; 2: 47–52. [in Russian]
17. World Health Organization. mHealth-New horizons for health through mobile technologies. Global Observatory for eHealth, Volume 3. 2011.
18. IDF Europe position on mobile applications in diabetes. International Diabetes Federation Europe, February 2017.
________________________________________________
2. Zhernakova Yu.V., Chazova I.E., Oshchepkova E.V. et al. The prevalence of diabetes mellitus in population of hypertensive patients according to ESSE RF study results. Systemic Hypertension. 2018; 15 (1): 56–62. DOI: 10.26442/2075-082X_15.1.56-62 [in Russian]
3. International Diabetes Federation. IDF Diabetes Atlas, 8th edn. Brussels, Belgium: International Diabetes Federation, 2017. http://www.diabetesatlas.org
4. Seferovic P, Petrie M, Filipatos G et al. Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology. Eur J of Heart Fail 2018; 20 (5): 853–72.
5. Wang C, Hess C, Hiatt W, Goldfine A. Clinical Update: Cardiovascular Disease in Diabetes Mellitus: Atherosclerotic Cardiovascular Disease and Heart Failure in Type 2 Diabetes Mellitus – Mechanisms, Management, and Clinical Considerations. Circulation 2016; 133 (24): 2459–502.
6. Sabatine M, Giugliano R, Keec A. Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease for the FOURIER Steering Committee and Investigators. N Engl J Med 2017; 376: 1713–22.
7. Algoritmy spetsializirovannoi meditsinskoi pomoshchi bol'nym sakharnym diabetom. Pod red. I.I.Dedova, M.V.Shestakovoi, A.Iu.Maiorova. Vyp. 8. Sakharnyi diabet. 2017; 20 (1S): 1–112. [in Russian]
8. Niessner A, Tamargo J, Koller L et al. Non-insulin antidiabetic pharmacotherapy in patients with established cardiovascular disease: a position paper of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy. Eur Heart J 2018; 39 (24): 2274–81.
9. Nefrologiia. Pod red. E.M.Shilova. M.: GEOTAR-Media, 2010; s. 432–48. [in Russian]
10. Dedov I.I., Tokmakova A.Iu., Egorova D.N., Galstian G.R. Klinicheskie rekomendatsii po diagnostike i lecheniiu sindroma diabeticheskoi stopy 2015. Mezhdunar. endokrinol. zhurn. 2015; 7 (71): 106–12. [in Russian]
11. Batrak G.A., Myasoedova S.E. The role of self-control of glycemia in the prevention of diabetic micro- and macrovascular complications. Handbook for Practitioners Doctors. 2017; 3: 59–62. [in Russian]
12. Patel A, MacMahon S, Chalmers J et al. ADVANCE Collaborative Group. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008; 358 (24): 2560–72.
13. Duckworth W, Abraira C, Moritz T et al. VADT Investigators. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med 2009; 360 (2): 129–39.
14. International Standard EN ISO 15197: 2013. In Vitro diagnostic test systems: Requirements for blood-glucose monitoring systems for self-testing in managing diabetes mellitus. Second Edition 2013-05-15. International Organization for Standardization, 2013; р. 46
15. Caswell M et al. Accuracy and User Performance Evaluation of a Blood Glucose Monitoring System. Diabetes Technol Ther 2015; 3: 152–8.
16. Volkova E.A., Malygina O.F. Samokontrol' i izmenenie obraza zhizni patsientov kak vazhneishaia chast' kompleksnoi terapii sakharnogo diabeta tipa 2. Handbook for Practitioners Doctors. 2018; 2: 47–52. [in Russian]
17. World Health Organization. mHealth-New horizons for health through mobile technologies. Global Observatory for eHealth, Volume 3. 2011.
18. IDF Europe position on mobile applications in diabetes. International Diabetes Federation Europe, February 2017.
Авторы
Е.В.Кудина*, Б.Я.Барт, М.П.Михайлусова, В.Г.Ларин
ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России. 117997, Россия, Москва, ул. Островитянова, д. 1
*kudina@mail.ru
N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1
*kudina@mail.ru
ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России. 117997, Россия, Москва, ул. Островитянова, д. 1
*kudina@mail.ru
________________________________________________
N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1
*kudina@mail.ru
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