Метастатическое поражение правого предсердия почечно-клеточной карциномой
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Isaev G.O., Mironova O.Yu., Yudakova M.E., et al. Metastatic lesion of the right atrium with renal cell carcinoma. Therapeutic Archive. 2019; 91 (9): 124–128. DOI: 10.26442/00403660.2019.09.000218
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Ключевые слова: почечно-клеточная карцинома, ЭхоКГ-диагностика метастазов, КТ-диагностика метастазов, диагностика метастазов в сердце.
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Tumors in the heart are rare and difficult to diagnose pathologies. There are primary and secondary tumors, the letter tumors include metastases of other tumors. In this work is presented clinical case of metastatic lesion of the right atrium with renal cell carcinoma. Modern methods of diagnostics of patients with intracardiac formations are discussed.
Keywords: renal cell carcinoma, echocardiography diagnosis of metastases, CT diagnosis of metastases, diagnosis of heart metastases.
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7. Tamin S, Maleszewski J, Scott C, et al. Prognostic and Bioepidemiologic Implications of Papillary Fibroelastomas. J Am Coll Cardiol. 2015;65 (22):2420-9. doi: 10.1016/j.jacc.2015.03.569
8. Fleischmann K, Schiller N. Papillary Fibroelastoma. J Am Coll Cardiol. 2015;65(22):2430-2. doi: 10.1016/j.jacc.2015.04.021
9. Hillenbrand T, Menge F, Hohenberger P, Kasper B. Primary and secondary angiosarcomas: a comparative single-center analysis. Clin Sarcoma Res. 2015;5(1). doi: 10.1186/s13569-015-0028-9
10. Sharma A, DeValeria P, Scherber R, et al. Angiosarcoma Causing Cardiac Constriction Late after Radiation Therapy for Breast Carcinoma. Tex Heart Inst J. 2016;43(1):81-3. doi: 10.14503/thij-14-4549
11. Calvete O, Martinez P, Garcia-Pavia P, et al. A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li–Fraumeni-like families. Nat Commun. 2015;6(1). doi: 10.1038/ncom ms9383
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20. Bussani R, De-Giorgio F, Abbate A, Silvestri F. Cardiac metastases. J Clin Pathol. 2007;60(1):27-34. doi: 10.1136/jcp.2005.035105
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27. Kupsky D, Newman D, Kumar G, Maleszewski J, Edwards W, Klarich K. Echocardiographic Features of Cardiac Angiosarcomas: The Mayo Clinic Experience (1976-2013). Echocardiography. 2015;33(2):186-92. doi: 10. 1111/echo.13060
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29. Matsumura M, Takamoto S, Kyo S, Yokote Y, Omoto R. Advantages of transesophageal color Doppler echocardiography in the diagnosis and surgical treatment of cardiac masses. J Cardiol. 1990;20(3):701-14.
30. Goldman J, Foster E. Transesophageal Echocardiographic (TEE) Evaluation of Intracardiac and Pericardial Masses. Cardiol Clin. 2000;18 (4):849-60. doi: 10.1016/s0733-8651(05)70184-3
31. Leibowitz G, Keller N, Daniel W, et al. Transesophageal versus transthoracic echocardiography in the evaluation of right atrial tumors. Am Heart J. 1995;130(6):1224-7. doi: 10.1016/0002-8703(95)90146-9
32. Lestuzzi C. Primary tumors of the heart. Curr Opin Cardiol. 2016;31 (6):593-8. doi: 10.1097/hco.0000000000000335
33. Chaloupka J, Fishman E, Siegelman S. Use of CT in the evaluation of primary cardiac tumors. Cardiovasc Intervent Radiol. 1986;9(3):132-5. doi: 10.1007/bf02577921
34. Gross B, Glazer G, Francis I. CT of intracardiac and intrapericardial masses. Am J Roentgenology. 1983;140(5):903-7. doi: 10.2214/ajr.140.5.9 03
35. Funari M, Fujita N, Peck W, Higgins C. Cardiac Tumors. J Comput Assist Tomogr. 1991;15(6):953-8. doi: 10.1097/00004728-199111000-00009
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37. Chow W, Chow T, Tai Y, Yip A, Cheung K. Angiographic visualization of ‘tumour vascularity’ in atrial myxoma. Eur Heart J. 1991;12(1):79-82. doi: 10.1093/oxfordjournals.eurheartj.a059829
38. Azzalini L, de Hemptinne Q, Asgar A, Ibrahim R. Right atrial mass in a patient with breast cancer: percutaneous transcatheter biopsy under intracardiac echocardiography guidance. BMJ Case Rep. 2016:bcr20162 15146. doi: 10.1136/bcr-2016-215146
39. Reddy G, Maor E, Rihal C, et al. P6104Percutaneous transcatheter biopsy for intracardiac mass diagnosis. Eur Heart J. 2017;38(suppl 1). doi: 10. 1093/eurheartj/ehx493.p6104
40. Kuppahally S, Litwin S, Michaels A. Endomyocardial Biopsy of Right Atrial Angiosarcoma Guided by Intracardiac Echocardiography. Cardiol Res Pract. 2010;2010:1-2. doi: 10.4061/2010/681726
41. Клинические рекомендации Министерства здравоохранения Российской Федерации. Метастазы злокачественных опухолей без выявленного первичного очага. 2017 [Clinical recommendations of the Ministry of Health of the Russian Federation. Metastases of malignant tumors without an identified primary focus. 2017 (In Russ.)].
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1. [Storozhakov GI. Tumors of the heart. Journal Heart failure. 2008;9(4):194-201 (In Russ.)].
2. Reynen K. Metastases to the heart. Annals of Oncology. 2004;15(3):375-81. doi: 10.1093/annonc/mdh086
3. [Gubar' LM, Miklashevich FS, Gorbach OA. Radiation diagnosis of heart tumors. 2017 (In Russ.)].
4. Travis W, Brambilla E, Muller-Hermelink H. World Health Organization Classification Of Tumours. Lyon: IARC Publications, 2005.
5. Travis W, Brambilla E, Burke A, Marx A, Nicholson A. Introduction to The 2015 World Health Organization Classification of Tumors of the Lung, Pleura, Thymus, and Heart. J Thoracic Oncology. 2015;10(9):1240-2. doi: 10.1097/jto.0000000000000663
6. Butany J, Nair V, Naseemuddin A, Nair G, Catton C, Yau T. Cardiac tumours: diagnosis and management. The Lancet Oncology. 2005;6(4): 219-28. doi: 10.1016/s1470-2045(05)70093-0
7. Tamin S, Maleszewski J, Scott C, et al. Prognostic and Bioepidemiologic Implications of Papillary Fibroelastomas. J Am Coll Cardiol. 2015;65 (22):2420-9. doi: 10.1016/j.jacc.2015.03.569
8. Fleischmann K, Schiller N. Papillary Fibroelastoma. J Am Coll Cardiol. 2015;65(22):2430-2. doi: 10.1016/j.jacc.2015.04.021
9. Hillenbrand T, Menge F, Hohenberger P, Kasper B. Primary and secondary angiosarcomas: a comparative single-center analysis. Clin Sarcoma Res. 2015;5(1). doi: 10.1186/s13569-015-0028-9
10. Sharma A, DeValeria P, Scherber R, et al. Angiosarcoma Causing Cardiac Constriction Late after Radiation Therapy for Breast Carcinoma. Tex Heart Inst J. 2016;43(1):81-3. doi: 10.14503/thij-14-4549
11. Calvete O, Martinez P, Garcia-Pavia P, et al. A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li–Fraumeni-like families. Nat Commun. 2015;6(1). doi: 10.1038/ncom ms9383
12. Butany J, Nair V, Naseemuddin A, Nair G, Catton C, Yau T. Cardiac tumours: diagnosis and management. The Lancet Oncology. 2005;6(4): 219-28. doi: 10.1016/s1470-2045(05)70093-0
13. Pinho T, Rodrigues-Pereira P, Araújo V, Oliveira NP, Macedo F, Graça A, Maciel MJ. Cardiac metastasis of melanoma as first manifestation of disease. Revista portuguesa de cardiologia: orgao oficial da Sociedade Portuguesa de Cardiologia= Portuguese journal of cardiology: an official journal of the Portuguese Society of Cardiology. 2009;28(5):633-9. doi: 10.5216/ree.v11.46894
14. Cheruvu B, Cheruvu P, Boyars M. An unusual case of metastasis to the left side of the heart: a case report. J Med Case Rep. 2011;5(1). doi: 10. 1186/1752-1947-5-23
15. Goldberg A, Blankstein R, Padera R. Tumors Metastatic to the Heart. Circulation. 2013;128(16):1790-4. doi: 10.1161/circulationaha.112.00 0790
16. [Konradi YV, Ryzhkova DV. Cardiac tumors imaging. Translational Medicine. 2015;2(4):28-40 (In Russ.)]. doi: 10.18705/2311-4495-2015-0-4-28-40
17. Aburto J, Bruckner BA, Blackmon SH, Beyer EA, Reardon MJ. Renal Cell Carcinoma, Metastatic to the Left Ventricle. Texas Heart Institute J. 2009;36(1):48-9.
18. Meng Q, Lai H, Lima J, Tong W, Qian Y, Lai S. Echocardiographic and pathological characteristics of cardiac metastasis in patients with lymphoma. Oncol Rep. 2002. doi: 10.3892/or.9.1.85
19. Gross B, Glazer G, Francis I. CT of intracardiac and intrapericardial masses. Am J Roentgenology. 1983;140(5):903-7. doi: 10.2214/ajr.140. 5.903
20. Bussani R, De-Giorgio F, Abbate A, Silvestri F. Cardiac metastases. J Clin Pathol. 2007;60(1):27-34. doi: 10.1136/jcp.2005.035105
21. Funari M, Fujita N, Peck W, Higgins C. Cardiac Tumors. J Comput Assist Tomogr. 1991;15(6):953-8. doi: 10.1097/00004728-199111000-00009
22.[Paratsii AZ. An Unusual case of a lesion of the right ventricle of the heart with a malignant tumor. Oncology. 2018;20(1):48 (In Russ.)].
23. Cresti A, Chiavarelli M, Glauber M et al. Incidence rate of primary cardiac tumors. J Cardiovascular Medicine. 2016;17(1):37-43. doi: 10.2459/jcm.0000000000000059
24. Isogai T, Yasunaga H, Matsui H, Tanaka H, Hisagi M, Fushimi K. Factors affecting in-hospital mortality and likelihood of undergoing surgical resection in patients with primary cardiac tumors. J Cardiol. 2017;69(1):287-92. doi: 10.1016/j.jjcc.2016.05.008
25. Ekmektzoglou K, Samelis G, Xanthos T. Heart and tumors: location, metastasis, clinical manifestations, diagnostic approaches and therapeutic considerations. J Cardiovascular Medicine. 2008;9(8):769-77. doi: 10.2459/jcm.0b013e3282f88e49
26. Roberts W. Neoplasms Involving the Heart, Their Simulators, and Adverse Consequences of Their Therapy. Baylor University Medical Center Proceedings. 2001;14(4):358-76. doi: 10.1080/08998280.2001. 11927789
27. Kupsky D, Newman D, Kumar G, Maleszewski J, Edwards W, Klarich K. Echocardiographic Features of Cardiac Angiosarcomas: The Mayo Clinic Experience (1976-2013). Echocardiography. 2015;33(2):186-92. doi: 10. 1111/echo.13060
28. Alam M, Rosman H, Grullon C. Transesophageal Echocardiography in Evaluation of Atrial Masses. Angiology. 1995;46(2):123-8. doi: 10.1177/ 000331979504600205
29. Matsumura M, Takamoto S, Kyo S, Yokote Y, Omoto R. Advantages of transesophageal color Doppler echocardiography in the diagnosis and surgical treatment of cardiac masses. J Cardiol. 1990;20(3):701-14.
30. Goldman J, Foster E. Transesophageal Echocardiographic (TEE) Evaluation of Intracardiac and Pericardial Masses. Cardiol Clin. 2000;18 (4):849-60. doi: 10.1016/s0733-8651(05)70184-3
31. Leibowitz G, Keller N, Daniel W, et al. Transesophageal versus transthoracic echocardiography in the evaluation of right atrial tumors. Am Heart J. 1995;130(6):1224-7. doi: 10.1016/0002-8703(95)90146-9
32. Lestuzzi C. Primary tumors of the heart. Curr Opin Cardiol. 2016;31 (6):593-8. doi: 10.1097/hco.0000000000000335
33. Chaloupka J, Fishman E, Siegelman S. Use of CT in the evaluation of primary cardiac tumors. Cardiovasc Intervent Radiol. 1986;9(3):132-5. doi: 10.1007/bf02577921
34. Gross B, Glazer G, Francis I. CT of intracardiac and intrapericardial masses. Am J Roentgenology. 1983;140(5):903-7. doi: 10.2214/ajr.140.5.9 03
35. Funari M, Fujita N, Peck W, Higgins C. Cardiac Tumors. J Comput Assist Tomogr. 1991;15(6):953-8. doi: 10.1097/00004728-199111000-00009
36. Gulati G, Sharma S, Kothari S, Juneja R, Saxena A, Talwar K. Comparison of Echo and MRI in the Imaging Evaluation of Intracardiac Masses. Cardiovasc Intervent Radiol. 2004;27(5). doi: 10.1007/s00270-004-0123-4
37. Chow W, Chow T, Tai Y, Yip A, Cheung K. Angiographic visualization of ‘tumour vascularity’ in atrial myxoma. Eur Heart J. 1991;12(1):79-82. doi: 10.1093/oxfordjournals.eurheartj.a059829
38. Azzalini L, de Hemptinne Q, Asgar A, Ibrahim R. Right atrial mass in a patient with breast cancer: percutaneous transcatheter biopsy under intracardiac echocardiography guidance. BMJ Case Rep. 2016:bcr20162 15146. doi: 10.1136/bcr-2016-215146
39. Reddy G, Maor E, Rihal C, et al. P6104Percutaneous transcatheter biopsy for intracardiac mass diagnosis. Eur Heart J. 2017;38(suppl 1). doi: 10. 1093/eurheartj/ehx493.p6104
40. Kuppahally S, Litwin S, Michaels A. Endomyocardial Biopsy of Right Atrial Angiosarcoma Guided by Intracardiac Echocardiography. Cardiol Res Pract. 2010;2010:1-2. doi: 10.4061/2010/681726
41. [Clinical recommendations of the Ministry of Health of the Russian Federation. Metastases of malignant tumors without an identified primary focus. 2017 (In Russ.)].
1Ф ГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет), Москва, Россия;
2 Многопрофильный медицинский центр Банка России, Москва, Россия;
3 ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России, Москва, Россия
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G.O. Isaev 1, O.Yu. Mironova 1, M.E. Yudakova 2, R.M. Shakhnovish 3, V.V. Fomin 1
1 Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia;
2 Hospital of the Central Bank of the Russian Federation, Moscow, Russia;
3 National Medical Research Center of Cardiology, Moscow, Russia