Новые возможности ренальной денервации

Агаева Р.А., Данилов Н.М., Щелкова Г.В. и др. Новые возможности ренальной денервации. Терапевтический архив. 2020; 92 (6): 84–88.
DOI: 10.26442/00403660.2020.06.000588

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Agaeva R.A., Danilov N.M., Shelkova G.V., et al. Therapeutic Archive. 2020; 92 (6): 84–88. DOI: 10.26442/00403660.2020.06.000588

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Аннотация

Около 10 лет назад радиочастотная денервация почечных артерий представлена как метод малоинвазивного лечения резистентной артериальной гипертонии. Первые исследования продемонстрировали эффективность данной процедуры, что привело к растущему интересу в этой области и быстрому развитию данного метода. Тем не менее результаты первого рандомизированного исследования SYMPLICITY HTN-3 поставили под сомнение роль радиочастотной денервации в лечении резистентной артериальной гипертонии. Данный факт привел к снижению класса рекомендации и уровню доказательности в клинических рекомендациях Европейского общества кардиологов и Европейского общества по гипертонии в 2018 г. Сегодня в медицинском сообществе активно обсуждают результаты недавно опубликованных исследований, таких как SPYRAL HTN-OFF MED, SPYRAL HTN-ON MED, RADIANCE-HTN SOLO и RADIOSOUND-HTN.

Ключевые слова: артериальная гипертония, почечные артерии, ренальная денервация, мультиэлектродное устройство.

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Radiofrequency renal artery denervation (RND) was introduced as a method of interventional treatment of resistant hypertension almost ten years ago. The first studies demonstrated the effectiveness of this procedure. This has led to growing interest in this area and the rapid development of the method. However, the results of the first randomized trial of SYMPLICITY HTN-3 questioned the role of RND in the treatment of resistant hypertension, this fact conducted to the decrease in the recommendation class and level of evidence in the Guidelines of the European Society of Cardiology and the European Society of Hypertension in 2018. To date, the medical community is actively discussing the results of recently published trials such as SPYRAL HTN-OFF MED, SPYRAL HTN-ON MED, RADIANCE-HTN SOLO and RADIOSOUND-HTN.

Keywords: hypertension, renal artery, renal denervation, multi-electrode catheter.

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Авторы

Р.А. Агаева, Н.М. Данилов, Г.В. Щелкова, Ю.Г. Матчин, И.Е. Чазова

Институт клинической кардиологии им. А.Л. Мясникова ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России, Москва, Россия

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R.A. Agaeva, N.M. Danilov, G.V. Shelkova, U.G. Matchin, I.Е. Chazova

Myasnikov Institute of Clinical Cardiology, National Medical Research Center of Cardiology, Moscow, Russia

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