Приверженность и эффективность длительной ПАП-терапии у пациентов с нарушениями дыхания во время сна, ассоциированными с нарушениями проводимости сердца
Приверженность и эффективность длительной ПАП-терапии у пациентов с нарушениями дыхания во время сна, ассоциированными с нарушениями проводимости сердца
Елфимова Е.М., Михайлова О.О., Хачатрян Н.Т. и др. Приверженность и эффективность длительной ПАП-терапии у пациентов с нарушениями дыхания во время сна, ассоциированными с нарушениями проводимости сердца. Терапевтический архив. 2020; 92 (9): 39–43. DOI: 10.26442/00403660.2020.09.000730
DOI: 10.26442/00403660.2020.09.000730
________________________________________________
DOI: 10.26442/00403660.2020.09.000730
Материалы доступны только для специалистов сферы здравоохранения. Авторизуйтесь или зарегистрируйтесь.
Аннотация
Цель. Оценить эффективность ПАП-терапии (терапия путем создания положительного давления в дыхательных путях) в устранении нарушений дыхания во время сна и ассоциированных нарушений проводимости сердца при длительном использовании.
Материалы и методы. В исследование включен 21 пациент, проходивший обследование в ИКК им. А.Л. Мясникова ФГБУ «НМИЦ кардиологии» по поводу нарушений ритма и проводимости сердца, а также нарушений дыхания во время сна и находившийся на ПАП-терапии более 12 мес. Средний возраст составил 66,5 [63,5; 73,2] года, индекс массы тела – 33,0 [30,2; 38,5] кг/м2, индекс апноэ-гипопноэ сна – 65,0 [59,0; 86,3] соб/ч. На момент анализа 15 пациентов продолжали использование ПАП-терапии (среднее время использования составило 6,0 года [4,7; 9,2]), и 6 человек отказались от ее длительного применения, среднее время использования ПАП-терапии до момента отказа составило 2,8±2,1 года.
Результаты. На фоне ПАП-терапии выявлено стойкое снижение индекса апноэ-гипопноэ сна с 63,6 до 3,7 соб/ч (р=0,0002). Критериям приверженности ПАП-терапии (использование более 4 ч за ночь, более 70% ночей) соответствовали 86% пациентов. Исходно до назначения ПАП-терапии все нарушения проводимости сердца выражались в развитии «остановок» сердца во время сна и превышали 3 с при колебаниях от 3,1 и до 10,6 с. На фоне ПАП-терапии асистолии длительностью свыше 3 с не зафиксировано.
Заключение. При лечении пациентов с синдромом обструктивного апноэ сна в сочетании с ночными нарушениями проводимости сердца эффект ПАП-терапии сохраняется в условиях многолетнего применения и при хорошей приверженности данному виду лечения.
Ключевые слова: синдром обструктивного апноэ сна, ПАП-терапия, нарушения проводимости сердца, длительное использование, приверженность.
Materials and methods. We included 21 patients who were examined at the Myasnikov Institute of Clinical Cardiology, National Medical Research Center of Cardiology, regarding cardiac rhythm and conduction disturbances, as well as obstructive sleep apnea and who have been on PAP therapy for more than 12 months. The average age was 66.5 [63.5; 73.2] years, body mass index – 33.0 [30.2; 38.5] kg/m2, apnea-hypopnea index – 65.0 [59.0; 86.3]/h. At the time of analysis, 15 patients continued to use PAP therapy (mean time of use: 6.0 years [4.7; 9.2]) and 6 patients refused long-term use of PAP therapy, mean time to use PAP therapy until failure amounted to 2.8±2.1 years.
Results. PAP therapy lead to a persistent decrease in apnea-hypopnea index of 63.6/h to 3.7/h was (p=0.0002). 86% of patients met the criteria for adherence to PAP therapy (use >4 hours/night, more than 70% of nights). Initially, before the use of PAP therapy, all cardiac conduction disorders were during sleep and exceeded 3 seconds, with fluctuations from 3.1 to 10.6 seconds. PAP therapy appeared to be effective in all patients: no asystoles, duration of more than 3 seconds, were detected.
Conclusion. In obstructive sleep apnea patients with concomitant nighttime cardiac conduction disturbances, the long-term use of PAP therapy is effective and with good adherence.
Keywords: obstructive sleep apnea syndrome, PAP therapy, cardiac conduction disorders, long-term use, adherence.
Материалы и методы. В исследование включен 21 пациент, проходивший обследование в ИКК им. А.Л. Мясникова ФГБУ «НМИЦ кардиологии» по поводу нарушений ритма и проводимости сердца, а также нарушений дыхания во время сна и находившийся на ПАП-терапии более 12 мес. Средний возраст составил 66,5 [63,5; 73,2] года, индекс массы тела – 33,0 [30,2; 38,5] кг/м2, индекс апноэ-гипопноэ сна – 65,0 [59,0; 86,3] соб/ч. На момент анализа 15 пациентов продолжали использование ПАП-терапии (среднее время использования составило 6,0 года [4,7; 9,2]), и 6 человек отказались от ее длительного применения, среднее время использования ПАП-терапии до момента отказа составило 2,8±2,1 года.
Результаты. На фоне ПАП-терапии выявлено стойкое снижение индекса апноэ-гипопноэ сна с 63,6 до 3,7 соб/ч (р=0,0002). Критериям приверженности ПАП-терапии (использование более 4 ч за ночь, более 70% ночей) соответствовали 86% пациентов. Исходно до назначения ПАП-терапии все нарушения проводимости сердца выражались в развитии «остановок» сердца во время сна и превышали 3 с при колебаниях от 3,1 и до 10,6 с. На фоне ПАП-терапии асистолии длительностью свыше 3 с не зафиксировано.
Заключение. При лечении пациентов с синдромом обструктивного апноэ сна в сочетании с ночными нарушениями проводимости сердца эффект ПАП-терапии сохраняется в условиях многолетнего применения и при хорошей приверженности данному виду лечения.
Ключевые слова: синдром обструктивного апноэ сна, ПАП-терапия, нарушения проводимости сердца, длительное использование, приверженность.
________________________________________________
Materials and methods. We included 21 patients who were examined at the Myasnikov Institute of Clinical Cardiology, National Medical Research Center of Cardiology, regarding cardiac rhythm and conduction disturbances, as well as obstructive sleep apnea and who have been on PAP therapy for more than 12 months. The average age was 66.5 [63.5; 73.2] years, body mass index – 33.0 [30.2; 38.5] kg/m2, apnea-hypopnea index – 65.0 [59.0; 86.3]/h. At the time of analysis, 15 patients continued to use PAP therapy (mean time of use: 6.0 years [4.7; 9.2]) and 6 patients refused long-term use of PAP therapy, mean time to use PAP therapy until failure amounted to 2.8±2.1 years.
Results. PAP therapy lead to a persistent decrease in apnea-hypopnea index of 63.6/h to 3.7/h was (p=0.0002). 86% of patients met the criteria for adherence to PAP therapy (use >4 hours/night, more than 70% of nights). Initially, before the use of PAP therapy, all cardiac conduction disorders were during sleep and exceeded 3 seconds, with fluctuations from 3.1 to 10.6 seconds. PAP therapy appeared to be effective in all patients: no asystoles, duration of more than 3 seconds, were detected.
Conclusion. In obstructive sleep apnea patients with concomitant nighttime cardiac conduction disturbances, the long-term use of PAP therapy is effective and with good adherence.
Keywords: obstructive sleep apnea syndrome, PAP therapy, cardiac conduction disorders, long-term use, adherence.
Список литературы
1. Namtvedt SK, Randby A, Einvik G, et al. Cardiac arrhythmias in obstructive sleep apnea (from the Akershus sleep apnea project). Am J Cardiol. 2011;108:1141-6. doi: 10.1016/j.amjcard.2011.06.016
2. Stradling JR, Crosby JH. Predictors and prevalence of obstructive sleep apnoea and snoring in 1001 middle aged men. Thorax. 1991;46:85-90. doi: 10.1136/thx.46.2.85
3. Camen G, Clarenbach CF, Stöwhas AC, et al. The effects of simulated obstructive apnea and hypopnea on arrhythmic potential in healthy subjects. Eur J Appl Physiol. 2013;113:489-96. doi: 10.1007/s00421-012-2457-y
4. Patil SP, Ayappa IA, Caples SM, et al. Treatment of adult obstructive sleep apnea with positive airway pressure: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2019;15(2):335-43. doi: 10.5664/jcsm.7638
5. Tilkian AG, Guilleminault C, Schroeder JS, et al. Sleep-induced apnea syndrome. Prevalence of cardiac arrhythmias and their reversal after tracheostomy. Am J Med. 1977;63:348-58. doi: 10.1016/0002-9343(77)90272-8
6. Becker HF, Koehler U, Stammnitz A, et al. Heart block in patients with sleep apnoea. Thorax. 1998;53(Suppl. 3):S29-S32. doi: 10.1136/thx.53.2008.s29
7. Zwillich C, Devlin T, White D, et al. Bradycardia during sleep apnea. Characteristics and mechanism. J Clin Invest. 1982;69:1286-92. doi: 10.1172/jci110568
8. Hersi AS. Obstructive sleep apnea and cardiac arrhythmias. Ann Thorac Med. 2010;5:10-7. doi: 10.4103/1817-1737.58954
9. Kusumoto FM, Schoenfeld MH, Barrett C, et al. 2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society. J Am Coll Cardiol. 2018;8. doi: 10.1016/j.jacc.2018.10.043
10. Becker HF, Brandenburg U, Peter JH, et al. Reversal of sinus arrest and atrioventricular conduction block in patients with sleep apnoea during nasal continuous positive airway pressure. Am J Respir Crit Care Med. 1995;151:215-8. doi: 10.1164/ajrccm.151.1.7812557
11. Simantirakis N, Schiza SI, Marketou ME, et al. Severe bradyarrhythmias in patients with sleep apnoea: the effect of continuous positive airway pressure treatment. A long-term evaluation using an insertable loop recorder. Eur Heart J. 2004;25:1070-6. doi: 10.1016/j.ehj.2004.04.017
12. Dziewas R, Imai T, Dittrich R, et al. Night-time bradyarrhythmia in a patient with mild obstructive sleep apnea syndrome is reversed with CPAP treatment. J Clin Sleep Med. 2006;2:454-7. doi: 10.5664/jcsm.26663
13. Grimm W, Koehler U, Fus E, et al. Outcome of patients with sleep apnoea-associated severe bradyarrhythmias after continuous positive airway pressure treatment. Am J Cardiol. 2000;86:688-92. doi: 10.1016/S0002-9149(00)01055-9
14. Harbison J, O'Reilly P, Mc Nicholas WT. Cardiac rhythm disturbances in the obstructive sleep apnoea syndrome. Effects of nasal continuous positive airway pressure treatment. Chest. 2000;118:591-5. doi: 10.1378/chest.118.3.591
15. Abe H, Takahashi M, Yaegashi H, et al. Efficacy of continuous positive airway pressure on arrhythmias in obstructive sleep apnea patients. Heart Vessels. 2010;25:63-9. doi: 10.1007/s00380-009-1164-z
16. Centers for Medicare and Medicaid Services website. Decision Memo for Continuous Positive Airway Pressure (CPAP) Therapy for Obstructive Sleep Apnea (OSA) (CAG-00093N).
17. Xu Wu, Zilong Liu, Su Chi Chang, et al. Screening and managing obstructive sleep apnoea in nocturnal heart block patients: an observational study. Respir Res. 2016;17:16. doi: 10.1186/s12931-016-0333-8
19. Курлыкина Н.В., Певзнер А.В., Литвин А.Ю. и др. Возможности лечения больных с длительными ночными асистолиями и синдром обструктивного апноэ сна созданием постоянного положительного давления воздуха в верхних дыхательных путях. Кардиология. 2009;49(6):36-42. eLIBRARY ID: 16536288 [Kurlykina AV, Pevzner AYu, Litvin, et al. Possibilities of treatment of patients with long nocturnal asystoles and obstructive sleep apnea syndrome by creating constant positive air pressure in upper respiratory tract. Cardiology. 2009;49(6):36-42 (In Russ.)].
20. DiMatteo MR. Variations in patients' adherence to medical recommendations: a quantitative review of 50 years of research. Med Care. 2004;42(3):200-9. doi: 10.1097/01.mlr.0000114908.90348.f9
21. Toy EL, Beaulieu NU, Mchale JM, et al. Treatment of COPD: relationships between daily dosing frequency, adherence, resource use, and costs. Respir Med. 2011;105(3):435-41. doi: 10.1016/j.rmed.2010.09.006
22. Sawyer AM, Gooneratne NS, Marcus CL, et al. A systematic
review of CPAP adherence across age groups: clinical and
empiric insights for developing CPAP adherence interventions,
Sleep Med Rev. 2011;15(6):343-56. Epub 2011 Jun 8. doi: 10.1016/j.smrv.2011.01.003
23. Weaver TE, Grunstein RR. Adherence to continuous positive airway pressure therapy: the challenge to effective treatment. Proc Am Thorac Soc. 2008;5(2):173. doi: 10.1513/pats.200708-119MG
24. Gay P, Weaver T, Loube D, Iber C, Evaluation of positive airway pressure treatment for sleep related breathing disorders in adults. Positive Airway Pressure Task Force, Standards of Practice Committee, American Academy of Sleep Medicine. Sleep. 2006;29(3):381. doi: 10.1093/sleep/29.3.381
25. Berry RB, Kushida CA, Kryger MH, et al. Respiratory event detection by a positive airway pressure device. Sleep. 2012;35(3):361. Epub 2012 Mar 1. doi: 10.5665/sleep.1696
2. Stradling JR, Crosby JH. Predictors and prevalence of obstructive sleep apnoea and snoring in 1001 middle aged men. Thorax. 1991;46:85-90. doi: 10.1136/thx.46.2.85
3. Camen G, Clarenbach CF, Stöwhas AC, et al. The effects of simulated obstructive apnea and hypopnea on arrhythmic potential in healthy subjects. Eur J Appl Physiol. 2013;113:489-96. doi: 10.1007/s00421-012-2457-y
4. Patil SP, Ayappa IA, Caples SM, et al. Treatment of adult obstructive sleep apnea with positive airway pressure: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2019;15(2):335-43. doi: 10.5664/jcsm.7638
5. Tilkian AG, Guilleminault C, Schroeder JS, et al. Sleep-induced apnea syndrome. Prevalence of cardiac arrhythmias and their reversal after tracheostomy. Am J Med. 1977;63:348-58. doi: 10.1016/0002-9343(77)90272-8
6. Becker HF, Koehler U, Stammnitz A, et al. Heart block in patients with sleep apnoea. Thorax. 1998;53(Suppl. 3):S29-S32. doi: 10.1136/thx.53.2008.s29
7. Zwillich C, Devlin T, White D, et al. Bradycardia during sleep apnea. Characteristics and mechanism. J Clin Invest. 1982;69:1286-92. doi: 10.1172/jci110568
8. Hersi AS. Obstructive sleep apnea and cardiac arrhythmias. Ann Thorac Med. 2010;5:10-7. doi: 10.4103/1817-1737.58954
9. Kusumoto FM, Schoenfeld MH, Barrett C, et al. 2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society. J Am Coll Cardiol. 2018;8. doi: 10.1016/j.jacc.2018.10.043
10. Becker HF, Brandenburg U, Peter JH, et al. Reversal of sinus arrest and atrioventricular conduction block in patients with sleep apnoea during nasal continuous positive airway pressure. Am J Respir Crit Care Med. 1995;151:215-8. doi: 10.1164/ajrccm.151.1.7812557
11. Simantirakis N, Schiza SI, Marketou ME, et al. Severe bradyarrhythmias in patients with sleep apnoea: the effect of continuous positive airway pressure treatment. A long-term evaluation using an insertable loop recorder. Eur Heart J. 2004;25:1070-6. doi: 10.1016/j.ehj.2004.04.017
12. Dziewas R, Imai T, Dittrich R, et al. Night-time bradyarrhythmia in a patient with mild obstructive sleep apnea syndrome is reversed with CPAP treatment. J Clin Sleep Med. 2006;2:454-7. doi: 10.5664/jcsm.26663
13. Grimm W, Koehler U, Fus E, et al. Outcome of patients with sleep apnoea-associated severe bradyarrhythmias after continuous positive airway pressure treatment. Am J Cardiol. 2000;86:688-92. doi: 10.1016/S0002-9149(00)01055-9
14. Harbison J, O'Reilly P, Mc Nicholas WT. Cardiac rhythm disturbances in the obstructive sleep apnoea syndrome. Effects of nasal continuous positive airway pressure treatment. Chest. 2000;118:591-5. doi: 10.1378/chest.118.3.591
15. Abe H, Takahashi M, Yaegashi H, et al. Efficacy of continuous positive airway pressure on arrhythmias in obstructive sleep apnea patients. Heart Vessels. 2010;25:63-9. doi: 10.1007/s00380-009-1164-z
16. Centers for Medicare and Medicaid Services website. Decision Memo for Continuous Positive Airway Pressure (CPAP) Therapy for Obstructive Sleep Apnea (OSA) (CAG-00093N).
17. Xu Wu, Zilong Liu, Su Chi Chang, et al. Screening and managing obstructive sleep apnoea in nocturnal heart block patients: an observational study. Respir Res. 2016;17:16. doi: 10.1186/s12931-016-0333-8
19. Курлыкина Н.В., Певзнер А.В., Литвин А.Ю. и др. Возможности лечения больных с длительными ночными асистолиями и синдром обструктивного апноэ сна созданием постоянного положительного давления воздуха в верхних дыхательных путях. Кардиология. 2009;49(6):36-42. eLIBRARY ID: 16536288 [Kurlykina AV, Pevzner AYu, Litvin, et al. Possibilities of treatment of patients with long nocturnal asystoles and obstructive sleep apnea syndrome by creating constant positive air pressure in upper respiratory tract. Cardiology. 2009;49(6):36-42 (In Russ.)].
20. DiMatteo MR. Variations in patients' adherence to medical recommendations: a quantitative review of 50 years of research. Med Care. 2004;42(3):200-9. doi: 10.1097/01.mlr.0000114908.90348.f9
21. Toy EL, Beaulieu NU, Mchale JM, et al. Treatment of COPD: relationships between daily dosing frequency, adherence, resource use, and costs. Respir Med. 2011;105(3):435-41. doi: 10.1016/j.rmed.2010.09.006
22. Sawyer AM, Gooneratne NS, Marcus CL, et al. A systematic
review of CPAP adherence across age groups: clinical and
empiric insights for developing CPAP adherence interventions,
Sleep Med Rev. 2011;15(6):343-56. Epub 2011 Jun 8. doi: 10.1016/j.smrv.2011.01.003
23. Weaver TE, Grunstein RR. Adherence to continuous positive airway pressure therapy: the challenge to effective treatment. Proc Am Thorac Soc. 2008;5(2):173. doi: 10.1513/pats.200708-119MG
24. Gay P, Weaver T, Loube D, Iber C, Evaluation of positive airway pressure treatment for sleep related breathing disorders in adults. Positive Airway Pressure Task Force, Standards of Practice Committee, American Academy of Sleep Medicine. Sleep. 2006;29(3):381. doi: 10.1093/sleep/29.3.381
25. Berry RB, Kushida CA, Kryger MH, et al. Respiratory event detection by a positive airway pressure device. Sleep. 2012;35(3):361. Epub 2012 Mar 1. doi: 10.5665/sleep.1696
2. Stradling JR, Crosby JH. Predictors and prevalence of obstructive sleep apnoea and snoring in 1001 middle aged men. Thorax. 1991;46:85-90. doi: 10.1136/thx.46.2.85
3. Camen G, Clarenbach CF, Stöwhas AC, et al. The effects of simulated obstructive apnea and hypopnea on arrhythmic potential in healthy subjects. Eur J Appl Physiol. 2013;113:489-96. doi: 10.1007/s00421-012-2457-y
4. Patil SP, Ayappa IA, Caples SM, et al. Treatment of adult obstructive sleep apnea with positive airway pressure: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2019;15(2):335-43. doi: 10.5664/jcsm.7638
5. Tilkian AG, Guilleminault C, Schroeder JS, et al. Sleep-induced apnea syndrome. Prevalence of cardiac arrhythmias and their reversal after tracheostomy. Am J Med. 1977;63:348-58. doi: 10.1016/0002-9343(77)90272-8
6. Becker HF, Koehler U, Stammnitz A, et al. Heart block in patients with sleep apnoea. Thorax. 1998;53(Suppl. 3):S29-S32. doi: 10.1136/thx.53.2008.s29
7. Zwillich C, Devlin T, White D, et al. Bradycardia during sleep apnea. Characteristics and mechanism. J Clin Invest. 1982;69:1286-92. doi: 10.1172/jci110568
8. Hersi AS. Obstructive sleep apnea and cardiac arrhythmias. Ann Thorac Med. 2010;5:10-7. doi: 10.4103/1817-1737.58954
9. Kusumoto FM, Schoenfeld MH, Barrett C, et al. 2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society. J Am Coll Cardiol. 2018;8. doi: 10.1016/j.jacc.2018.10.043
10. Becker HF, Brandenburg U, Peter JH, et al. Reversal of sinus arrest and atrioventricular conduction block in patients with sleep apnoea during nasal continuous positive airway pressure. Am J Respir Crit Care Med. 1995;151:215-8. doi: 10.1164/ajrccm.151.1.7812557
11. Simantirakis N, Schiza SI, Marketou ME, et al. Severe bradyarrhythmias in patients with sleep apnoea: the effect of continuous positive airway pressure treatment. A long-term evaluation using an insertable loop recorder. Eur Heart J. 2004;25:1070-6. doi: 10.1016/j.ehj.2004.04.017
12. Dziewas R, Imai T, Dittrich R, et al. Night-time bradyarrhythmia in a patient with mild obstructive sleep apnea syndrome is reversed with CPAP treatment. J Clin Sleep Med. 2006;2:454-7. doi: 10.5664/jcsm.26663
13. Grimm W, Koehler U, Fus E, et al. Outcome of patients with sleep apnoea-associated severe bradyarrhythmias after continuous positive airway pressure treatment. Am J Cardiol. 2000;86:688-92. doi: 10.1016/S0002-9149(00)01055-9
14. Harbison J, O'Reilly P, Mc Nicholas WT. Cardiac rhythm disturbances in the obstructive sleep apnoea syndrome. Effects of nasal continuous positive airway pressure treatment. Chest. 2000;118:591-5. doi: 10.1378/chest.118.3.591
15. Abe H, Takahashi M, Yaegashi H, et al. Efficacy of continuous positive airway pressure on arrhythmias in obstructive sleep apnea patients. Heart Vessels. 2010;25:63-9. doi: 10.1007/s00380-009-1164-z
16. Centers for Medicare and Medicaid Services website. Decision Memo for Continuous Positive Airway Pressure (CPAP) Therapy for Obstructive Sleep Apnea (OSA) (CAG-00093N).
17. Xu Wu, Zilong Liu, Su Chi Chang, et al. Screening and managing obstructive sleep apnoea in nocturnal heart block patients: an observational study. Respir Res. 2016;17:16. doi: 10.1186/s12931-016-0333-8
19. Курлыкина Н.В., Певзнер А.В., Литвин А.Ю. и др. Возможности лечения больных с длительными ночными асистолиями и синдром обструктивного апноэ сна созданием постоянного положительного давления воздуха в верхних дыхательных путях. Кардиология. 2009;49(6):36-42. eLIBRARY ID: 16536288 [Kurlykina AV, Pevzner AYu, Litvin, et al. Possibilities of treatment of patients with long nocturnal asystoles and obstructive sleep apnea syndrome by creating constant positive air pressure in upper respiratory tract. Cardiology. 2009;49(6):36-42 (In Russ.)].
20. DiMatteo MR. Variations in patients' adherence to medical recommendations: a quantitative review of 50 years of research. Med Care. 2004;42(3):200-9. doi: 10.1097/01.mlr.0000114908.90348.f9
21. Toy EL, Beaulieu NU, Mchale JM, et al. Treatment of COPD: relationships between daily dosing frequency, adherence, resource use, and costs. Respir Med. 2011;105(3):435-41. doi: 10.1016/j.rmed.2010.09.006
22. Sawyer AM, Gooneratne NS, Marcus CL, et al. A systematic
review of CPAP adherence across age groups: clinical and
empiric insights for developing CPAP adherence interventions,
Sleep Med Rev. 2011;15(6):343-56. Epub 2011 Jun 8. doi: 10.1016/j.smrv.2011.01.003
23. Weaver TE, Grunstein RR. Adherence to continuous positive airway pressure therapy: the challenge to effective treatment. Proc Am Thorac Soc. 2008;5(2):173. doi: 10.1513/pats.200708-119MG
24. Gay P, Weaver T, Loube D, Iber C, Evaluation of positive airway pressure treatment for sleep related breathing disorders in adults. Positive Airway Pressure Task Force, Standards of Practice Committee, American Academy of Sleep Medicine. Sleep. 2006;29(3):381. doi: 10.1093/sleep/29.3.381
25. Berry RB, Kushida CA, Kryger MH, et al. Respiratory event detection by a positive airway pressure device. Sleep. 2012;35(3):361. Epub 2012 Mar 1. doi: 10.5665/sleep.1696
________________________________________________
2. Stradling JR, Crosby JH. Predictors and prevalence of obstructive sleep apnoea and snoring in 1001 middle aged men. Thorax. 1991;46:85-90. doi: 10.1136/thx.46.2.85
3. Camen G, Clarenbach CF, Stöwhas AC, et al. The effects of simulated obstructive apnea and hypopnea on arrhythmic potential in healthy subjects. Eur J Appl Physiol. 2013;113:489-96. doi: 10.1007/s00421-012-2457-y
4. Patil SP, Ayappa IA, Caples SM, et al. Treatment of adult obstructive sleep apnea with positive airway pressure: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2019;15(2):335-43. doi: 10.5664/jcsm.7638
5. Tilkian AG, Guilleminault C, Schroeder JS, et al. Sleep-induced apnea syndrome. Prevalence of cardiac arrhythmias and their reversal after tracheostomy. Am J Med. 1977;63:348-58. doi: 10.1016/0002-9343(77)90272-8
6. Becker HF, Koehler U, Stammnitz A, et al. Heart block in patients with sleep apnoea. Thorax. 1998;53(Suppl. 3):S29-S32. doi: 10.1136/thx.53.2008.s29
7. Zwillich C, Devlin T, White D, et al. Bradycardia during sleep apnea. Characteristics and mechanism. J Clin Invest. 1982;69:1286-92. doi: 10.1172/jci110568
8. Hersi AS. Obstructive sleep apnea and cardiac arrhythmias. Ann Thorac Med. 2010;5:10-7. doi: 10.4103/1817-1737.58954
9. Kusumoto FM, Schoenfeld MH, Barrett C, et al. 2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society. J Am Coll Cardiol. 2018;8. doi: 10.1016/j.jacc.2018.10.043
10. Becker HF, Brandenburg U, Peter JH, et al. Reversal of sinus arrest and atrioventricular conduction block in patients with sleep apnoea during nasal continuous positive airway pressure. Am J Respir Crit Care Med. 1995;151:215-8. doi: 10.1164/ajrccm.151.1.7812557
11. Simantirakis N, Schiza SI, Marketou ME, et al. Severe bradyarrhythmias in patients with sleep apnoea: the effect of continuous positive airway pressure treatment. A long-term evaluation using an insertable loop recorder. Eur Heart J. 2004;25:1070-6. doi: 10.1016/j.ehj.2004.04.017
12. Dziewas R, Imai T, Dittrich R, et al. Night-time bradyarrhythmia in a patient with mild obstructive sleep apnea syndrome is reversed with CPAP treatment. J Clin Sleep Med. 2006;2:454-7. doi: 10.5664/jcsm.26663
13. Grimm W, Koehler U, Fus E, et al. Outcome of patients with sleep apnoea-associated severe bradyarrhythmias after continuous positive airway pressure treatment. Am J Cardiol. 2000;86:688-92. doi: 10.1016/S0002-9149(00)01055-9
14. Harbison J, O'Reilly P, Mc Nicholas WT. Cardiac rhythm disturbances in the obstructive sleep apnoea syndrome. Effects of nasal continuous positive airway pressure treatment. Chest. 2000;118:591-5. doi: 10.1378/chest.118.3.591
15. Abe H, Takahashi M, Yaegashi H, et al. Efficacy of continuous positive airway pressure on arrhythmias in obstructive sleep apnea patients. Heart Vessels. 2010;25:63-9. doi: 10.1007/s00380-009-1164-z
16. Centers for Medicare and Medicaid Services website. Decision Memo for Continuous Positive Airway Pressure (CPAP) Therapy for Obstructive Sleep Apnea (OSA) (CAG-00093N).
17. Xu Wu, Zilong Liu, Su Chi Chang, et al. Screening and managing obstructive sleep apnoea in nocturnal heart block patients: an observational study. Respir Res. 2016;17:16. doi: 10.1186/s12931-016-0333-8
19. Курлыкина Н.В., Певзнер А.В., Литвин А.Ю. и др. Возможности лечения больных с длительными ночными асистолиями и синдром обструктивного апноэ сна созданием постоянного положительного давления воздуха в верхних дыхательных путях. Кардиология. 2009;49(6):36-42. eLIBRARY ID: 16536288 [Kurlykina AV, Pevzner AYu, Litvin, et al. Possibilities of treatment of patients with long nocturnal asystoles and obstructive sleep apnea syndrome by creating constant positive air pressure in upper respiratory tract. Cardiology. 2009;49(6):36-42 (In Russ.)].
20. DiMatteo MR. Variations in patients' adherence to medical recommendations: a quantitative review of 50 years of research. Med Care. 2004;42(3):200-9. doi: 10.1097/01.mlr.0000114908.90348.f9
21. Toy EL, Beaulieu NU, Mchale JM, et al. Treatment of COPD: relationships between daily dosing frequency, adherence, resource use, and costs. Respir Med. 2011;105(3):435-41. doi: 10.1016/j.rmed.2010.09.006
22. Sawyer AM, Gooneratne NS, Marcus CL, et al. A systematic
review of CPAP adherence across age groups: clinical and
empiric insights for developing CPAP adherence interventions,
Sleep Med Rev. 2011;15(6):343-56. Epub 2011 Jun 8. doi: 10.1016/j.smrv.2011.01.003
23. Weaver TE, Grunstein RR. Adherence to continuous positive airway pressure therapy: the challenge to effective treatment. Proc Am Thorac Soc. 2008;5(2):173. doi: 10.1513/pats.200708-119MG
24. Gay P, Weaver T, Loube D, Iber C, Evaluation of positive airway pressure treatment for sleep related breathing disorders in adults. Positive Airway Pressure Task Force, Standards of Practice Committee, American Academy of Sleep Medicine. Sleep. 2006;29(3):381. doi: 10.1093/sleep/29.3.381
25. Berry RB, Kushida CA, Kryger MH, et al. Respiratory event detection by a positive airway pressure device. Sleep. 2012;35(3):361. Epub 2012 Mar 1. doi: 10.5665/sleep.1696
Авторы
Е.М. Елфимова1, О.О. Михайлова1, Н.Т. Хачатрян1, А.Ю. Литвин1,2, И.Е. Чазова1, Л.Ю. Лайович1, Т.А. Малкина1, А.В. Певзнер1, С.П. Голицын1
1 Институт клинической кардиологии им. А.Л. Мясникова ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России, Москва, Россия;
2 ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России, Москва, Россия
1 Myasnikov Institute of Clinical Cardiology, National Medical Research Center of Cardiology, Moscow, Russia;
2 Pirogov Russian National Research Medical University, Moscow, Russia
1 Институт клинической кардиологии им. А.Л. Мясникова ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России, Москва, Россия;
2 ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России, Москва, Россия
________________________________________________
1 Myasnikov Institute of Clinical Cardiology, National Medical Research Center of Cardiology, Moscow, Russia;
2 Pirogov Russian National Research Medical University, Moscow, Russia
Цель портала OmniDoctor – предоставление профессиональной информации врачам, провизорам и фармацевтам.