1. Black CJ, Houghton LA, Ford AC. Insights into the evaluation and management of dyspepsia: recent developments and new guidelines. Therap Adv Gastroenterol. 2018;11:1756284818805597. DOI:10.1177/1756284818805597
2. Ford AC, Marwaha A, Sood R, Moayyedi P. Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis. Gut. 2015;64(7):1049-57.
DOI:10.1136/gutjnl-2014-307843
3. Moayyedi P, Talley NJ, Fennerty MB, Vakil N. Can the clinical history distinguish between organic and functional dyspepsia? JAMA. 2006;295(13):1566-76. DOI:10.1001/jama.295.13.1566
4. Stanghellini V, Chan FKL, Hasler WL, et al. Gastroduodenal Disorders. Gastroenterology. 2016;150(6):1380-92. DOI:10.1053/j.gastro.2016.02.011
5. Moayyedi P, Lacy BE, Andrews CN, et al. ACG and CAG Clinical Guideline: Management of Dyspepsia. Am J Gastroenterol. 2017;112(7):988-1013. DOI:10.1038/ajg.2017.154
6. Dugan K, Ablah E, Okut H, et al. Guideline Adherence in Dyspepsia Investigation and Treatment. Kans J Med. 2020;13:306-10. DOI:10.17161/kjm.vol13.13838
7. Miwa H, Kusano M, Arisawa T, et al. Evidence-based clinical practice guidelines for functional dyspepsia. J Gastroenterol. 2015;50(2):125-39. 
DOI:10.1007/s00535-014-1022-3
8. Bisschops R, Karamanolis G, Arts J, et al. Relationship between symptoms and ingestion of a meal in functional dyspepsia. Gut. 2008;57(11):1495-503. DOI:10.1136/gut.2007.137125
9. McBride D, Hardoon S, Walters K, et al. Explaining variation in referral from primary to secondary care: cohort study. BMJ. 2010;341:c6267. DOI:10.1136/bmj.c6267
10. Lacy BE, Weiser KT, Kennedy AT, et al. Functional dyspepsia: the economic impact to patients. Aliment Pharmacol Ther. 2013;38(2):170-7. DOI:10.1111/apt.12355
11. Harer KN, Hasler WL. Functional Dyspepsia: A Review of the Symptoms, Evaluation, and Treatment Options. Gastroenterol Hepatol (N Y). 2020;16(2):66-74. 
12. Парфенов А.И., Ахмадуллина О.В., Белостоцкий Н.И., и др. Энтеропатия с нарушением мембранного пищеварения и перспективы цитопротективной терапии. Терапевтический архив. 2021;93(2):129-37 
[Parfenov AI, Akhmadullina OV, Belostotsky NI, et al. Enteropathy with impaired membrane digestion and the prospects for cytoprotective therapy. Terapevticheskii Arkhiv (Ter. Arkh.). 2021;93(2):129-37 (in Russian)]. DOI:10.26442/00403660.2021.02.200602
13. Aro P, Talley NJ, Agréus L, et al. Functional dyspepsia impairs quality of life in the adult population. Aliment Pharmacol Ther. 2011;33(11):1215-24.
DOI:10.1111/j.1365-2036.2011.04640.x
14. Wang C, Fang X. Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia. J Neurogastroenterol Motil. 2021;27(2):153-64. DOI:10.5056/jnm20175
15. Talley NJ, Ford AC. Functional Dyspepsia. N Engl J Med. 2015;373(19):1853-63. DOI:10.1056/NEJMra1501505
16. Walker MM, Aggarwal KR, Shim LS, et al. Duodenal eosinophilia and early satiety in functional dyspepsia: confirmation of a positive association in an Australian cohort. J Gastroenterol Hepatol. 2014;29(3):474-9. DOI:10.1111/jgh.12419
17. Wauters L, Dickman R, Drug V, et al. United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia. United European Gastroenterol J. 2021;9(3):307-31. DOI:10.1002/ueg2.12061
18. National Institute for Health and Care Excellence. Dyspepsia and Gastro‑oesophageal Reflux Disease in Adults. Quality Standard QS96. London: NICE, 2015.
19. Futagami S, Itoh T, Sakamoto C. Systematic review with meta-analysis: post-infectious functional dyspepsia. Aliment Pharmacol Ther. 2015;41(2):177-88. DOI:10.1111/apt.13006
20. Meeroff JC, Schreiber DS, Trier JS, Blacklow NR. Abnormal gastric motor function in viral gastroenteritis. Ann Intern Med. 1980;92(3):370-3. 
DOI:10.7326/0003-4819-92-3-370
21. Stanzel RDP, Lourenssen S, Blennerhassett MG. Inflammation causes expression of NGF in epithelial cells of the rat colon. Exp Neurol. 2008;211(1):203-13. DOI:10.1016/j.expneurol.2008.01.028
22. Demir IE, Schäfer KH, Tieftrunk E, et al. Neural plasticity in the gastrointestinal tract: chronic inflammation, neurotrophic signals, and hypersensitivity. Acta Neuropathol. 2013;125(4):491-509. DOI:10.1007/s00401-013-1099-4
23. Depoortere I. Taste receptors of the gut: emerging roles in health and disease. Gut. 2014;63(1):179-90. DOI:10.1136/gutjnl-2013-305112
24. Van den Houte K, Scarpellini E, Verbeure W, et al. The Role of GI Peptides in Functional Dyspepsia and Gastroparesis: A Systematic Review. Front Psychiatry. 2020;11:172. DOI:10.3389/fpsyt.2020.00172
25. Miwa H. Why dyspepsia can occur without organic disease: pathogenesis and management of functional dyspepsia. J Gastroenterol. 2012;47(8):862-71.
DOI:10.1007/s00535-012-0625-9
26. Camilleri M, Dubois D, Coulie B, et al. Prevalence and socioeconomic impact of upper gastrointestinal disorders in the United States: results of the US Upper Gastrointestinal Study. Clin Gastroenterol Hepatol. 2005;3(6):543-52.
DOI:10.1016/s1542-3565(05)00153-9
27. Vakil N, Talley N, van Zanten SV, et al. Cost of detecting malignant lesions by endoscopy in 2741 primary care dyspeptic patients without alarm symptoms. Clin Gastroenterol Hepatol. 2009;7(7):756-61. DOI:10.1016/j.cgh.2009.03.031
28. Oh JH, Kwon JG, Jung HK, et al. Clinical Practice Guidelines for Functional Dyspepsia in Korea. J Neurogastroenterol Motil. 2020;26(1):29-50. 
DOI:10.5056/jnm19209
29. Lee MJ, Jung HK, Lee KE, et al. Degranulated Eosinophils Contain More Fine Nerve Fibers in the Duodenal Mucosa of Patients With Functional Dyspepsia. J Neurogastroenterol Motil. 2019;25(2):212-21. DOI:10.5056/jnm18176
30. Moayyedi P, Mason J. Clinical and economic consequences of dyspepsia in the community. Gut. 2002;50(Suppl. 4):iv10-2. DOI:10.1136/gut.50.suppl_4.iv1
31. Camilleri M, Parkman HP, Shafi MA, et al.; American College of Gastroenterology. Clinical guideline: management of gastroparesis. Am J Gastroenterol. 2013;108(1):18-37; quiz 38. DOI:10.1038/ajg.2012.373
32. Sarnelli G, Caenepeel P, Geypens B, et al. Symptoms associated with impaired gastric emptying of solids and liquids in functional dyspepsia. Am J Gastroenterol. 2003;98(4):783-8. DOI:10.1111/j.1572-0241.2003.07389.x
33. Ford AC, Bercik P, Morgan DG, et al. The Rome III criteria for the diagnosis of functional dyspepsia in secondary care are not superior to previous definitions. Gastroenterology. 2014;146(4):932-40; quiz e14-5. 
DOI:10.1053/j.gastro.2014.01.014
34. Wang YP, Herndon CC, Lu CL. Non-pharmacological Approach in the Management of Functional Dyspepsia. J Neurogastroenterol Motil. 2020;26(1):6-15. DOI:10.5056/jnm19005
35. Pinto-Sanchez MI, Yuan Y, Hassan A, et al. Proton pump inhibitors for functional dyspepsia. Cochrane Database Syst Rev. 2017;11:CD011194. DOI:10.1002/14651858.CD011194.pub
36. Yamawaki H, Futagami S, Wakabayashi M, et al. Management of functional dyspepsia: state of the art and emerging therapies. Ther Adv Chronic Dis. 2018;9(1):23-32. DOI:10.1177/2040622317725479
37. Sonnenberg A, Lash RH, Genta RM. A national study of Helicobactor pylori infection in gastric biopsy specimens. Gastroenterology. 2010;139(6):1894-901.e2; quiz e12. DOI:10.1053/j.gastro.2010.08.018
38. Sugano K, Tack J, Kuipers EJ, et al. Kyoto global consensus report on Helicobacter pylori gastritis. Gut. 2015;64(9):1353-67. DOI:10.1136/gutjnl-2015-309252
39. Tack J, Janssen P, Masaoka T, et al. Efficacy of buspirone, a fundus-relaxing drug, in patients with functional dyspepsia. Clin Gastroenterol Hepatol. 2012;10(11):1239-45. DOI:10.1016/j.cgh.2012.06.036
40. Vakil N, Halling K, Ohlsson L, Wernersson B. Symptom overlap between postprandial distress and epigastric pain syndromes of the Rome III dyspepsia classification. Am J Gastroenterol. 2013;108(5):767-74. DOI:10.1038/ajg.2013.89
41. Ford AC, Luthra P, Tack J, et al. Efficacy of psychotropic drugs in functional dyspepsia: systematic review and meta-analysis. Gut. 2017;66(3):411-20.
DOI:10.1136/gutjnl-2015-310721
42. National Institute for Health and Care Excellence. Gastro-Oesophageal Reflux Disease and Dyspepsia in Adults: Investigation and Management. Clinical Guideline CG184. London: NICE, 2014.
43. Ивашкин В.Т., Маев И.В., Шептулин А.А., и др. Клинические рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению функциональной диспепсии. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2017;27(1):50-61 [Ivashkin VT, Mayev IV, Sheptulin AA, et al. Diagnosis and treatment of the functional dyspepsia: clinical guidelines of the Russian Gastroenterological Association. Rossijskij zhurnal gastroenterologii, gepatologii, koloproktologii. 2017;27(1):50-61 (in Russian)].
DOI:10.22416/1382-4376-2017-27-1-50-61
44. Drossman DA. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV. Gastroenterology. 2016:S0016-5085(16)00223-7. DOI:10.1053/j.gastro.2016.02.032
45. Bang CS, Kim JH, Baik GH, et al. Mosapride treatment for functional dyspepsia: a meta-analysis. J Gastroenterol Hepatol. 2015;30(1):28-42. 
DOI:10.1111/jgh.12662
46. Quigley EMM. Cisapride: what can we learn from the rise and fall of a prokinetic? J Dig Dis. 2011;12(3):147-56. DOI:10.1111/j.1751-2980.2011.00491.x
47. Doggrell SA, Hancox JC. Cardiac safety concerns for domperidone, an antiemetic and prokinetic, and galactogogue medicine. Expert Opin Drug Saf. 2014;13(1):131-8. DOI:10.1517/14740338.2014.851193
48. Yang YJ, Bang CS, Baik GH, et al. Prokinetics for the treatment of functional dyspepsia: Bayesian network meta-analysis. BMC Gastroenterol. 2017;17(1):83.
DOI:10.1186/s12876-017-0639-0
49. Al Quraan AM, Beriwal N, Sangay P, Namgyal T. The Psychotic Impact of Helicobacter pylori Gastritis and Functional Dyspepsia on Depression: A Systematic Review. Cureus. 2019;11(10):e5956. DOI:10.7759/cureus.5956
50. Карева Е.Н., Сереброва С.Ю. Медикаментозное лечение нарушений моторики желудка – проблемы, пути решения, достижения. Экспериментальная и клиническая гастроэнтерология. 2017;143(7):167-83 [Kareva EN, Serebrova SYu. Challenges in drug treatment of gastric motility disorders. Eksperimental'naya i klinicheskaya gastroenterologiya. 2017;143(7):167-83 (in Russian)].

________________________________________________

1. Black CJ, Houghton LA, Ford AC. Insights into the evaluation and management of dyspepsia: recent developments and new guidelines. Therap Adv Gastroenterol. 2018;11:1756284818805597. DOI:10.1177/1756284818805597
2. Ford AC, Marwaha A, Sood R, Moayyedi P. Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis. Gut. 2015;64(7):1049-57.
DOI:10.1136/gutjnl-2014-307843
3. Moayyedi P, Talley NJ, Fennerty MB, Vakil N. Can the clinical history distinguish between organic and functional dyspepsia? JAMA. 2006;295(13):1566-76. DOI:10.1001/jama.295.13.1566
4. Stanghellini V, Chan FKL, Hasler WL, et al. Gastroduodenal Disorders. Gastroenterology. 2016;150(6):1380-92. DOI:10.1053/j.gastro.2016.02.011
5. Moayyedi P, Lacy BE, Andrews CN, et al. ACG and CAG Clinical Guideline: Management of Dyspepsia. Am J Gastroenterol. 2017;112(7):988-1013. DOI:10.1038/ajg.2017.154
6. Dugan K, Ablah E, Okut H, et al. Guideline Adherence in Dyspepsia Investigation and Treatment. Kans J Med. 2020;13:306-10. DOI:10.17161/kjm.vol13.13838
7. Miwa H, Kusano M, Arisawa T, et al. Evidence-based clinical practice guidelines for functional dyspepsia. J Gastroenterol. 2015;50(2):125-39. 
DOI:10.1007/s00535-014-1022-3
8. Bisschops R, Karamanolis G, Arts J, et al. Relationship between symptoms and ingestion of a meal in functional dyspepsia. Gut. 2008;57(11):1495-503. DOI:10.1136/gut.2007.137125
9. McBride D, Hardoon S, Walters K, et al. Explaining variation in referral from primary to secondary care: cohort study. BMJ. 2010;341:c6267. DOI:10.1136/bmj.c6267
10. Lacy BE, Weiser KT, Kennedy AT, et al. Functional dyspepsia: the economic impact to patients. Aliment Pharmacol Ther. 2013;38(2):170-7. DOI:10.1111/apt.12355
11. Harer KN, Hasler WL. Functional Dyspepsia: A Review of the Symptoms, Evaluation, and Treatment Options. Gastroenterol Hepatol (N Y). 2020;16(2):66-74. 
12. Parfenov AI, Akhmadullina OV, Belostotsky NI, et al. Enteropathy with impaired membrane digestion and the prospects for cytoprotective therapy. Terapevticheskii Arkhiv (Ter. Arkh.). 2021;93(2):129-37 (in Russian). DOI:10.26442/00403660.2021.02.200602
13. Aro P, Talley NJ, Agréus L, et al. Functional dyspepsia impairs quality of life in the adult population. Aliment Pharmacol Ther. 2011;33(11):1215-24.
DOI:10.1111/j.1365-2036.2011.04640.x
14. Wang C, Fang X. Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia. J Neurogastroenterol Motil. 2021;27(2):153-64. DOI:10.5056/jnm20175
15. Talley NJ, Ford AC. Functional Dyspepsia. N Engl J Med. 2015;373(19):1853-63. DOI:10.1056/NEJMra1501505
16. Walker MM, Aggarwal KR, Shim LS, et al. Duodenal eosinophilia and early satiety in functional dyspepsia: confirmation of a positive association in an Australian cohort. J Gastroenterol Hepatol. 2014;29(3):474-9. DOI:10.1111/jgh.12419
17. Wauters L, Dickman R, Drug V, et al. United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia. United European Gastroenterol J. 2021;9(3):307-31. DOI:10.1002/ueg2.12061
18. National Institute for Health and Care Excellence. Dyspepsia and Gastro‑oesophageal Reflux Disease in Adults. Quality Standard QS96. London: NICE, 2015.
19. Futagami S, Itoh T, Sakamoto C. Systematic review with meta-analysis: post-infectious functional dyspepsia. Aliment Pharmacol Ther. 2015;41(2):177-88. DOI:10.1111/apt.13006
20. Meeroff JC, Schreiber DS, Trier JS, Blacklow NR. Abnormal gastric motor function in viral gastroenteritis. Ann Intern Med. 1980;92(3):370-3. 
DOI:10.7326/0003-4819-92-3-370
21. Stanzel RDP, Lourenssen S, Blennerhassett MG. Inflammation causes expression of NGF in epithelial cells of the rat colon. Exp Neurol. 2008;211(1):203-13. DOI:10.1016/j.expneurol.2008.01.028
22. Demir IE, Schäfer KH, Tieftrunk E, et al. Neural plasticity in the gastrointestinal tract: chronic inflammation, neurotrophic signals, and hypersensitivity. Acta Neuropathol. 2013;125(4):491-509. DOI:10.1007/s00401-013-1099-4
23. Depoortere I. Taste receptors of the gut: emerging roles in health and disease. Gut. 2014;63(1):179-90. DOI:10.1136/gutjnl-2013-305112
24. Van den Houte K, Scarpellini E, Verbeure W, et al. The Role of GI Peptides in Functional Dyspepsia and Gastroparesis: A Systematic Review. Front Psychiatry. 2020;11:172. DOI:10.3389/fpsyt.2020.00172
25. Miwa H. Why dyspepsia can occur without organic disease: pathogenesis and management of functional dyspepsia. J Gastroenterol. 2012;47(8):862-71.
DOI:10.1007/s00535-012-0625-9
26. Camilleri M, Dubois D, Coulie B, et al. Prevalence and socioeconomic impact of upper gastrointestinal disorders in the United States: results of the US Upper Gastrointestinal Study. Clin Gastroenterol Hepatol. 2005;3(6):543-52.
DOI:10.1016/s1542-3565(05)00153-9
27. Vakil N, Talley N, van Zanten SV, et al. Cost of detecting malignant lesions by endoscopy in 2741 primary care dyspeptic patients without alarm symptoms. Clin Gastroenterol Hepatol. 2009;7(7):756-61. DOI:10.1016/j.cgh.2009.03.031
28. Oh JH, Kwon JG, Jung HK, et al. Clinical Practice Guidelines for Functional Dyspepsia in Korea. J Neurogastroenterol Motil. 2020;26(1):29-50. 
DOI:10.5056/jnm19209
29. Lee MJ, Jung HK, Lee KE, et al. Degranulated Eosinophils Contain More Fine Nerve Fibers in the Duodenal Mucosa of Patients With Functional Dyspepsia. J Neurogastroenterol Motil. 2019;25(2):212-21. DOI:10.5056/jnm18176
30. Moayyedi P, Mason J. Clinical and economic consequences of dyspepsia in the community. Gut. 2002;50(Suppl. 4):iv10-2. DOI:10.1136/gut.50.suppl_4.iv1
31. Camilleri M, Parkman HP, Shafi MA, et al.; American College of Gastroenterology. Clinical guideline: management of gastroparesis. Am J Gastroenterol. 2013;108(1):18-37; quiz 38. DOI:10.1038/ajg.2012.373
32. Sarnelli G, Caenepeel P, Geypens B, et al. Symptoms associated with impaired gastric emptying of solids and liquids in functional dyspepsia. Am J Gastroenterol. 2003;98(4):783-8. DOI:10.1111/j.1572-0241.2003.07389.x
33. Ford AC, Bercik P, Morgan DG, et al. The Rome III criteria for the diagnosis of functional dyspepsia in secondary care are not superior to previous definitions. Gastroenterology. 2014;146(4):932-40; quiz e14-5. 
DOI:10.1053/j.gastro.2014.01.014
34. Wang YP, Herndon CC, Lu CL. Non-pharmacological Approach in the Management of Functional Dyspepsia. J Neurogastroenterol Motil. 2020;26(1):6-15. DOI:10.5056/jnm19005
35. Pinto-Sanchez MI, Yuan Y, Hassan A, et al. Proton pump inhibitors for functional dyspepsia. Cochrane Database Syst Rev. 2017;11:CD011194. DOI:10.1002/14651858.CD011194.pub
36. Yamawaki H, Futagami S, Wakabayashi M, et al. Management of functional dyspepsia: state of the art and emerging therapies. Ther Adv Chronic Dis. 2018;9(1):23-32. DOI:10.1177/2040622317725479
37. Sonnenberg A, Lash RH, Genta RM. A national study of Helicobactor pylori infection in gastric biopsy specimens. Gastroenterology. 2010;139(6):1894-901.e2; quiz e12. DOI:10.1053/j.gastro.2010.08.018
38. Sugano K, Tack J, Kuipers EJ, et al. Kyoto global consensus report on Helicobacter pylori gastritis. Gut. 2015;64(9):1353-67. DOI:10.1136/gutjnl-2015-309252
39. Tack J, Janssen P, Masaoka T, et al. Efficacy of buspirone, a fundus-relaxing drug, in patients with functional dyspepsia. Clin Gastroenterol Hepatol. 2012;10(11):1239-45. DOI:10.1016/j.cgh.2012.06.036
40. Vakil N, Halling K, Ohlsson L, Wernersson B. Symptom overlap between postprandial distress and epigastric pain syndromes of the Rome III dyspepsia classification. Am J Gastroenterol. 2013;108(5):767-74. DOI:10.1038/ajg.2013.89
41. Ford AC, Luthra P, Tack J, et al. Efficacy of psychotropic drugs in functional dyspepsia: systematic review and meta-analysis. Gut. 2017;66(3):411-20.
DOI:10.1136/gutjnl-2015-310721
42. National Institute for Health and Care Excellence. Gastro-Oesophageal Reflux Disease and Dyspepsia in Adults: Investigation and Management. Clinical Guideline CG184. London: NICE, 2014.
43. Ivashkin VT, Mayev IV, Sheptulin AA, et al. Diagnosis and treatment of the functional dyspepsia: clinical guidelines of the Russian Gastroenterological Association. Rossijskij zhurnal gastroenterologii, gepatologii, koloproktologii. 2017;27(1):50-61 (in Russian).
DOI:10.22416/1382-4376-2017-27-1-50-61
44. Drossman DA. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV. Gastroenterology. 2016:S0016-5085(16)00223-7. DOI:10.1053/j.gastro.2016.02.032
45. Bang CS, Kim JH, Baik GH, et al. Mosapride treatment for functional dyspepsia: a meta-analysis. J Gastroenterol Hepatol. 2015;30(1):28-42. 
DOI:10.1111/jgh.12662
46. Quigley EMM. Cisapride: what can we learn from the rise and fall of a prokinetic? J Dig Dis. 2011;12(3):147-56. DOI:10.1111/j.1751-2980.2011.00491.x
47. Doggrell SA, Hancox JC. Cardiac safety concerns for domperidone, an antiemetic and prokinetic, and galactogogue medicine. Expert Opin Drug Saf. 2014;13(1):131-8. DOI:10.1517/14740338.2014.851193
48. Yang YJ, Bang CS, Baik GH, et al. Prokinetics for the treatment of functional dyspepsia: Bayesian network meta-analysis. BMC Gastroenterol. 2017;17(1):83.
DOI:10.1186/s12876-017-0639-0
49. Al Quraan AM, Beriwal N, Sangay P, Namgyal T. The Psychotic Impact of Helicobacter pylori Gastritis and Functional Dyspepsia on Depression: A Systematic Review. Cureus. 2019;11(10):e5956. DOI:10.7759/cureus.5956
50. Kareva EN, Serebrova SYu. Challenges in drug treatment of gastric motility disorders. Eksperimental'naya i klinicheskaya gastroenterologiya. 2017;143(7):167-83 (in Russian).

М.А. Осадчук*1, А.А. Свистунов1, Д.В. Балашов1,2, М.М. Осадчук2

1 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет), Москва, Россия;
2 ГБУЗ «Городская поликлиника №52» Департамента здравоохранения г. Москвы, Москва, Россия
*osadchuk.mikhail@yandex.ru

________________________________________________

Mikhail A. Osadchuk*1, Andrei A. Svistunov1, Dmitrii V. Balashov1,2, Maksim M. Osadchuk2

1 Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia;
2 Moscow City Polyclinic №52, Moscow, Russia
*osadchuk.mikhail@yandex.ru