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Тактика антикоагулянтной терапии у пациентов с сердечными имплантируемыми электронными устройствами и субклинической фибрилляцией предсердий
Тактика антикоагулянтной терапии у пациентов с сердечными имплантируемыми электронными устройствами и субклинической фибрилляцией предсердий
Разина Т.В., Серова М.В., Андреев Д.А., Сазонова Ю.С., Комарова А.Г. Тактика антикоагулянтной терапии у пациентов с сердечными имплантируемыми электронными устройствами и субклинической фибрилляцией предсердий. Терапевтический архив. 2023;95(4):347–353.
DOI: 10.26442/00403660.2023.04.202189
© ООО «КОНСИЛИУМ МЕДИКУМ», 2023 г.
DOI: 10.26442/00403660.2023.04.202189
© ООО «КОНСИЛИУМ МЕДИКУМ», 2023 г.
________________________________________________
Материалы доступны только для специалистов сферы здравоохранения. Авторизуйтесь или зарегистрируйтесь.
Аннотация
В настоящее время большое внимание уделяется скринингу для выявления фибрилляции предсердий (ФП). Существенный интерес представляют больные с сердечными имплантируемыми электронными устройствами, позволяющими регистрировать эпизоды предсердных аритмий различной продолжительности, в том числе бессимптомные, которые получили название субклинической ФП (СКФП). Имеющиеся данные свидетельствуют о том, что риск тромбоэмболических осложнений у пациентов с СКФП и клинически явной ФП неодинаковый. До конца не решенными остаются вопросы по тактике антикоагулянтной терапии у пациентов с СКФП. В статье представлен обзор проведенных и текущих исследований, посвященных данной проблеме, а также современные рекомендации по назначению антикоагулянтов пациентам с СКФП и сердечными имплантируемыми электронными устройствами.
Ключевые слова: антикоагулянтная терапия, субклиническая фибрилляция предсердий, эпизоды частого предсердного ритма, сердечные имплантируемые электронные устройства
Keywords: anticoagulant therapy, subclinical atrial fibrillation, atrial high-rate episodes, cardiac implantable electronic devices
Ключевые слова: антикоагулянтная терапия, субклиническая фибрилляция предсердий, эпизоды частого предсердного ритма, сердечные имплантируемые электронные устройства
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Keywords: anticoagulant therapy, subclinical atrial fibrillation, atrial high-rate episodes, cardiac implantable electronic devices
Полный текст
Список литературы
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16. Healey JS, Connolly SJ, Gold MR, et al. Subclinical atrial fibrillation and the risk of stroke. New Engl J Med. 2012;366(2):120-9. DOI:10.1056/nejmoa1105575
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18. Hohnloser HS, Capucci A, Fain E, et al. Asymptomatic atrial fibrillation and stroke evaluation in pacemaker patients and the atrial fibrillation reduction atrial pacing trial (assert). Am Heart J. 2006;152(3):442-7. DOI:10.1016/j.ahj.2006.02.016
19. Diederichsen SZ, Haugan KJ, Brandes A, et al. Natural History of Subclinical Atrial Fibrillation Detected by Implanted Loop Recorders. J Am Coll Cardiol. 2019;74(22):2771-81. DOI:10.1016/j.jacc.2019.09.050
20. Lip GYH, Nieuwlaat R, Pisters R, et al. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach. Chest. 2010;137(2):263-72. DOI:10.1378/chest.09-1584
21. Glotzer TV, Hellkamp AS, Zimmerman J, et al. Atrial high rate episodes detected by pacemaker diagnostics predict death and stroke: report of the Atrial Diagnostics Ancillary Study of the MOde Selection Trial (MOST). Circulation. 2003;107(12):1614-9. DOI:10.1161/01.CIR.0000057981.70380.45
22. Capucci A, Santini M, Padeletti L, et al. Monitored atrial fibrillation duration predicts arterial embolic events in patients suffering from bradycardia and atrial fibrillation implanted with antitachycardia pacemakers. J Am Coll Cardiol. 2005;46(10):1913-20. DOI:10.1016/j.jacc.2005.07.044
23. Glotzer TV, Daoud EG, Wyse DG, et al. The relationship between daily atrial tachyarrhythmia burden from implantable device diagnostics and stroke risk. Circ Arrhythm Electrophysiol. 2009;2(5):474-80. DOI:10.1161/circep.109.849638
24. Shanmugam N, Boerdlein A, Proff J, et al. Detection of atrial high-rate events by continuous home monitoring: Clinical significance in the heart failure-cardiac resynchronization therapy population. Europace. 2011;14(2):230-7. DOI:10.1093/europace/eur293
25. Healey JS, Connolly SJ, Gold MR, et al. Subclinical atrial fibrillation and the risk of stroke. New England J Med. 2012;366(2):120-9. DOI:10.1056/nejmoa1105575
26. Van Gelder IC, Healey JS, Crijns HJGM, et al. Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in assert. Eur Heart J. 2017;38(17):1339-44. DOI:10.1093/eurheartj/ehx042
27. Boriani G, Glotzer TV, Santini M, et al. Device-detected atrial fibrillation and risk for stroke: an analysis of >10,000 patients from the SOS AF project (Stroke preventiOn Strategies based on Atrial Fibrillation information from implanted devices). Eur Heart J. 2014;35(8):508-16. DOI:10.1093/eurheartj/eht491
28. Botto GL, Padeletti L, Santini M, et al. Presence and duration of atrial fibrillation detected by continuous monitoring: crucial implications for the risk of thromboembolic events. J Cardiovasc Electrophysiol. 2009;20(3):241-8. DOI:10.1111/j.1540-8167.2008.01320.x
29. Nasir JM, Pomeroy W, Marler A, et al. Predicting Determinants of Atrial Fibrillation or Flutter for Therapy Elucidation in Patients at Risk for Thromboembolic Events (PREDATE AF) Study. Heart Rhythm. 2017;14(7):955-61. DOI:10.1016/j.hrthm.2017.04.026
30. Reiffel JA, Verma A, Kowey PR, et al. Incidence of previously undiagnosed atrial fibrillation using insertable cardiac monitors in a high-risk population. JAMA Cardiol. 2017;2(10):1120. DOI:10.1001/jamacardio.2017.3180
31. Perino AC, Fan J, Askari M, et al. Practice variation in anticoagulation prescription and outcomes after device-detected atrial fibrillation. Circulation. 2019;139(22):2502-12. DOI:10.1161/circulationaha.118.038988
32. Boriani G, Glotzer TV, Ziegler PD, et al. Detection of new atrial fibrillation in patients with cardiac implanted electronic devices and factors associated with transition to higher device-detected atrial fibrillation burden. Heart Rhythm. 2018;15(3):376-83. DOI:10.1016/j.hrthm.2017.11.007
33. Celikyurt U, Knecht S, Kuehne M, et al. Incidence of new-onset atrial fibrillation after cavotricuspid isthmus ablation for atrial flutter. Europace. 2017;19(11):1776-80. DOI:10.1093/europace/euw343
34. Kirchhof P, Blank BF, Calvert M, et al. Probing oral anticoagulation in patients with atrial high rate episodes: Rationale and design of the non-vitamin K antagonist oral anticoagulants in patients with atrial high rate episodes (Noah–AFNET 6) trial. Am Heart J. 2017;190:12-8. DOI:10.1016/j.ahj.2017.04.015
35. Lopes RD, Alings M, Connolly SJ, et al. Rationale and design of the apixaban for the reduction of thrombo-embolism in patients with device-detected sub-clinical atrial fibrillation (ARTESiA) trial. Am Heart J. 2017;189:137-45. DOI:10.1016/j.ahj.2017.04.008
2. Stewart S, Hart CL, Hole DJ, McMurray JJ. A population-based study of the long-term risks associated with atrial fibrillation: 20-year follow-up of the Renfrew/Paisley study. Am J Med. 2002;113(5):359-64. DOI:10.1016/s0002-9343(02)01236-6
3. Chugh SS, Blackshear JL, Shen WK, et al. Epidemiology and natural history of atrial fibrillation: Clinical implications. J Am Coll Cardiol. 2001;37(2):371-8.
DOI:10.1016/s0735-1097(00)01107-4
4. Akao M, Chun YH, Wada H, et al. Current status of clinical background of patients with atrial fibrillation in a community-based survey: The Fushimi AF Registry. J Cardiol. 2013;61(4):260-6. DOI:10.1016/j.jjcc.2012.12.002
5. Nieuwlaat R, Capucci A, Camm AJ, et al. Atrial Fibrillation Management: A prospective survey in ESC member countries. Eur Heart J. 2005;26(22):2422-34. DOI:10.1093/eurheartj/ehi505
6. Rienstra M, Vermond RA, Crijns HJGM, et al. Asymptomatic persistent atrial fibrillation and outcome: Results of the race study. Heart Rhythm. 2014;11(6):939-45. DOI:10.1016/j.hrthm.2014.03.016
7. Andersson T, Magnuson A, Bryngelsson IL, et al. All-cause mortality in 272 186 patients hospitalized with incident atrial fibrillation 1995–2008: A Swedish nationwide long-term case-control study. Eur Heart J. 2013;34(14):1061-7. DOI:10.1093/eurheartj/ehs469
8. Boriani G, Laroche C, Diemberger I, et al. Asymptomatic atrial fibrillation: Clinical correlates, management, and outcomes in the EORP-AF Pilot general registry. Am J Med. 2015;128(5). DOI:10.1016/j.amjmed.2014.11.026
9. Rienstra M, Lubitz SA, Mahida S, et al. Symptoms and functional status of patients with atrial fibrillation. Circulation. 2012;125(23):2933-43. DOI:10.1161/circulationaha.111.069450
10. Байрамова С.А., Романов А.Б., Mittal S., и др. Имплантируемый аппарат длительного мониторирования ЭКГ для выявления фибрилляции предсердий после аблации кавотрикуспидального перешейка у пациентов с трепетанием предсердий. Патология кровообращения и кардиохирургия. 2015;19(3):100-9 [Bajramova SA, Romanov AB, Mittal S, et al. Long-term ECG monitoring using an implantable loop recorder for the detection of atrial fibrillation after cavotricuspid isthmus ablation in patients with atrial flutter. Patologija krovoobrashhenija i kardiohirurgija. 2015;19(3):100-9 (in Russian)].
11. Мамчур С.Е., Иваницкий Э.А., Поликутина О.М., и др. Эффективность выявления мерцательной аритмии при криптогенном инсульте по данным имплантируемых мониторов электрокардиограммы: пилотное исследование. Сибирский медицинский журнал. 2019;34(2):47-53 [Mamchur SE, Ivanitskiy EA, Polikutina OM, et al. Efficacy of atrial fibrillation detection in cryptogenic stroke according to data of implantable loop recorders: pilot study. The Siberian Journal of Clinical and Experimental Medicine. 2019;34(2):47-53 (in Russian)]. DOI:10.29001/2073-8552-2019-34-2-47-53
12. Hindricks G, Potpara T, Dagres N, et al. 2020 ESC guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (eacts). Eur Heart J. 2020;42(5):373-498. DOI:10.1093/eurheartj/ehaa612
13. Swiryn S, Orlov MV, Benditt DG, et al. Clinical implications of brief device-detected atrial tachyarrhythmias in a cardiac rhythm management device population. Circulation. 2016;134(16):1130-40. DOI:10.1161/circulationaha.115.020252
14. Mahajan R, Perera T, Elliott AD, et al. Subclinical device-detected atrial fibrillation and stroke risk: A systematic review and meta-analysis. Eur Heart J. 2018;39(16):1407-15. DOI:10.1093/eurheartj/ehx731
15. Boriani G, Glotzer TV, Ziegler PD, et al. Detection of new atrial fibrillation in patients with cardiac implanted electronic devices and factors associated with transition to higher device-detected atrial fibrillation burden. Heart Rhythm. 2018;15(3):376-83. DOI:10.1016/j.hrthm.2017.11.007
16. Healey JS, Connolly SJ, Gold MR, et al. Subclinical atrial fibrillation and the risk of stroke. New Engl J Med. 2012;366(2):120-9. DOI:10.1056/nejmoa1105575
17. Gonzalez M, Keating RJ, Markowitz SM, et al. Newly detected atrial high rate episodes predict long-term mortality outcomes in patients with permanent pacemakers. Heart Rhythm. 2014;11(12):2214-21. DOI:10.1016/j.hrthm.2014.08.019
18. Hohnloser HS, Capucci A, Fain E, et al. Asymptomatic atrial fibrillation and stroke evaluation in pacemaker patients and the atrial fibrillation reduction atrial pacing trial (assert). Am Heart J. 2006;152(3):442-7. DOI:10.1016/j.ahj.2006.02.016
19. Diederichsen SZ, Haugan KJ, Brandes A, et al. Natural History of Subclinical Atrial Fibrillation Detected by Implanted Loop Recorders. J Am Coll Cardiol. 2019;74(22):2771-81. DOI:10.1016/j.jacc.2019.09.050
20. Lip GYH, Nieuwlaat R, Pisters R, et al. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach. Chest. 2010;137(2):263-72. DOI:10.1378/chest.09-1584
21. Glotzer TV, Hellkamp AS, Zimmerman J, et al. Atrial high rate episodes detected by pacemaker diagnostics predict death and stroke: report of the Atrial Diagnostics Ancillary Study of the MOde Selection Trial (MOST). Circulation. 2003;107(12):1614-9. DOI:10.1161/01.CIR.0000057981.70380.45
22. Capucci A, Santini M, Padeletti L, et al. Monitored atrial fibrillation duration predicts arterial embolic events in patients suffering from bradycardia and atrial fibrillation implanted with antitachycardia pacemakers. J Am Coll Cardiol. 2005;46(10):1913-20. DOI:10.1016/j.jacc.2005.07.044
23. Glotzer TV, Daoud EG, Wyse DG, et al. The relationship between daily atrial tachyarrhythmia burden from implantable device diagnostics and stroke risk. Circ Arrhythm Electrophysiol. 2009;2(5):474-80. DOI:10.1161/circep.109.849638
24. Shanmugam N, Boerdlein A, Proff J, et al. Detection of atrial high-rate events by continuous home monitoring: Clinical significance in the heart failure-cardiac resynchronization therapy population. Europace. 2011;14(2):230-7. DOI:10.1093/europace/eur293
25. Healey JS, Connolly SJ, Gold MR, et al. Subclinical atrial fibrillation and the risk of stroke. New England J Med. 2012;366(2):120-9. DOI:10.1056/nejmoa1105575
26. Van Gelder IC, Healey JS, Crijns HJGM, et al. Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in assert. Eur Heart J. 2017;38(17):1339-44. DOI:10.1093/eurheartj/ehx042
27. Boriani G, Glotzer TV, Santini M, et al. Device-detected atrial fibrillation and risk for stroke: an analysis of >10,000 patients from the SOS AF project (Stroke preventiOn Strategies based on Atrial Fibrillation information from implanted devices). Eur Heart J. 2014;35(8):508-16. DOI:10.1093/eurheartj/eht491
28. Botto GL, Padeletti L, Santini M, et al. Presence and duration of atrial fibrillation detected by continuous monitoring: crucial implications for the risk of thromboembolic events. J Cardiovasc Electrophysiol. 2009;20(3):241-8. DOI:10.1111/j.1540-8167.2008.01320.x
29. Nasir JM, Pomeroy W, Marler A, et al. Predicting Determinants of Atrial Fibrillation or Flutter for Therapy Elucidation in Patients at Risk for Thromboembolic Events (PREDATE AF) Study. Heart Rhythm. 2017;14(7):955-61. DOI:10.1016/j.hrthm.2017.04.026
30. Reiffel JA, Verma A, Kowey PR, et al. Incidence of previously undiagnosed atrial fibrillation using insertable cardiac monitors in a high-risk population. JAMA Cardiol. 2017;2(10):1120. DOI:10.1001/jamacardio.2017.3180
31. Perino AC, Fan J, Askari M, et al. Practice variation in anticoagulation prescription and outcomes after device-detected atrial fibrillation. Circulation. 2019;139(22):2502-12. DOI:10.1161/circulationaha.118.038988
32. Boriani G, Glotzer TV, Ziegler PD, et al. Detection of new atrial fibrillation in patients with cardiac implanted electronic devices and factors associated with transition to higher device-detected atrial fibrillation burden. Heart Rhythm. 2018;15(3):376-83. DOI:10.1016/j.hrthm.2017.11.007
33. Celikyurt U, Knecht S, Kuehne M, et al. Incidence of new-onset atrial fibrillation after cavotricuspid isthmus ablation for atrial flutter. Europace. 2017;19(11):1776-80. DOI:10.1093/europace/euw343
34. Kirchhof P, Blank BF, Calvert M, et al. Probing oral anticoagulation in patients with atrial high rate episodes: Rationale and design of the non-vitamin K antagonist oral anticoagulants in patients with atrial high rate episodes (Noah–AFNET 6) trial. Am Heart J. 2017;190:12-8. DOI:10.1016/j.ahj.2017.04.015
35. Lopes RD, Alings M, Connolly SJ, et al. Rationale and design of the apixaban for the reduction of thrombo-embolism in patients with device-detected sub-clinical atrial fibrillation (ARTESiA) trial. Am Heart J. 2017;189:137-45. DOI:10.1016/j.ahj.2017.04.008
2. Stewart S, Hart CL, Hole DJ, McMurray JJ. A population-based study of the long-term risks associated with atrial fibrillation: 20-year follow-up of the Renfrew/Paisley study. Am J Med. 2002;113(5):359-64. DOI:10.1016/s0002-9343(02)01236-6
3. Chugh SS, Blackshear JL, Shen WK, et al. Epidemiology and natural history of atrial fibrillation: Clinical implications. J Am Coll Cardiol. 2001;37(2):371-8.
DOI:10.1016/s0735-1097(00)01107-4
4. Akao M, Chun YH, Wada H, et al. Current status of clinical background of patients with atrial fibrillation in a community-based survey: The Fushimi AF Registry. J Cardiol. 2013;61(4):260-6. DOI:10.1016/j.jjcc.2012.12.002
5. Nieuwlaat R, Capucci A, Camm AJ, et al. Atrial Fibrillation Management: A prospective survey in ESC member countries. Eur Heart J. 2005;26(22):2422-34. DOI:10.1093/eurheartj/ehi505
6. Rienstra M, Vermond RA, Crijns HJGM, et al. Asymptomatic persistent atrial fibrillation and outcome: Results of the race study. Heart Rhythm. 2014;11(6):939-45. DOI:10.1016/j.hrthm.2014.03.016
7. Andersson T, Magnuson A, Bryngelsson IL, et al. All-cause mortality in 272 186 patients hospitalized with incident atrial fibrillation 1995–2008: A Swedish nationwide long-term case-control study. Eur Heart J. 2013;34(14):1061-7. DOI:10.1093/eurheartj/ehs469
8. Boriani G, Laroche C, Diemberger I, et al. Asymptomatic atrial fibrillation: Clinical correlates, management, and outcomes in the EORP-AF Pilot general registry. Am J Med. 2015;128(5). DOI:10.1016/j.amjmed.2014.11.026
9. Rienstra M, Lubitz SA, Mahida S, et al. Symptoms and functional status of patients with atrial fibrillation. Circulation. 2012;125(23):2933-43. DOI:10.1161/circulationaha.111.069450
10. Байрамова С.А., Романов А.Б., Mittal S., и др. Имплантируемый аппарат длительного мониторирования ЭКГ для выявления фибрилляции предсердий после аблации кавотрикуспидального перешейка у пациентов с трепетанием предсердий. Патология кровообращения и кардиохирургия. 2015;19(3):100-9 [Bajramova SA, Romanov AB, Mittal S, et al. Long-term ECG monitoring using an implantable loop recorder for the detection of atrial fibrillation after cavotricuspid isthmus ablation in patients with atrial flutter. Patologija krovoobrashhenija i kardiohirurgija. 2015;19(3):100-9 (in Russian)].
11. Мамчур С.Е., Иваницкий Э.А., Поликутина О.М., и др. Эффективность выявления мерцательной аритмии при криптогенном инсульте по данным имплантируемых мониторов электрокардиограммы: пилотное исследование. Сибирский медицинский журнал. 2019;34(2):47-53 [Mamchur SE, Ivanitskiy EA, Polikutina OM, et al. Efficacy of atrial fibrillation detection in cryptogenic stroke according to data of implantable loop recorders: pilot study. The Siberian Journal of Clinical and Experimental Medicine. 2019;34(2):47-53 (in Russian)]. DOI:10.29001/2073-8552-2019-34-2-47-53
12. Hindricks G, Potpara T, Dagres N, et al. 2020 ESC guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (eacts). Eur Heart J. 2020;42(5):373-498. DOI:10.1093/eurheartj/ehaa612
13. Swiryn S, Orlov MV, Benditt DG, et al. Clinical implications of brief device-detected atrial tachyarrhythmias in a cardiac rhythm management device population. Circulation. 2016;134(16):1130-40. DOI:10.1161/circulationaha.115.020252
14. Mahajan R, Perera T, Elliott AD, et al. Subclinical device-detected atrial fibrillation and stroke risk: A systematic review and meta-analysis. Eur Heart J. 2018;39(16):1407-15. DOI:10.1093/eurheartj/ehx731
15. Boriani G, Glotzer TV, Ziegler PD, et al. Detection of new atrial fibrillation in patients with cardiac implanted electronic devices and factors associated with transition to higher device-detected atrial fibrillation burden. Heart Rhythm. 2018;15(3):376-83. DOI:10.1016/j.hrthm.2017.11.007
16. Healey JS, Connolly SJ, Gold MR, et al. Subclinical atrial fibrillation and the risk of stroke. New Engl J Med. 2012;366(2):120-9. DOI:10.1056/nejmoa1105575
17. Gonzalez M, Keating RJ, Markowitz SM, et al. Newly detected atrial high rate episodes predict long-term mortality outcomes in patients with permanent pacemakers. Heart Rhythm. 2014;11(12):2214-21. DOI:10.1016/j.hrthm.2014.08.019
18. Hohnloser HS, Capucci A, Fain E, et al. Asymptomatic atrial fibrillation and stroke evaluation in pacemaker patients and the atrial fibrillation reduction atrial pacing trial (assert). Am Heart J. 2006;152(3):442-7. DOI:10.1016/j.ahj.2006.02.016
19. Diederichsen SZ, Haugan KJ, Brandes A, et al. Natural History of Subclinical Atrial Fibrillation Detected by Implanted Loop Recorders. J Am Coll Cardiol. 2019;74(22):2771-81. DOI:10.1016/j.jacc.2019.09.050
20. Lip GYH, Nieuwlaat R, Pisters R, et al. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach. Chest. 2010;137(2):263-72. DOI:10.1378/chest.09-1584
21. Glotzer TV, Hellkamp AS, Zimmerman J, et al. Atrial high rate episodes detected by pacemaker diagnostics predict death and stroke: report of the Atrial Diagnostics Ancillary Study of the MOde Selection Trial (MOST). Circulation. 2003;107(12):1614-9. DOI:10.1161/01.CIR.0000057981.70380.45
22. Capucci A, Santini M, Padeletti L, et al. Monitored atrial fibrillation duration predicts arterial embolic events in patients suffering from bradycardia and atrial fibrillation implanted with antitachycardia pacemakers. J Am Coll Cardiol. 2005;46(10):1913-20. DOI:10.1016/j.jacc.2005.07.044
23. Glotzer TV, Daoud EG, Wyse DG, et al. The relationship between daily atrial tachyarrhythmia burden from implantable device diagnostics and stroke risk. Circ Arrhythm Electrophysiol. 2009;2(5):474-80. DOI:10.1161/circep.109.849638
24. Shanmugam N, Boerdlein A, Proff J, et al. Detection of atrial high-rate events by continuous home monitoring: Clinical significance in the heart failure-cardiac resynchronization therapy population. Europace. 2011;14(2):230-7. DOI:10.1093/europace/eur293
25. Healey JS, Connolly SJ, Gold MR, et al. Subclinical atrial fibrillation and the risk of stroke. New England J Med. 2012;366(2):120-9. DOI:10.1056/nejmoa1105575
26. Van Gelder IC, Healey JS, Crijns HJGM, et al. Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in assert. Eur Heart J. 2017;38(17):1339-44. DOI:10.1093/eurheartj/ehx042
27. Boriani G, Glotzer TV, Santini M, et al. Device-detected atrial fibrillation and risk for stroke: an analysis of >10,000 patients from the SOS AF project (Stroke preventiOn Strategies based on Atrial Fibrillation information from implanted devices). Eur Heart J. 2014;35(8):508-16. DOI:10.1093/eurheartj/eht491
28. Botto GL, Padeletti L, Santini M, et al. Presence and duration of atrial fibrillation detected by continuous monitoring: crucial implications for the risk of thromboembolic events. J Cardiovasc Electrophysiol. 2009;20(3):241-8. DOI:10.1111/j.1540-8167.2008.01320.x
29. Nasir JM, Pomeroy W, Marler A, et al. Predicting Determinants of Atrial Fibrillation or Flutter for Therapy Elucidation in Patients at Risk for Thromboembolic Events (PREDATE AF) Study. Heart Rhythm. 2017;14(7):955-61. DOI:10.1016/j.hrthm.2017.04.026
30. Reiffel JA, Verma A, Kowey PR, et al. Incidence of previously undiagnosed atrial fibrillation using insertable cardiac monitors in a high-risk population. JAMA Cardiol. 2017;2(10):1120. DOI:10.1001/jamacardio.2017.3180
31. Perino AC, Fan J, Askari M, et al. Practice variation in anticoagulation prescription and outcomes after device-detected atrial fibrillation. Circulation. 2019;139(22):2502-12. DOI:10.1161/circulationaha.118.038988
32. Boriani G, Glotzer TV, Ziegler PD, et al. Detection of new atrial fibrillation in patients with cardiac implanted electronic devices and factors associated with transition to higher device-detected atrial fibrillation burden. Heart Rhythm. 2018;15(3):376-83. DOI:10.1016/j.hrthm.2017.11.007
33. Celikyurt U, Knecht S, Kuehne M, et al. Incidence of new-onset atrial fibrillation after cavotricuspid isthmus ablation for atrial flutter. Europace. 2017;19(11):1776-80. DOI:10.1093/europace/euw343
34. Kirchhof P, Blank BF, Calvert M, et al. Probing oral anticoagulation in patients with atrial high rate episodes: Rationale and design of the non-vitamin K antagonist oral anticoagulants in patients with atrial high rate episodes (Noah–AFNET 6) trial. Am Heart J. 2017;190:12-8. DOI:10.1016/j.ahj.2017.04.015
35. Lopes RD, Alings M, Connolly SJ, et al. Rationale and design of the apixaban for the reduction of thrombo-embolism in patients with device-detected sub-clinical atrial fibrillation (ARTESiA) trial. Am Heart J. 2017;189:137-45. DOI:10.1016/j.ahj.2017.04.008
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2. Stewart S, Hart CL, Hole DJ, McMurray JJ. A population-based study of the long-term risks associated with atrial fibrillation: 20-year follow-up of the Renfrew/Paisley study. Am J Med. 2002;113(5):359-64. DOI:10.1016/s0002-9343(02)01236-6
3. Chugh SS, Blackshear JL, Shen WK, et al. Epidemiology and natural history of atrial fibrillation: Clinical implications. J Am Coll Cardiol. 2001;37(2):371-8.
DOI:10.1016/s0735-1097(00)01107-4
4. Akao M, Chun YH, Wada H, et al. Current status of clinical background of patients with atrial fibrillation in a community-based survey: The Fushimi AF Registry. J Cardiol. 2013;61(4):260-6. DOI:10.1016/j.jjcc.2012.12.002
5. Nieuwlaat R, Capucci A, Camm AJ, et al. Atrial Fibrillation Management: A prospective survey in ESC member countries. Eur Heart J. 2005;26(22):2422-34. DOI:10.1093/eurheartj/ehi505
6. Rienstra M, Vermond RA, Crijns HJGM, et al. Asymptomatic persistent atrial fibrillation and outcome: Results of the race study. Heart Rhythm. 2014;11(6):939-45. DOI:10.1016/j.hrthm.2014.03.016
7. Andersson T, Magnuson A, Bryngelsson IL, et al. All-cause mortality in 272 186 patients hospitalized with incident atrial fibrillation 1995–2008: A Swedish nationwide long-term case-control study. Eur Heart J. 2013;34(14):1061-7. DOI:10.1093/eurheartj/ehs469
8. Boriani G, Laroche C, Diemberger I, et al. Asymptomatic atrial fibrillation: Clinical correlates, management, and outcomes in the EORP-AF Pilot general registry. Am J Med. 2015;128(5). DOI:10.1016/j.amjmed.2014.11.026
9. Rienstra M, Lubitz SA, Mahida S, et al. Symptoms and functional status of patients with atrial fibrillation. Circulation. 2012;125(23):2933-43. DOI:10.1161/circulationaha.111.069450
10. Байрамова С.А., Романов А.Б., Mittal S., и др. Имплантируемый аппарат длительного мониторирования ЭКГ для выявления фибрилляции предсердий после аблации кавотрикуспидального перешейка у пациентов с трепетанием предсердий. Патология кровообращения и кардиохирургия. 2015;19(3):100-9 [Bajramova SA, Romanov AB, Mittal S, et al. Long-term ECG monitoring using an implantable loop recorder for the detection of atrial fibrillation after cavotricuspid isthmus ablation in patients with atrial flutter. Patologija krovoobrashhenija i kardiohirurgija. 2015;19(3):100-9 (in Russian)].
11. Мамчур С.Е., Иваницкий Э.А., Поликутина О.М., и др. Эффективность выявления мерцательной аритмии при криптогенном инсульте по данным имплантируемых мониторов электрокардиограммы: пилотное исследование. Сибирский медицинский журнал. 2019;34(2):47-53 [Mamchur SE, Ivanitskiy EA, Polikutina OM, et al. Efficacy of atrial fibrillation detection in cryptogenic stroke according to data of implantable loop recorders: pilot study. The Siberian Journal of Clinical and Experimental Medicine. 2019;34(2):47-53 (in Russian)]. DOI:10.29001/2073-8552-2019-34-2-47-53
12. Hindricks G, Potpara T, Dagres N, et al. 2020 ESC guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (eacts). Eur Heart J. 2020;42(5):373-498. DOI:10.1093/eurheartj/ehaa612
13. Swiryn S, Orlov MV, Benditt DG, et al. Clinical implications of brief device-detected atrial tachyarrhythmias in a cardiac rhythm management device population. Circulation. 2016;134(16):1130-40. DOI:10.1161/circulationaha.115.020252
14. Mahajan R, Perera T, Elliott AD, et al. Subclinical device-detected atrial fibrillation and stroke risk: A systematic review and meta-analysis. Eur Heart J. 2018;39(16):1407-15. DOI:10.1093/eurheartj/ehx731
15. Boriani G, Glotzer TV, Ziegler PD, et al. Detection of new atrial fibrillation in patients with cardiac implanted electronic devices and factors associated with transition to higher device-detected atrial fibrillation burden. Heart Rhythm. 2018;15(3):376-83. DOI:10.1016/j.hrthm.2017.11.007
16. Healey JS, Connolly SJ, Gold MR, et al. Subclinical atrial fibrillation and the risk of stroke. New Engl J Med. 2012;366(2):120-9. DOI:10.1056/nejmoa1105575
17. Gonzalez M, Keating RJ, Markowitz SM, et al. Newly detected atrial high rate episodes predict long-term mortality outcomes in patients with permanent pacemakers. Heart Rhythm. 2014;11(12):2214-21. DOI:10.1016/j.hrthm.2014.08.019
18. Hohnloser HS, Capucci A, Fain E, et al. Asymptomatic atrial fibrillation and stroke evaluation in pacemaker patients and the atrial fibrillation reduction atrial pacing trial (assert). Am Heart J. 2006;152(3):442-7. DOI:10.1016/j.ahj.2006.02.016
19. Diederichsen SZ, Haugan KJ, Brandes A, et al. Natural History of Subclinical Atrial Fibrillation Detected by Implanted Loop Recorders. J Am Coll Cardiol. 2019;74(22):2771-81. DOI:10.1016/j.jacc.2019.09.050
20. Lip GYH, Nieuwlaat R, Pisters R, et al. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach. Chest. 2010;137(2):263-72. DOI:10.1378/chest.09-1584
21. Glotzer TV, Hellkamp AS, Zimmerman J, et al. Atrial high rate episodes detected by pacemaker diagnostics predict death and stroke: report of the Atrial Diagnostics Ancillary Study of the MOde Selection Trial (MOST). Circulation. 2003;107(12):1614-9. DOI:10.1161/01.CIR.0000057981.70380.45
22. Capucci A, Santini M, Padeletti L, et al. Monitored atrial fibrillation duration predicts arterial embolic events in patients suffering from bradycardia and atrial fibrillation implanted with antitachycardia pacemakers. J Am Coll Cardiol. 2005;46(10):1913-20. DOI:10.1016/j.jacc.2005.07.044
23. Glotzer TV, Daoud EG, Wyse DG, et al. The relationship between daily atrial tachyarrhythmia burden from implantable device diagnostics and stroke risk. Circ Arrhythm Electrophysiol. 2009;2(5):474-80. DOI:10.1161/circep.109.849638
24. Shanmugam N, Boerdlein A, Proff J, et al. Detection of atrial high-rate events by continuous home monitoring: Clinical significance in the heart failure-cardiac resynchronization therapy population. Europace. 2011;14(2):230-7. DOI:10.1093/europace/eur293
25. Healey JS, Connolly SJ, Gold MR, et al. Subclinical atrial fibrillation and the risk of stroke. New England J Med. 2012;366(2):120-9. DOI:10.1056/nejmoa1105575
26. Van Gelder IC, Healey JS, Crijns HJGM, et al. Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in assert. Eur Heart J. 2017;38(17):1339-44. DOI:10.1093/eurheartj/ehx042
27. Boriani G, Glotzer TV, Santini M, et al. Device-detected atrial fibrillation and risk for stroke: an analysis of >10,000 patients from the SOS AF project (Stroke preventiOn Strategies based on Atrial Fibrillation information from implanted devices). Eur Heart J. 2014;35(8):508-16. DOI:10.1093/eurheartj/eht491
28. Botto GL, Padeletti L, Santini M, et al. Presence and duration of atrial fibrillation detected by continuous monitoring: crucial implications for the risk of thromboembolic events. J Cardiovasc Electrophysiol. 2009;20(3):241-8. DOI:10.1111/j.1540-8167.2008.01320.x
29. Nasir JM, Pomeroy W, Marler A, et al. Predicting Determinants of Atrial Fibrillation or Flutter for Therapy Elucidation in Patients at Risk for Thromboembolic Events (PREDATE AF) Study. Heart Rhythm. 2017;14(7):955-61. DOI:10.1016/j.hrthm.2017.04.026
30. Reiffel JA, Verma A, Kowey PR, et al. Incidence of previously undiagnosed atrial fibrillation using insertable cardiac monitors in a high-risk population. JAMA Cardiol. 2017;2(10):1120. DOI:10.1001/jamacardio.2017.3180
31. Perino AC, Fan J, Askari M, et al. Practice variation in anticoagulation prescription and outcomes after device-detected atrial fibrillation. Circulation. 2019;139(22):2502-12. DOI:10.1161/circulationaha.118.038988
32. Boriani G, Glotzer TV, Ziegler PD, et al. Detection of new atrial fibrillation in patients with cardiac implanted electronic devices and factors associated with transition to higher device-detected atrial fibrillation burden. Heart Rhythm. 2018;15(3):376-83. DOI:10.1016/j.hrthm.2017.11.007
33. Celikyurt U, Knecht S, Kuehne M, et al. Incidence of new-onset atrial fibrillation after cavotricuspid isthmus ablation for atrial flutter. Europace. 2017;19(11):1776-80. DOI:10.1093/europace/euw343
34. Kirchhof P, Blank BF, Calvert M, et al. Probing oral anticoagulation in patients with atrial high rate episodes: Rationale and design of the non-vitamin K antagonist oral anticoagulants in patients with atrial high rate episodes (Noah–AFNET 6) trial. Am Heart J. 2017;190:12-8. DOI:10.1016/j.ahj.2017.04.015
35. Lopes RD, Alings M, Connolly SJ, et al. Rationale and design of the apixaban for the reduction of thrombo-embolism in patients with device-detected sub-clinical atrial fibrillation (ARTESiA) trial. Am Heart J. 2017;189:137-45. DOI:10.1016/j.ahj.2017.04.008
Авторы
Т.В. Разина1, М.В. Серова*1,2, Д.А. Андреев1, Ю.С. Сазонова2, А.Г. Комарова3
1 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет), Москва, Россия;
2 ГБУЗ «Городская клиническая больница №1 им. Н.И. Пирогова» Департамента здравоохранения г. Москвы, Москва, Россия;
3 ГБУЗ «Городская клиническая больница им С.П. Боткина» Департамента здравоохранения г. Москвы, Москва, Россия
*yamarfa@yandex.ru
1 Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia;
2 Pirogov City Clinical Hospital №1, Moscow, Russia;
3 Botkin City Clinical Hospital, Moscow, Russia
*yamarfa@yandex.ru
1 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет), Москва, Россия;
2 ГБУЗ «Городская клиническая больница №1 им. Н.И. Пирогова» Департамента здравоохранения г. Москвы, Москва, Россия;
3 ГБУЗ «Городская клиническая больница им С.П. Боткина» Департамента здравоохранения г. Москвы, Москва, Россия
*yamarfa@yandex.ru
________________________________________________
1 Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia;
2 Pirogov City Clinical Hospital №1, Moscow, Russia;
3 Botkin City Clinical Hospital, Moscow, Russia
*yamarfa@yandex.ru
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