Reznik EV, Iarovoi MD, Zavialova SA, Umakhanova ShM, Grigorievskaya AS, Makolin OI, Semeniakin IV. Combined echinococcosis of the lungs, heart and liver: clinic, diagnosis and treatment. Case report. Terapevticheskii Arkhiv (Ter. Arkh.). 2024;96(11):1097–1103. DOI: 10.26442/00403660.2024.11.202998
Сочетанный эхинококкоз легких, сердца и печени: клиника, диагностика и лечение. Клинический случай
Reznik EV, Iarovoi MD, Zavialova SA, Umakhanova ShM, Grigorievskaya AS, Makolin OI, Semeniakin IV. Combined echinococcosis of the lungs, heart and liver: clinic, diagnosis and treatment. Case report. Terapevticheskii Arkhiv (Ter. Arkh.). 2024;96(11):1097–1103. DOI: 10.26442/00403660.2024.11.202998
Эхинококкоз, или гидатидная болезнь, – паразитарное заболевание, наиболее частым возбудителем которого является Echinococcus granulosus, а также E. multilocularis и E. oligarthrus. Попадая в организм человека, паразит оседает в различных органах, формируя кисты. Чаще всего (75%) они локализуются в печени, где могут сохраняться, не давая никаких клинических проявлений. Также возможна локализация кист в других внутренних органах – легких, сердце. Достаточно редко эхинококковые кисты обнаруживаются сразу в нескольких органах одновременно. Целью представления данного клинического случая является демонстрация пациента, имеющего эхинококковое поражение с локализацией кист в печени, легких и сердце.
Echinococcosis or hidatid disease is a parasitic illness which is caused by the most common pathogens Echinococcus granulosus, E. multilocularis and E. oligarthrus. When the agent gets into the organism, it penetrates the organ and forms a cyst. Cysts are located more often (75%) in the liver where they exist without any clinical manifestation. They can be located in other internal organs: lungs, the heart and others. The localization of cysts in several organs simultaneously is a very rare case. The article aims to demonstrate a patient who had a combined echinococcosis of the lungs, heart and liver.
Keywords: combined echinococcosis, echinococcosis of the lungs, echinococcosis of the heart, echinococcosis of the liver
1. Giuseppe M, Alessandro B, Marco S, et al. An unexpected guest: Pulmonary echinococcosis diagnosed by intraoperative frozen section examination. A case report and literature review. Pathol Res Pract. 2023;248:154615. DOI:10.1016/j.prp.2023.154615
2. Louis B, Séverine L, Romain B, et al. Complete mitochondrial exploration of Echinococcus multilocularis from French alveolar echinococcosis patients. Int J Parasitol. 2023;53(10):555-64. DOI:10.1016/j.ijpara.2023.03.006
3. Monnink G, Stijnis C, van Delden O, et al. Percutaneous Versus Surgical Interventions for Hepatic Cystic Echinococcosis: A Systematic Review and Meta-Analysis. Cardiovasc Intervent Radiol. 2021;44:1689-96. DOI:10.1007/s00270-021-02911-4
4. Casulli A, Pane S, Randi F, et al. Primary cerebral cystic echinococcosis in a child from Roman countryside: Source attribution and scoping review of cases from the literature. PLoS Negl Trop Dis. 2023;17(9):e0011612. DOI:10.1371/journal.pntd.0011612
5. Meimand S, Sadeghpour A, Pakbaz M, et al. Cardiac Echinococcosis Associated with Other Organ Involvement: Report of Two Challenging Cases. CASE (Phila). 2020;5(1):33-8. DOI:10.1016/j.case.2020.09.008
6. Ирдеева В.А., Аракельян Р.С., Шендо Г.Л., и др. Клинико-эпидемиологические особенности эхинококкоза легких. Международный научно-исследовательский журнал. 2021;7(109) [Irdeeva VA, Arakelyan RS, Shendo GL, et al. Clinical and epidemiological features of pulmonary echinococcosis. International Research Journal. 2021;7(109) (in Russian)]. DOI:10.23670/IRJ.2021.109.7.051
7. Маслянинова А.Е., Шандригос Ю.Д., Мазурина Е.О. Клинико-эпидемиологические аспекты токсокароза человека. Международный научно-исследовательский журнал. 2023;11(137) [Maslyaninova AY, Shandrigos YD, Mazurina YO. Clinical and epidemiological aspects of human toxocarosis. International Research Journal. 2023;11(137) (in Russian)]. DOI:10.23670/IRJ.2023.137.107
8. Всемирная организация здравоохранения: эхинококкоз. Режим доступа: https://www.who.int/ru/news-room/fact-sheets/detail/echinococcosis. Ссылка активна на 20.02.2024 [WHO Newsletter: Echinococcosis. Available at: https://www.who.int/ru/news-room/fact-sheets/detail/echinococcosis. Accessed: 20.02.2024 (in Russian)].
9. Wen H, Vuitton L, Tuxun T, et al. Echinococcosis: Advances in the 21st Century. Clin Microbiol Rev. 2019;32(2):e00075-18. DOI:10.1128/CMR.00075-18
10. Weber T, Junghanss T, Stojković M. Pulmonary cystic echinococcosis. Curr Opin Infect Dis. 2023;36(5):318-25. DOI:10.1097/QCO.0000000000000962
11. Banisefid E, Baghernezhad K, Beheshti R, et al. Cardiac hydatid disease; a systematic review. BMC Infect Dis. 2023;23(1):600. DOI:10.1186/s12879-023-08576-3
12. Краснов А.О., Анищенко В.В., Краснов К.А., и др. Актуальное состояние вопросов диагностики и хирургического лечения эхинококкоза печени (обзор литературы). Acta Biomedica Scientifica. 2022;7(1):171-81 [Krasnov AO, Anischenko VV, Krasnov KA, et al. The curreby state of the issues of diagnosis and surgical treatment of liver echinococcosis (literature review). Acta Biomedica Scientifica. 2022;7(1):171-81 (in Russian)]. DOI:10.29413/ABS.2022-7.1.20
13. Tamarozzi F, Silva R, Fittipaldo V, et al. Serology for the diagnosis of human hepatic cystic echinococcosis and its relation with cyst staging: A systematic review of the literature with meta-analysis. PLoS Negl Trop Dis. 2021;15(4):e0009370. DOI:10.1371/journal.pntd.0009370
14. Agudelo H, Brunetti E, McCloskey C. Cystic Echinococcosis. J Clin Microbiol. 2016;54(3):518-23. DOI:10.1128/JCM.02420-15
15. Al-Saeedi M, Ramouz A, Khajeh E, et al. Endocystectomy as a conservative surgical treatment for hepatic cystic echinococcosis: A systematic review with single-arm meta-analysis. PLoS Negl Trop Dis. 2021;15(5):e0009365. DOI:10.1371/journal.pntd.0009365
16. Rawat S, Kumar R, Raja J, et al. Pulmonary hydatid cyst: Review of literature. J Family Med Prim Care. 2019;8(9):2774-8. DOI:10.4103/jfmpc.jfmpc_624_19
17. Yan F, Huo Q, Abudureheman M, et al. Surgical treatment and outcome of cardiac cystic echinococcosis. Eur J Cardiothorac Surg. 2015;47(6):1053-8. DOI:10.1093/ejcts/ezu323
18. Fennira S, Kamoun S, Besbes B, et al. Cardiac hydatid cyst in the interventricular septum: A literature review. Int J Infect Dis. 2019;88:120-6. DOI:10.1016/j.ijid.2019.09.004
19. Rabiou S, Lakranbi M, Ouadnouni Y, et al. Surgical management of hydatid Bilio-bronchial fistula by exclusive thoracotomy. Int J Surg. 2017;41:112-8. DOI:10.1016/j.ijsu.2017.03.074
20. Поздеева О.К. Медицинская паразитология: гельминты. Практическое руководство. М.: ГЭОТАР-Медиа, 2023 [Pozdeeva OK. Meditsinskaia parazitologiia: gelminty. Prakticheskoe rukovodstvo. Moscow: GEOTAR-Media, 2023 (in Russian)]. DOI:10.33029/9704-7685-7-MPH-2023-1-400
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1. Giuseppe M, Alessandro B, Marco S, et al. An unexpected guest: Pulmonary echinococcosis diagnosed by intraoperative frozen section examination. A case report and literature review. Pathol Res Pract. 2023;248:154615. DOI:10.1016/j.prp.2023.154615
2. Louis B, Séverine L, Romain B, et al. Complete mitochondrial exploration of Echinococcus multilocularis from French alveolar echinococcosis patients. Int J Parasitol. 2023;53(10):555-64. DOI:10.1016/j.ijpara.2023.03.006
3. Monnink G, Stijnis C, van Delden O, et al. Percutaneous Versus Surgical Interventions for Hepatic Cystic Echinococcosis: A Systematic Review and Meta-Analysis. Cardiovasc Intervent Radiol. 2021;44:1689-96. DOI:10.1007/s00270-021-02911-4
4. Casulli A, Pane S, Randi F, et al. Primary cerebral cystic echinococcosis in a child from Roman countryside: Source attribution and scoping review of cases from the literature. PLoS Negl Trop Dis. 2023;17(9):e0011612. DOI:10.1371/journal.pntd.0011612
5. Meimand S, Sadeghpour A, Pakbaz M, et al. Cardiac Echinococcosis Associated with Other Organ Involvement: Report of Two Challenging Cases. CASE (Phila). 2020;5(1):33-8. DOI:10.1016/j.case.2020.09.008
6. Irdeeva VA, Arakelyan RS, Shendo GL, et al. Clinical and epidemiological features of pulmonary echinococcosis. International Research Journal. 2021;7(109) (in Russian). DOI:10.23670/IRJ.2021.109.7.051
7. Maslyaninova AY, Shandrigos YD, Mazurina YO. Clinical and epidemiological aspects of human toxocarosis. International Research Journal. 2023;11(137) (in Russian). DOI:10.23670/IRJ.2023.137.107
8. WHO Newsletter: Echinococcosis. Available at: https://www.who.int/ru/news-room/fact-sheets/detail/echinococcosis. Accessed: 20.02.2024 (in Russian).
9. Wen H, Vuitton L, Tuxun T, et al. Echinococcosis: Advances in the 21st Century. Clin Microbiol Rev. 2019;32(2):e00075-18. DOI:10.1128/CMR.00075-18
10. Weber T, Junghanss T, Stojković M. Pulmonary cystic echinococcosis. Curr Opin Infect Dis. 2023;36(5):318-25. DOI:10.1097/QCO.0000000000000962
11. Banisefid E, Baghernezhad K, Beheshti R, et al. Cardiac hydatid disease; a systematic review. BMC Infect Dis. 2023;23(1):600. DOI:10.1186/s12879-023-08576-3
12. Krasnov AO, Anischenko VV, Krasnov KA, et al. The curreby state of the issues of diagnosis and surgical treatment of liver echinococcosis (literature review). Acta Biomedica Scientifica. 2022;7(1):171-81 (in Russian). DOI:10.29413/ABS.2022-7.1.20
13. Tamarozzi F, Silva R, Fittipaldo V, et al. Serology for the diagnosis of human hepatic cystic echinococcosis and its relation with cyst staging: A systematic review of the literature with meta-analysis. PLoS Negl Trop Dis. 2021;15(4):e0009370. DOI:10.1371/journal.pntd.0009370
14. Agudelo H, Brunetti E, McCloskey C. Cystic Echinococcosis. J Clin Microbiol. 2016;54(3):518-23. DOI:10.1128/JCM.02420-15
15. Al-Saeedi M, Ramouz A, Khajeh E, et al. Endocystectomy as a conservative surgical treatment for hepatic cystic echinococcosis: A systematic review with single-arm meta-analysis. PLoS Negl Trop Dis. 2021;15(5):e0009365. DOI:10.1371/journal.pntd.0009365
16. Rawat S, Kumar R, Raja J, et al. Pulmonary hydatid cyst: Review of literature. J Family Med Prim Care. 2019;8(9):2774-8. DOI:10.4103/jfmpc.jfmpc_624_19
17. Yan F, Huo Q, Abudureheman M, et al. Surgical treatment and outcome of cardiac cystic echinococcosis. Eur J Cardiothorac Surg. 2015;47(6):1053-8. DOI:10.1093/ejcts/ezu323
18. Fennira S, Kamoun S, Besbes B, et al. Cardiac hydatid cyst in the interventricular septum: A literature review. Int J Infect Dis. 2019;88:120-6. DOI:10.1016/j.ijid.2019.09.004
19. Rabiou S, Lakranbi M, Ouadnouni Y, et al. Surgical management of hydatid Bilio-bronchial fistula by exclusive thoracotomy. Int J Surg. 2017;41:112-8. DOI:10.1016/j.ijsu.2017.03.074
20. Pozdeeva OK. Meditsinskaia parazitologiia: gelminty. Prakticheskoe rukovodstvo. Moscow: GEOTAR-Media, 2023 (in Russian). DOI:10.33029/9704-7685-7-MPH-2023-1-400
1ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России, Москва, Россия; 2АО «Группа компаний "МЕДСИ"», Москва, Россия; 3ГБУЗ «Государственная клиническая больница №31 им. акад. Г.М. Савельевой» Департамента здравоохранения г. Москвы, Москва, Россия
*grigorevskaia.as@medsigroup.ru
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Elena V. Reznik1–3, Maksim D. Iarovoi1, Svetlana A. Zavialova2, Shahrizat M. Umakhanova1, Aleksandra S. Grigorievskaya*1,2, Oleg I. Makolin2, Igor V. Semeniakin2
1Pirogov Russian National Research Medical University, Moscow, Russia; 2Medsi group Joint Stock Company, Moscow, Russia; 3Savel'eva City Clinical Hospital №31, Moscow, Russia
*grigorevskaia.as@medsigroup.ru