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Возможности улучшения госпитального и отдаленного прогнозов при нестабильной стенокардии
Возможности улучшения госпитального и отдаленного прогнозов при нестабильной стенокардии
Бойцов С.А., Проваторов С.И. Возможности улучшения госпитального и отдаленного прогнозов при нестабильной стенокардии. Терапевтический архив. 2024;96(1):5–10.
DOI: 10.26442/00403660.2024.01.202555
© ООО «КОНСИЛИУМ МЕДИКУМ», 2024 г.
DOI: 10.26442/00403660.2024.01.202555
© ООО «КОНСИЛИУМ МЕДИКУМ», 2024 г.
________________________________________________
Материалы доступны только для специалистов сферы здравоохранения. Авторизуйтесь или зарегистрируйтесь.
Аннотация
Нестабильная стенокардия (НС) представляет собой вариант течения острого коронарного синдрома (ОКС), при котором не развивается ишемическое повреждение миокарда. Основным критерием диагностики НС при ОКС является отсутствие изменений концентрации кардиоспецифического тропонина в крови больного. При небольшом объеме поражения выявление инфаркта миокарда у больного с помощью низкочувствительных тестов, способствующих определению уровня кардиоспецифического тропонина в крови, может быть затруднено. Соответственно, это может приводить к гипердиагностике НС у пациентов с ОКС без подъема сегмента ST. Оптимальная медикаментозная терапия и своевременно выполненная реваскуляризация коронарных артерий существенно снижают риск смерти и развития инфаркта миокарда в госпитальном и отдаленном периодах у пациентов с НС. Диспансерное наблюдение и получение льготного лекарственного обеспечения могут снизить смертность в отсроченном периоде после перенесенного эпизода НС.
Ключевые слова: нестабильная стенокардия, острый коронарный синдром, инфаркт миокарда, оптимальная медикаментозная терапия, сердечный тропонин, коронарные артерии, реваскуляризация, диспансерное наблюдение, прогноз
Keywords: unstable angina, acute coronary syndrome, myocardial infarction, optimal drug therapy, cardiac troponin, coronary arteries, revascularization, outpatient follow-up, prognosis
Ключевые слова: нестабильная стенокардия, острый коронарный синдром, инфаркт миокарда, оптимальная медикаментозная терапия, сердечный тропонин, коронарные артерии, реваскуляризация, диспансерное наблюдение, прогноз
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Keywords: unstable angina, acute coronary syndrome, myocardial infarction, optimal drug therapy, cardiac troponin, coronary arteries, revascularization, outpatient follow-up, prognosis
Полный текст
Список литературы
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2. Conti CR, Greene B, Pitt B, et al. Coronary surgery in unstable angina pectoris. Circulation. 1971;44(Suppl. 2):154.
3. Byrne RA, Rossello X, Coughlan JJ, et al. 2023 ESC Guidelines for the management of acute coronary syndromes. Eur Heart J. 2023;44(38):3720-826. DOI:10.1093/eurheartj/ehad191
4. Harper RW, Kennedy G, DeSanctis RW, Hutter AM Jr. The incidence and pattern of angina prior to acute myocardial infarction: a study of 577 cases. Am Heart J. 1979;97(2):178-83. DOI:10.1016/0002-8703(79)90353-3
5. Kloner RA, Shook T, Antman EM, et al. Prospective temporal analysis of the onset of preinfarction angina versus outcome: an ancillary study in TIMI-9B. Circulation.
1998;97(11):1042-5. DOI:10.1161/01.cir.97.11.1042
6. Thom T, Haase N, Rosamond W, et al. Heart disease and stroke statistics – 2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2006;113(6):e85-151. DOI:10.1161/CIRCULATIONAHA.105.171600
7. Mozaffarian D, Benjamin EJ, Go AS, et al. Heart disease and stroke statistics – 2016 update: a report from the American Heart Association. Circulation. 2016;133(4):e38-360. DOI:10.1161/CIR.0000000000000350
8. Barbarash OL, Duplyakov DV, Zateischikov DA, et al. 2020 Clinical practice guidelines for Acute coronary syndrome without ST segment elevation. Russian Journal of Cardiology. 2021;26(4):4449 (in Russian). DOI:10.15829/1560-4071-2021-4449
9. Apple FS, Ler R, Murakami MM. Determination of 19 cardiac troponin I and T assay 99th percentile values from a common presumably healthy population. Clin Chem. 2012;58(11):1574-81. DOI:10.1373/clinchem.2012.192716
10. Jhund PS, Claggett BL, Voors AA, et al. Elevation in high-sensitivity troponin T in heart failure and preserved ejection fraction and influence of treatment with the angiotensin receptor neprilysin inhibitor LCZ696. Circ Heart Fail. 2014;7(6):953-9. DOI:10.1161/CIRCHEARTFAILURE.114.001427
11. deFilippi C, Seliger SL, Kelley W, et al. Interpreting cardiac troponin results from high-sensitivity assays in chronic kidney disease without acute coronary syndrome. Clin Chem. 2012;58(9):1342-51. DOI:10.1373/clinchem.2012.185322
12. Eggers KM, Jernberg T, Lindahl B. Unstable Angina in the Era of Cardiac Troponin Assays with Improved Sensitivity – a Clinical Dilemma. Am J Med. 2017;130(12):1423-30.e5. DOI:10.1016/j.amjmed.2017.05.037
13. Braunwald E. Unstable angina. A classification. Circulation. 1989;80(2):410-4. DOI:10.1161/01.cir.80.2.410
14. Hamm CW, Braunwald E. A classification of unstable angina revisited. Circulation. 2000;102(1):118-22. DOI:10.1161/01.CIR.102.1.118
15. Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction (2018). Eur Heart J. 2019;40(3):237-69. DOI:10.1093/eurheartj/ehy462
16. Katus HA, Giannitsis E. Prognostic Value of Serum Troponin T in Unstable Angina. Clin Chem. 2018;64(2):396-7. DOI:10.1373/clinchem.2017.272799
17. van Miltenburg-van Zijl AJ, Simoons ML, Veerhoek RJ, Bossuyt PM. Incidence and follow-up of Braunwald subgroups in unstable angina pectoris. J Am Coll Cardiol.
1995;25(6):1286-92. DOI:10.1016/0735-1097(95)00009-S
18. Beigel R, Matetzky S, Gavrielov-Yusim N, et al. Predictors of high-risk angiographic findings in patients with non-ST-segment elevation acute coronary syndrome. Catheter Cardiovasc Interv. 2014;83(5):677-83. DOI:10.1002/ccd.25081
19. Butt JH, Kofoed KF, Kelbæk H, et al. Importance of Risk Assessment in Timing of Invasive Coronary Evaluation and Treatment of Patients With Non-ST-Segment-Elevation Acute Coronary Syndrome: Insights From the VERDICT Trial. J Am Heart Assoc. 2021;10(19):e022333. DOI:10.1161/JAHA.121.022333
20. Shah BN, Balaji G, Alhajiri A, et al. Incremental diagnostic and prognostic value of contemporary stress echocardiography in a chest pain unit: mortality and morbidity outcomes from a real-world setting. Circ Cardiovasc Imaging. 2013;6(2):202-9. DOI:10.1161/CIRCIMAGING.112.980797
21. Gaibazzi N, Reverberi C, Badano L. Usefulness of contrast stress-echocardiography or exercise-electrocardiography to predict long-term acute coronary syndromes in patients presenting with chest pain without electrocardiographic abnormalities or 12-hour troponin elevation. Am J Cardiol. 2011;107(2):161-7. DOI:10.1016/j.amjcard.2010.08.066
22. Linde JJ, Kelbek H, Hansen TF, et al. Coronary CT Angiography in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome. J Am Coll Cardiol. 2020;75(5):453-63. DOI:10.1016/j.jacc.2019.12.012
23. Mehta SR, Granger CB, Boden WE, et al. Early versus delayed invasive intervention in acute coronary syndromes. N Engl J Med. 2009;360(21):2165-75. DOI:10.1056/NEJMoa0807986
24. Desperak P, Hawranek M, Gąsior P, et al. Long-term outcomes of patients with multivessel coronary artery disease presenting non-ST-segment elevation acute coronary syndromes. Cardiol J. 2019;26(2):157-68. DOI:10.5603/CJ.a2017.0110
25. Garcia S, Sandoval Y, Roukoz H, et al. Outcomes after complete versus incomplete revascularization of patients with multivessel coronary artery disease: a meta-analysis of 89,883 patients enrolled in randomized clinical trials and observational studies. J Am Coll Cardiol. 2013;62(16):1421-31. DOI:10.1016/j.jacc.2013.05.033
26. Généreux P, Palmerini T, Caixeta A, et al. Quantification and impact of untreated coronary artery disease after percutaneous coronary intervention: the residual SYNTAX (Synergy Between PCI with Taxus and Cardiac Surgery) score. J Am Coll Cardiol. 2012;59(24):2165-74. DOI:10.1016/j.jacc.2012.03.010
27. Farmer D, Jimenez E. Re-evaluating the Role of CABG in Acute Coronary Syndromes. Curr Cardiol Rep. 2020;22(11):148. DOI:10.1007/s11886-020-01386-y
28. Ramanathan K, Abel JG, Park JE, et al. Surgical Versus Percutaneous Coronary Revascularization in Patients With Diabetes and Acute Coronary Syndromes. J Am Coll Cardiol. 2017;70(24):2995-3006. DOI:10.1016/j.jacc.2017.10.029
29. Benedetto U, Sinha S, Mulla A, et al. Implications of elevated troponin on time-to-surgery in non-ST elevation myocardial infarction (NIHR Health Informatics Collaborative: TROP-CABG study). Int J Cardiol. 2022;362:14-9. DOI:10.1016/j.ijcard.2022.04.067
30. Jang JS, Jin HY, Seo JS, et al. Meta-analysis of multivessel versus culprit-only percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndrome and multivessel coronary disease. Am J Cardiol. 2015;115(8):1027-32. DOI:10.1016/j.amjcard.2015.01.530
31. Gazes PC, Mobley Jr. EM, Faris Jr. HM, et al. Preinfarctional (unstable) angina – a prospective study – ten year follow-up. Prognostic significance of electrocardiographic changes. Circulation. 1973;48(2):331-7. DOI:10.1161/01.CIR.48.2.331
32. Cairns JA, Gent M, Singer J, et al. Aspirin, sulfinpyrazone, or both in unstable angina. Results of a Canadian multicenter trial. N Engl J Med. 1985;313(22):1369-75. DOI:10.1056/NEJM198511283132201
33. Mulcahy R, Conroy R, Katz R, Fitzpatrick M. Does intensive medical therapy influence the outcome in unstable angina? Clin Cardiol. 1990;13(10):687-9. DOI:10.1002/clc.4960131003
34. Valentín V. Clopidogrel in acute coronary syndromes with non-ST elevation. Clinical implications of the CURE trial. Rev Esp Cardiol. 2001;54(10):1127-34 (in Spanish).
35. Baigent C, Blackwell L, Emberson J, et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet. 2010;376(9753):1670-81. DOI:10.1016/S0140-6736(10)61350-5
36. Erlikh AD. Twelve months outcomes in patients with acute coronary syndrome, by the national registry RECORD-3. Russian Journal of Cardiology. 2018;3:23-30 (in Russian. DOI:10.15829/1560-4071-2018-3-23-30
37. Shchinova AM, Potekhina AV, Dolgusheva YuA, et al. Comparison of in-hospital and long-term mortality and assessment of their predictors in patients with myocardial infarction and unstable angina. Almanac of Clinical Medicine. 2023;51(2):77-85 (in Russian). DOI:10.18786/2072-0505-2023-51-013
38. Roos A, Edgren G, Holzmann MJ. Unstable Angina Pectoris With Myocardial Injury Versus Myocardial Infarction in the Era of High-Sensitivity Cardiac Troponin. Am J Cardiol. 2022;169:32-41. DOI:10.1016/j.amjcard.2021.12.044
39. Katus HA, Giannitsis E. Prognostic Value of Serum Troponin T in Unstable Angina. Clin Chem. 2018;64(2):396-7. DOI:10.1373/clinchem.2017.272799
40. Sasaki S, Inoue K, Shiozaki M, et al. One-Year Outcome of Patients with Chest Pain in the Rule-Out Group According to the 0-Hour/1-Hour Algorithm. Int Heart J. 2023;64(4):590-5. DOI:10.1536/ihj.23-076
41. Shchinova AM, Potekhina AV, Dolgusheva YuA, et al. Comparison of the effectiveness of secondary prevention and long-term mortality after acute coronary syndrome depending on the form of follow-up. Russian Journal of Cardiology. 2023;28(7S):9-10 (in Russian). DOI:10.15829/1560-4071-2023-7S
42. Chow CK, Brieger D, Ryan M, et al. Secondary prevention therapies in acute coronary syndrome and relation to outcomes: observational study. Heart Asia. 2019;11(1):e 011122. DOI:10.1136/heartasia-2018-011122
43. Ob utverzhdenii poriadka provedeniia dispansernogo nabliudeniia za vzroslymi: prikaz Minzdrava Rossii ot 15.03.2022 g. №168n. Available at: https://rg.ru/documents/2022/04/22/minzdrav-prikaz168-site-dok.html. Accessed: 03.12.2023 (in Russian).
44. Ob utverzhdenii perechnia lekarstvennykh preparatov dlia meditsinskogo primeneniia v tseliakh obespecheniia v ambulatornykh usloviiakh lits, nakhodiashchikhsia pod dispansernym nabliudeniem, kotorye perenesli ostroe narushenie mozgovogo krovoobrashcheniia, infarkt miokarda, a takzhe kotorym vypolneny aortokoronarnoe shuntirovanie, angioplastika koronarnykh arterii so stentirovaniem i kateternaia abliatsiia po povodu serdechno-sosudistykh zabolevanii, v techenie 2 let s daty postanovki diagnoza i (ili) vypolneniia khirurgicheskogo vmeshatel'stva: prikaz Minzdrava Rossii ot 29.09.2022. №639n. Available at: https://rg.ru/documents/2022/10/28/minzdrav-prikaz639-site-dok.html. Accessed: 03.12.2023 (in Russian).
2. Conti CR, Greene B, Pitt B, et al. Coronary surgery in unstable angina pectoris. Circulation. 1971;44(Suppl. 2):154.
3. Byrne RA, Rossello X, Coughlan JJ, et al. 2023 ESC Guidelines for the management of acute coronary syndromes. Eur Heart J. 2023;44(38):3720-826. DOI:10.1093/eurheartj/ehad191
4. Harper RW, Kennedy G, DeSanctis RW, Hutter AM Jr. The incidence and pattern of angina prior to acute myocardial infarction: a study of 577 cases. Am Heart J. 1979;97(2):178-83. DOI:10.1016/0002-8703(79)90353-3
5. Kloner RA, Shook T, Antman EM, et al. Prospective temporal analysis of the onset of preinfarction angina versus outcome: an ancillary study in TIMI-9B. Circulation.
1998;97(11):1042-5. DOI:10.1161/01.cir.97.11.1042
6. Thom T, Haase N, Rosamond W, et al. Heart disease and stroke statistics – 2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2006;113(6):e85-151. DOI:10.1161/CIRCULATIONAHA.105.171600
7. Mozaffarian D, Benjamin EJ, Go AS, et al. Heart disease and stroke statistics – 2016 update: a report from the American Heart Association. Circulation. 2016;133(4):e38-360. DOI:10.1161/CIR.0000000000000350
8. Барбараш О.Л., Дупляков Д.В., Затейщиков Д.А., и др. Острый коронарный синдром без подъема сегмента ST электрокардиограммы. Клинические рекомендации 2020. Российский кардиологический журнал. 2021;26(4):4449 [Barbarash OL, Duplyakov DV, Zateischikov DA, et al. 2020 Clinical practice guidelines for Acute coronary syndrome without ST segment elevation. Russian Journal of Cardiology. 2021;26(4):4449 (in Russian)]. DOI:10.15829/1560-4071-2021-4449
9. Apple FS, Ler R, Murakami MM. Determination of 19 cardiac troponin I and T assay 99th percentile values from a common presumably healthy population. Clin Chem. 2012;58(11):1574-81. DOI:10.1373/clinchem.2012.192716
10. Jhund PS, Claggett BL, Voors AA, et al. Elevation in high-sensitivity troponin T in heart failure and preserved ejection fraction and influence of treatment with the angiotensin receptor neprilysin inhibitor LCZ696. Circ Heart Fail. 2014;7(6):953-9. DOI:10.1161/CIRCHEARTFAILURE.114.001427
11. deFilippi C, Seliger SL, Kelley W, et al. Interpreting cardiac troponin results from high-sensitivity assays in chronic kidney disease without acute coronary syndrome. Clin Chem. 2012;58(9):1342-51. DOI:10.1373/clinchem.2012.185322
12. Eggers KM, Jernberg T, Lindahl B. Unstable Angina in the Era of Cardiac Troponin Assays with Improved Sensitivity – a Clinical Dilemma. Am J Med. 2017;130(12):1423-30.e5. DOI:10.1016/j.amjmed.2017.05.037
13. Braunwald E. Unstable angina. A classification. Circulation. 1989;80(2):410-4. DOI:10.1161/01.cir.80.2.410
14. Hamm CW, Braunwald E. A classification of unstable angina revisited. Circulation. 2000;102(1):118-22. DOI:10.1161/01.CIR.102.1.118
15. Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction (2018). Eur Heart J. 2019;40(3):237-69. DOI:10.1093/eurheartj/ehy462
16. Katus HA, Giannitsis E. Prognostic Value of Serum Troponin T in Unstable Angina. Clin Chem. 2018;64(2):396-7. DOI:10.1373/clinchem.2017.272799
17. van Miltenburg-van Zijl AJ, Simoons ML, Veerhoek RJ, Bossuyt PM. Incidence and follow-up of Braunwald subgroups in unstable angina pectoris. J Am Coll Cardiol.
1995;25(6):1286-92. DOI:10.1016/0735-1097(95)00009-S
18. Beigel R, Matetzky S, Gavrielov-Yusim N, et al. Predictors of high-risk angiographic findings in patients with non-ST-segment elevation acute coronary syndrome. Catheter Cardiovasc Interv. 2014;83(5):677-83. DOI:10.1002/ccd.25081
19. Butt JH, Kofoed KF, Kelbæk H, et al. Importance of Risk Assessment in Timing of Invasive Coronary Evaluation and Treatment of Patients With Non-ST-Segment-Elevation Acute Coronary Syndrome: Insights From the VERDICT Trial. J Am Heart Assoc. 2021;10(19):e022333. DOI:10.1161/JAHA.121.022333
20. Shah BN, Balaji G, Alhajiri A, et al. Incremental diagnostic and prognostic value of contemporary stress echocardiography in a chest pain unit: mortality and morbidity outcomes from a real-world setting. Circ Cardiovasc Imaging. 2013;6(2):202-9. DOI:10.1161/CIRCIMAGING.112.980797
21. Gaibazzi N, Reverberi C, Badano L. Usefulness of contrast stress-echocardiography or exercise-electrocardiography to predict long-term acute coronary syndromes in patients presenting with chest pain without electrocardiographic abnormalities or 12-hour troponin elevation. Am J Cardiol. 2011;107(2):161-7. DOI:10.1016/j.amjcard.2010.08.066
22. Linde JJ, Kelbek H, Hansen TF, et al. Coronary CT Angiography in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome. J Am Coll Cardiol. 2020;75(5):453-63. DOI:10.1016/j.jacc.2019.12.012
23. Mehta SR, Granger CB, Boden WE, et al. Early versus delayed invasive intervention in acute coronary syndromes. N Engl J Med. 2009;360(21):2165-75. DOI:10.1056/NEJMoa0807986
24. Desperak P, Hawranek M, Gąsior P, et al. Long-term outcomes of patients with multivessel coronary artery disease presenting non-ST-segment elevation acute coronary syndromes. Cardiol J. 2019;26(2):157-68. DOI:10.5603/CJ.a2017.0110
25. Garcia S, Sandoval Y, Roukoz H, et al. Outcomes after complete versus incomplete revascularization of patients with multivessel coronary artery disease: a meta-analysis of 89,883 patients enrolled in randomized clinical trials and observational studies. J Am Coll Cardiol. 2013;62(16):1421-31. DOI:10.1016/j.jacc.2013.05.033
26. Généreux P, Palmerini T, Caixeta A, et al. Quantification and impact of untreated coronary artery disease after percutaneous coronary intervention: the residual SYNTAX (Synergy Between PCI with Taxus and Cardiac Surgery) score. J Am Coll Cardiol. 2012;59(24):2165-74. DOI:10.1016/j.jacc.2012.03.010
27. Farmer D, Jimenez E. Re-evaluating the Role of CABG in Acute Coronary Syndromes. Curr Cardiol Rep. 2020;22(11):148. DOI:10.1007/s11886-020-01386-y
28. Ramanathan K, Abel JG, Park JE, et al. Surgical Versus Percutaneous Coronary Revascularization in Patients With Diabetes and Acute Coronary Syndromes. J Am Coll Cardiol. 2017;70(24):2995-3006. DOI:10.1016/j.jacc.2017.10.029
29. Benedetto U, Sinha S, Mulla A, et al. Implications of elevated troponin on time-to-surgery in non-ST elevation myocardial infarction (NIHR Health Informatics Collaborative: TROP-CABG study). Int J Cardiol. 2022;362:14-9. DOI:10.1016/j.ijcard.2022.04.067
30. Jang JS, Jin HY, Seo JS, et al. Meta-analysis of multivessel versus culprit-only percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndrome and multivessel coronary disease. Am J Cardiol. 2015;115(8):1027-32. DOI:10.1016/j.amjcard.2015.01.530
31. Gazes PC, Mobley Jr. EM, Faris Jr. HM, et al. Preinfarctional (unstable) angina – a prospective study – ten year follow-up. Prognostic significance of electrocardiographic changes. Circulation. 1973;48(2):331-7. DOI:10.1161/01.CIR.48.2.331
32. Cairns JA, Gent M, Singer J, et al. Aspirin, sulfinpyrazone, or both in unstable angina. Results of a Canadian multicenter trial. N Engl J Med. 1985;313(22):1369-75. DOI:10.1056/NEJM198511283132201
33. Mulcahy R, Conroy R, Katz R, Fitzpatrick M. Does intensive medical therapy influence the outcome in unstable angina? Clin Cardiol. 1990;13(10):687-9. DOI:10.1002/clc.4960131003
34. Valentín V. Clopidogrel in acute coronary syndromes with non-ST elevation. Clinical implications of the CURE trial. Rev Esp Cardiol. 2001;54(10):1127-34 (in Spanish).
35. Baigent C, Blackwell L, Emberson J, et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet. 2010;376(9753):1670-81. DOI:10.1016/S0140-6736(10)61350-5
36. Эрлих А.Д. 12-месячные исходы у пациентов с острым коронарным синдромом, включенных в российский регистр «РЕКОРД-3». Российский кардиологический журнал. 2018;(3):23-30 [Erlikh AD. Twelve months outcomes in patients with acute coronary syndrome, by the national registry RECORD-3. Russian Journal of Cardiology. 2018;3:23-30 (in Russian)]. DOI:10.15829/1560-4071-2018-3-23-30
37. Щинова А.М., Потехина А.В., Долгушева Ю.А. Cопоставление госпитальной и отдаленной летальности и оценка их предикторов у пациентов, перенесших инфаркт миокарда и нестабильную стенокардию. Альманах клинической медицины. 2023;51(2):77-85 [Shchinova AM, Potekhina AV, Dolgusheva YuA, et al. Comparison of in-hospital and long-term mortality and assessment of their predictors in patients with myocardial infarction and unstable angina. Almanac of Clinical Medicine. 2023;51(2):77-85 (in Russian)]. DOI:10.18786/2072-0505-2023-51-013
38. Roos A, Edgren G, Holzmann MJ. Unstable Angina Pectoris With Myocardial Injury Versus Myocardial Infarction in the Era of High-Sensitivity Cardiac Troponin. Am J Cardiol. 2022;169:32-41. DOI:10.1016/j.amjcard.2021.12.044
39. Katus HA, Giannitsis E. Prognostic Value of Serum Troponin T in Unstable Angina. Clin Chem. 2018;64(2):396-7. DOI:10.1373/clinchem.2017.272799
40. Sasaki S, Inoue K, Shiozaki M, et al. One-Year Outcome of Patients with Chest Pain in the Rule-Out Group According to the 0-Hour/1-Hour Algorithm. Int Heart J. 2023;64(4):590-5. DOI:10.1536/ihj.23-076
41. Щинова А.М., Потехина А.В., Долгушева Ю.А., и др. Сопоставление эффективности вторичной профилактики и отдаленной летальности после перенесенного острого коронарного синдрома в зависимости от формы диспансерного наблюдения. Российский кардиологический журнал. 2023;28(7S):9-10 [Shchinova AM, Potekhina AV, Dolgusheva YuA, et al. Comparison of the effectiveness of secondary prevention and long-term mortality after acute coronary syndrome depending on the form of follow-up. Russian Journal of Cardiology. 2023;28(7S):9-10 (in Russian)]. DOI:10.15829/1560-4071-2023-7S
42. Chow CK, Brieger D, Ryan M, et al. Secondary prevention therapies in acute coronary syndrome and relation to outcomes: observational study. Heart Asia. 2019;11(1):e 011122. DOI:10.1136/heartasia-2018-011122
43. Об утверждении порядка проведения диспансерного наблюдения за взрослыми: приказ Минздрава России от 15.03.2022 г. №168н. Режим доступа: https://rg.ru/documents/2022/04/22/minzdrav-prikaz168-site-dok.html. Ссылка активна на 03.12.2023 [Ob utverzhdenii poriadka provedeniia dispansernogo nabliudeniia za vzroslymi: prikaz Minzdrava Rossii ot 15.03.2022 g. №168n. Available at: https://rg.ru/documents/2022/04/22/minzdrav-prikaz168-site-dok.html. Accessed: 03.12.2023 (in Russian)].
44. Об утверждении перечня лекарственных препаратов для медицинского применения в целях обеспечения в амбулаторных условиях лиц, находящихся под диспансерным наблюдением, которые перенесли острое нарушение мозгового кровообращения, инфаркт миокарда, а также которым выполнены аортокоронарное шунтирование, ангиопластика коронарных артерий со стентированием и катетерная абляция по поводу сердечно-сосудистых заболеваний, в течение 2 лет с даты постановки диагноза и (или) выполнения хирургического вмешательства: приказ Минздрава России от 29.09.2022. №639н. Режим доступа: https://rg.ru/documents/2022/10/28/minzdrav-prikaz639-site-dok.html. Ссылка активна на 03.12.2023 [Ob utverzhdenii perechnia lekarstvennykh preparatov dlia meditsinskogo primeneniia v tseliakh obespecheniia v ambulatornykh usloviiakh lits, nakhodiashchikhsia pod dispansernym nabliudeniem, kotorye perenesli ostroe narushenie mozgovogo krovoobrashcheniia, infarkt miokarda, a takzhe kotorym vypolneny aortokoronarnoe shuntirovanie, angioplastika koronarnykh arterii so stentirovaniem i kateternaia abliatsiia po povodu serdechno-sosudistykh zabolevanii, v techenie 2 let s daty postanovki diagnoza i (ili) vypolneniia khirurgicheskogo vmeshatel'stva: prikaz Minzdrava Rossii ot 29.09.2022. №639n. Available at: https://rg.ru/documents/2022/10/28/minzdrav-prikaz639-site-dok.html. Accessed: 03.12.2023 (in Russian)].
________________________________________________
2. Conti CR, Greene B, Pitt B, et al. Coronary surgery in unstable angina pectoris. Circulation. 1971;44(Suppl. 2):154.
3. Byrne RA, Rossello X, Coughlan JJ, et al. 2023 ESC Guidelines for the management of acute coronary syndromes. Eur Heart J. 2023;44(38):3720-826. DOI:10.1093/eurheartj/ehad191
4. Harper RW, Kennedy G, DeSanctis RW, Hutter AM Jr. The incidence and pattern of angina prior to acute myocardial infarction: a study of 577 cases. Am Heart J. 1979;97(2):178-83. DOI:10.1016/0002-8703(79)90353-3
5. Kloner RA, Shook T, Antman EM, et al. Prospective temporal analysis of the onset of preinfarction angina versus outcome: an ancillary study in TIMI-9B. Circulation.
1998;97(11):1042-5. DOI:10.1161/01.cir.97.11.1042
6. Thom T, Haase N, Rosamond W, et al. Heart disease and stroke statistics – 2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2006;113(6):e85-151. DOI:10.1161/CIRCULATIONAHA.105.171600
7. Mozaffarian D, Benjamin EJ, Go AS, et al. Heart disease and stroke statistics – 2016 update: a report from the American Heart Association. Circulation. 2016;133(4):e38-360. DOI:10.1161/CIR.0000000000000350
8. Barbarash OL, Duplyakov DV, Zateischikov DA, et al. 2020 Clinical practice guidelines for Acute coronary syndrome without ST segment elevation. Russian Journal of Cardiology. 2021;26(4):4449 (in Russian). DOI:10.15829/1560-4071-2021-4449
9. Apple FS, Ler R, Murakami MM. Determination of 19 cardiac troponin I and T assay 99th percentile values from a common presumably healthy population. Clin Chem. 2012;58(11):1574-81. DOI:10.1373/clinchem.2012.192716
10. Jhund PS, Claggett BL, Voors AA, et al. Elevation in high-sensitivity troponin T in heart failure and preserved ejection fraction and influence of treatment with the angiotensin receptor neprilysin inhibitor LCZ696. Circ Heart Fail. 2014;7(6):953-9. DOI:10.1161/CIRCHEARTFAILURE.114.001427
11. deFilippi C, Seliger SL, Kelley W, et al. Interpreting cardiac troponin results from high-sensitivity assays in chronic kidney disease without acute coronary syndrome. Clin Chem. 2012;58(9):1342-51. DOI:10.1373/clinchem.2012.185322
12. Eggers KM, Jernberg T, Lindahl B. Unstable Angina in the Era of Cardiac Troponin Assays with Improved Sensitivity – a Clinical Dilemma. Am J Med. 2017;130(12):1423-30.e5. DOI:10.1016/j.amjmed.2017.05.037
13. Braunwald E. Unstable angina. A classification. Circulation. 1989;80(2):410-4. DOI:10.1161/01.cir.80.2.410
14. Hamm CW, Braunwald E. A classification of unstable angina revisited. Circulation. 2000;102(1):118-22. DOI:10.1161/01.CIR.102.1.118
15. Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction (2018). Eur Heart J. 2019;40(3):237-69. DOI:10.1093/eurheartj/ehy462
16. Katus HA, Giannitsis E. Prognostic Value of Serum Troponin T in Unstable Angina. Clin Chem. 2018;64(2):396-7. DOI:10.1373/clinchem.2017.272799
17. van Miltenburg-van Zijl AJ, Simoons ML, Veerhoek RJ, Bossuyt PM. Incidence and follow-up of Braunwald subgroups in unstable angina pectoris. J Am Coll Cardiol.
1995;25(6):1286-92. DOI:10.1016/0735-1097(95)00009-S
18. Beigel R, Matetzky S, Gavrielov-Yusim N, et al. Predictors of high-risk angiographic findings in patients with non-ST-segment elevation acute coronary syndrome. Catheter Cardiovasc Interv. 2014;83(5):677-83. DOI:10.1002/ccd.25081
19. Butt JH, Kofoed KF, Kelbæk H, et al. Importance of Risk Assessment in Timing of Invasive Coronary Evaluation and Treatment of Patients With Non-ST-Segment-Elevation Acute Coronary Syndrome: Insights From the VERDICT Trial. J Am Heart Assoc. 2021;10(19):e022333. DOI:10.1161/JAHA.121.022333
20. Shah BN, Balaji G, Alhajiri A, et al. Incremental diagnostic and prognostic value of contemporary stress echocardiography in a chest pain unit: mortality and morbidity outcomes from a real-world setting. Circ Cardiovasc Imaging. 2013;6(2):202-9. DOI:10.1161/CIRCIMAGING.112.980797
21. Gaibazzi N, Reverberi C, Badano L. Usefulness of contrast stress-echocardiography or exercise-electrocardiography to predict long-term acute coronary syndromes in patients presenting with chest pain without electrocardiographic abnormalities or 12-hour troponin elevation. Am J Cardiol. 2011;107(2):161-7. DOI:10.1016/j.amjcard.2010.08.066
22. Linde JJ, Kelbek H, Hansen TF, et al. Coronary CT Angiography in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome. J Am Coll Cardiol. 2020;75(5):453-63. DOI:10.1016/j.jacc.2019.12.012
23. Mehta SR, Granger CB, Boden WE, et al. Early versus delayed invasive intervention in acute coronary syndromes. N Engl J Med. 2009;360(21):2165-75. DOI:10.1056/NEJMoa0807986
24. Desperak P, Hawranek M, Gąsior P, et al. Long-term outcomes of patients with multivessel coronary artery disease presenting non-ST-segment elevation acute coronary syndromes. Cardiol J. 2019;26(2):157-68. DOI:10.5603/CJ.a2017.0110
25. Garcia S, Sandoval Y, Roukoz H, et al. Outcomes after complete versus incomplete revascularization of patients with multivessel coronary artery disease: a meta-analysis of 89,883 patients enrolled in randomized clinical trials and observational studies. J Am Coll Cardiol. 2013;62(16):1421-31. DOI:10.1016/j.jacc.2013.05.033
26. Généreux P, Palmerini T, Caixeta A, et al. Quantification and impact of untreated coronary artery disease after percutaneous coronary intervention: the residual SYNTAX (Synergy Between PCI with Taxus and Cardiac Surgery) score. J Am Coll Cardiol. 2012;59(24):2165-74. DOI:10.1016/j.jacc.2012.03.010
27. Farmer D, Jimenez E. Re-evaluating the Role of CABG in Acute Coronary Syndromes. Curr Cardiol Rep. 2020;22(11):148. DOI:10.1007/s11886-020-01386-y
28. Ramanathan K, Abel JG, Park JE, et al. Surgical Versus Percutaneous Coronary Revascularization in Patients With Diabetes and Acute Coronary Syndromes. J Am Coll Cardiol. 2017;70(24):2995-3006. DOI:10.1016/j.jacc.2017.10.029
29. Benedetto U, Sinha S, Mulla A, et al. Implications of elevated troponin on time-to-surgery in non-ST elevation myocardial infarction (NIHR Health Informatics Collaborative: TROP-CABG study). Int J Cardiol. 2022;362:14-9. DOI:10.1016/j.ijcard.2022.04.067
30. Jang JS, Jin HY, Seo JS, et al. Meta-analysis of multivessel versus culprit-only percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndrome and multivessel coronary disease. Am J Cardiol. 2015;115(8):1027-32. DOI:10.1016/j.amjcard.2015.01.530
31. Gazes PC, Mobley Jr. EM, Faris Jr. HM, et al. Preinfarctional (unstable) angina – a prospective study – ten year follow-up. Prognostic significance of electrocardiographic changes. Circulation. 1973;48(2):331-7. DOI:10.1161/01.CIR.48.2.331
32. Cairns JA, Gent M, Singer J, et al. Aspirin, sulfinpyrazone, or both in unstable angina. Results of a Canadian multicenter trial. N Engl J Med. 1985;313(22):1369-75. DOI:10.1056/NEJM198511283132201
33. Mulcahy R, Conroy R, Katz R, Fitzpatrick M. Does intensive medical therapy influence the outcome in unstable angina? Clin Cardiol. 1990;13(10):687-9. DOI:10.1002/clc.4960131003
34. Valentín V. Clopidogrel in acute coronary syndromes with non-ST elevation. Clinical implications of the CURE trial. Rev Esp Cardiol. 2001;54(10):1127-34 (in Spanish).
35. Baigent C, Blackwell L, Emberson J, et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet. 2010;376(9753):1670-81. DOI:10.1016/S0140-6736(10)61350-5
36. Erlikh AD. Twelve months outcomes in patients with acute coronary syndrome, by the national registry RECORD-3. Russian Journal of Cardiology. 2018;3:23-30 (in Russian. DOI:10.15829/1560-4071-2018-3-23-30
37. Shchinova AM, Potekhina AV, Dolgusheva YuA, et al. Comparison of in-hospital and long-term mortality and assessment of their predictors in patients with myocardial infarction and unstable angina. Almanac of Clinical Medicine. 2023;51(2):77-85 (in Russian). DOI:10.18786/2072-0505-2023-51-013
38. Roos A, Edgren G, Holzmann MJ. Unstable Angina Pectoris With Myocardial Injury Versus Myocardial Infarction in the Era of High-Sensitivity Cardiac Troponin. Am J Cardiol. 2022;169:32-41. DOI:10.1016/j.amjcard.2021.12.044
39. Katus HA, Giannitsis E. Prognostic Value of Serum Troponin T in Unstable Angina. Clin Chem. 2018;64(2):396-7. DOI:10.1373/clinchem.2017.272799
40. Sasaki S, Inoue K, Shiozaki M, et al. One-Year Outcome of Patients with Chest Pain in the Rule-Out Group According to the 0-Hour/1-Hour Algorithm. Int Heart J. 2023;64(4):590-5. DOI:10.1536/ihj.23-076
41. Shchinova AM, Potekhina AV, Dolgusheva YuA, et al. Comparison of the effectiveness of secondary prevention and long-term mortality after acute coronary syndrome depending on the form of follow-up. Russian Journal of Cardiology. 2023;28(7S):9-10 (in Russian). DOI:10.15829/1560-4071-2023-7S
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Авторы
С.А. Бойцов1,2, С.И. Проваторов*1
1ФГБУ «Национальный медицинский исследовательский центр кардиологии им. акад. Е.И. Чазова» Минздрава России, Москва, Россия;
2ФГБОУ ВО «Российский университет медицины» Минздрава России, Москва, Россия
*semaver@yandex.ru
1Chazov National Medical Research Center of Cardiology, Moscow, Russia;
2Russian University of Medicine, Moscow, Russia
*semaver@yandex.ru
1ФГБУ «Национальный медицинский исследовательский центр кардиологии им. акад. Е.И. Чазова» Минздрава России, Москва, Россия;
2ФГБОУ ВО «Российский университет медицины» Минздрава России, Москва, Россия
*semaver@yandex.ru
________________________________________________
1Chazov National Medical Research Center of Cardiology, Moscow, Russia;
2Russian University of Medicine, Moscow, Russia
*semaver@yandex.ru
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