Российский междисциплинарный консенсус по диагностике и лечению спондилоартритов при воспалительных заболеваниях кишечника - Журнал Терапевтический архив №2 Вопросы гастроэнтерологии 2025

Российский междисциплинарный консенсус по диагностике и лечению спондилоартритов при воспалительных заболеваниях кишечника

Лукина Г.В., Князев О.В., Белоусова Е.А., Абдулганиева Д.И., Александрова Е.Н., Бакулин И.Г., Барышева О.Ю., Борисова М.А., Выкова Б.А., Годзенко А.А., Губонина И.В., Дубинина Т.В., Жигалова Т.Н., Жиляев Е.В., Каграманова А.В., Коротаева Т.В., Кузин А.В., Ливзан М.А., Лила А.М., Мазуров В.И., Насонов Е.Л., Новиков А.А., Осипенко М.Ф., Парфенов А.И., Тарасова Л.В., Хлынова О.В., Шапина М.В., Щукина О.Б., Эрдес Ш.Ф., Яковлев А.А. Российский междисциплинарный консенсус по диагностике и лечению спондилоартритов при воспалительных заболеваниях кишечника. Терапевтический архив. 2025;97(2):198–213. DOI: 10.26442/00403660.2025.02.203117

© ООО «КОНСИЛИУМ МЕДИКУМ», 2025 г.

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Lukina GV, Knyazev OV, Belousova EA, Abdulganieva DI, Aleksandrova EN, Bakulin IG, Barysheva OIu, Borisova MА, Vykova BА, Godzenko AА, Gubonina IV, Dubinina TV, Zhigalova TN, Zhilyaev EV, Kagramanova AV, Korotaeva TV, Kuzin AV, Livzan MA, Lila AM, Mazurov VI, Nasonov EL, Novikov AA, Osipenko MF, Parfenov AI, Tarasova LV, Khlynova OV, Shapina MV, Shchukina OB, Erdes ShF, Iakovlev AA. Russian Cross-disciplinary Consensus on the diagnosis and treatment of spondyloarthritis associated with inflammatory bowel diseases. Terapevticheskii Arkhiv (Ter. Arkh.). 2025;97(2):198–213. DOI: 10.26442/00403660.2025.02.203117

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Аннотация

Российский междисциплинарный консенсус по диагностике и лечению спондилоартритов (СпА) при воспалительных заболеваниях кишечника (ВЗК) подготовлен по инициативе ГБУЗ «МКНЦ им. А.С. Логинова» по Дельфийской системе. Его целью явилась консолидация мнений отечественных специалистов по наиболее актуальным вопросам диагностики и лечения сочетанных иммуновоспалительных заболеваний (СпА и ВЗК). Междисциплинарный подход обеспечен участием ведущих гастроэнтерологов и ревматологов. Рабочей группой проанализированы отечественные и иностранные публикации, посвященные проблеме курации пациентов со СпА и ВЗК. Сформулировано 17 положений и 2 алгоритма лечения. Положения 1–3 отражают основополагающие принципы ведéния пациентов со СпА и ВЗК. Далее изложены принципы ранней диагностики СпА и ВЗК, в том числе и диагностики осложнений терапии. Одиннадцать положений посвящены современным методам лечения пациентов, на основании которых разработаны 2 алгоритма лечения. Положения консенсуса были представлены на рассмотрение экспертного совета, внесены правки, после чего состоялось онлайн-голосование. В данной работе представлены актуальные рекомендации по ведéнию, диагностике и лечению пациентов со СпА и ВЗК.

Ключевые слова: консенсус, воспалительные заболевания кишечника, спондилоартрит, лечение, диагностика

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The Russian Cross-disciplinary Consensus on the diagnositic and treatment of spondyloarthritis (SpA) in inflammatory bowel diseases (IBD) was prepared on the initiative of the Loginov Moscow Clinical Scientific Center, using the Delphic system. Its purpose was to consolidate the opinions of experts on the most actual issues of diagnosis and treatment of concomitant immuno-inflammatory diseases (SpA and IBD). An interdisciplinary approach is provided by the participation of leading gastroenterologists and rheumatologists. The working group analyzed domestic and foreign publications on the problem of curation of patients with SpA and IBD. There have been 17 statements and 2 treatment algorithms formulated. Statements 1–3 reflect the fundamental principles of management of patients with SpA and IBD. The principles of early diagnosis of SpA and IBD, including the diagnosis of complications of therapy, are described below. Eleven statements are devoted to current methods of treatment, on the basis of which 2 treatment algorithms have been developed. The statements of the Consensus were submitted to the Expert Council for consideration, edits were made, after which an online vote took place. This paper presents current recommendations for the management, diagnosis and treatment of patients with SpA and IBD.

Keywords: consensus, inflammatory bowel diseases, spondyloartritis, treatment, diagnostics

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Авторы

Г.В. Лукина^1,2, О.В. Князев*¹, Е.А. Белоусова³, Д.И. Абдулганиева⁴, Е.Н. Александрова¹, И.Г. Бакулин⁵, О.Ю. Барышева⁶, М.А. Борисова¹, Б.А. Выкова⁷, А.А. Годзенко⁸, И.В. Губонина⁹, Т.В. Дубинина², Т.Н. Жигалова¹⁰, Е.В. Жиляев^8,11,12, А.В. Каграманова¹, Т.В. Коротаева², А.В. Кузин⁸, М.А. Ливзан¹³, А.М. Лила², В.И. Мазуров¹⁴, Е.Л. Насонов², А.А. Новиков^1,12, М.Ф. Осипенко¹⁵, А.И. Парфенов¹, Л.В. Тарасова^16,17, О.В. Хлынова¹⁸, М.В. Шапина⁷, О.Б. Щукина¹⁹, Ш.Ф. Эрдес², А.А. Яковлев²⁰

¹ГБУЗ «Московский клинический научно-практический центр им. А.С. Логинова» Департамента здравоохранения г. Москвы, Москва, Россия;
²ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой», Москва, Россия;
³ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского», Москва, Россия;
⁴Министерство здравоохранения Республики Татарстан, Казань, Россия;
⁵ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова» Минздрава России, Санкт-Петербург, Россия;
⁶ГБУЗ РК «Республиканская больница им. В.А. Баранова», Петрозаводск, Россия;
⁷ФГБУ «Национальный медицинский исследовательский центр колопроктологии им. А.Н. Рыжих» Минздрава России, Москва, Россия;
⁸ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, Москва, Россия;
⁹Многопрофильная клиника «Скандинавия» (ООО «АВА-ПЕТЕР»), Санкт-Петербург, Россия;
¹⁰ГУЗ «Городская клиническая больница №31», Санкт-Петербург, Россия;
¹¹АО «Европейский медицинский центр», Москва, Россия;
¹²ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России (Пироговский Университет), Москва, Россия;
¹³ФГБОУ ВО «Омский государственный медицинский университет» Минздрава России, Омск, Россия;
¹⁴ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова» Минздрава России, Санкт-Петербург, Россия;
¹⁵ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России, Новосибирск, Россия;
¹⁶ФГБОУ ВО «Чувашский государственный университет им. И.Н. Ульянова», Чебоксары, Россия;
¹⁷БУ ЧР «Республиканская клиническая больница» Минздрава Чувашской Республики, Чебоксары, Россия;
¹⁸ФГБОУ ВО «Пермский государственный медицинский университет им. акад. Е.А. Вагнера» Минздрава России, Пермь, Россия;
¹⁹ФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова» Минздрава России, Санкт-Петербург, Россия;
²⁰ФГБОУ ВО «Ростовский государственный медицинский университет» Минздрава России, Ростов-на-Дону, Россия
*oleg7@bk.ru

________________________________________________

Galina V. Lukina^1,2, Oleg V. Knyazev*¹, Elena A. Belousova³, Diana I. Abdulganieva⁴, Elena N. Aleksandrova¹, Igor G. Bakulin⁵, Olga Iu. Barysheva⁶, Maria А. Borisova¹, Bella А. Vykova⁷, Alla А. Godzenko⁸, Irina V. Gubonina⁹, Tatiana V. Dubinina², Tatiana N. Zhigalova¹⁰, Evgeny V. Zhilyaev^8,11,12, Anna V. Kagramanova¹, Tatiana V. Korotaeva², Alexander V. Kuzin⁸, Maria A. Livzan¹³, Aleksander M. Lila², Vadim I. Mazurov¹⁴, Evgeny L. Nasonov², Alexander A. Novikov^1,12, Marina F. Osipenko¹⁵, Asfold I. Parfenov¹, Larisa V. Tarasova^16,17, Olga V. Khlynova¹⁸, Marina V. Shapina⁷, Oksana B. Shchukina¹⁹, Shandor F. Erdes², Aleksei A. Iakovlev²⁰

¹Loginov Moscow Clinical Scientific Center, Moscow, Russia;
²Nasonova Research Institute of Rheumatology, Moscow, Russia;
³Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia;
⁴Ministry of Health of the Republic of Tatarstan, Kazan, Russia;
⁵Mechnikov North-Western State Medical University, Saint Petersburg, Russia;
⁶Baranov Republican Hospital, Petrozavodsk, Russia;
⁷Ryzikh National Medical Research Centre for Coloproctology, Moscow, Russia;
⁸Russian Medical Academy of Continuous Professional Education, Moscow, Russia;
⁹Scandinavia Multidisciplinary Clinic (AVA-PETER LLC), Saint Petersburg, Russia;
¹⁰City Clinical Hospital No. 31, Saint Petersburg, Russia;
¹¹European Medical Center JSC, Moscow, Russia;
¹²Pirogov Russian National Research Medical University (Pirogov University), Moscow, Russia;
¹³Omsk State Medical University, Omsk, Russia;
¹⁴Mechnikov North-Western State Medical University, Saint Petersburg, Russia;
¹⁵Novosibirsk State Medical University, Novosibirsk, Russia;
¹⁶Ulyanov Chuvash State University, Cheboksary, Russia;
¹⁷Republican Clinical Hospital, Cheboksary, Russia;
¹⁸Academician Vagner Perm State Medical University, Perm, Russia;
¹⁹Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia;
²⁰Rostov State Medical University, Rostov-on-Don, Russia
*oleg7@bk.ru

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