Высоковариабельная и непредсказуемая природа эндокринных изменений во время репродуктивного старения женщин, особенно в период перехода к менопаузе, когда ряд соответствующих клинических симптомов свидетельствует о приближении к менопаузе и приносит неприятные беспокойства женщине, привлекает интересы как клиницистов, так и исследователей.
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