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Перспективы терапии ринитов и риносинуситов: обзор применения препарата Эуфорбиум композитум
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Marianovskii A.A. Prospects for treatment of rhinitis and rhinosinusitis: a review of the drug Euphorbium compositum. Consilium Medicum. 2016; 18 (3): 104–106. DOI: 10.26442/2075-1753_2016.3.104-106
Материалы доступны только для специалистов сферы здравоохранения. Авторизуйтесь или зарегистрируйтесь.
Ключевые слова: ринит, синусит, натуральные компоненты, спрей.
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Key words: rhinitis, sinusitis, natural ingredients, spray.
2. Zenner S, Metelmann H. Therapeutic Experiences with a Homeopathic Nasal Spray. Hufeland Journal 1992;3:67–74.
3. Gottwald R, Weiser M. Antihomotoxic treatment of chronic sinusitis: results of a drug monitoring study with Euphorbium compositum S Drops. Translated from Medicina Biológica 2000; 13 (3): 84–7.
4. Sprenger F. A study with Euphorbium compositum nasal drops (metered dose spray without propellant gas). J General Practice 1984; 60 (27): 1164–8.
5. Connert WD, Maiwald J. Therapie chronisch-medikamentös und vasormotorisch bedingter rhinopathien. Erfahrungen mit einem biotherapeutischen nasenspray. Therapiewoche 1987; 37: 1179–86. English translation available in: Connert WD, Maiwald J. The therapy of rhinopathy: results of application of a biotherapeutic nasal spray. Biol Therapy 1991; 9 (4): 182–92.
6. Weiser M, Gottwald R. Homöopathische Nasentropfen lassen bei Kindern Rhinitis und Sinusitis schneller abklingen. Therapeutische Mitteilungen. Gesundes Leben 1999; 6: 63.
7. Ammerschläger H, Klein P, Weiser M, Oberbaum M. Treatment of infl ammatory diseases of the upper respiratory tract – comparison of a homeopathic complex remedy with xylometazoline. Forsch Komplementärmed Klass Naturheilkd 2005; 12: 24–31.
8. Urlea-Schön MI. Effectiveness and tolerability of Euphorbium comp SN for the symptomatic treatment of rhinitis in children aged 2–6 years. Eur J Int Med 2009; 1: 236 (Abstract PO-023).
9. Raab V. Practice report. Further therapeutic experience with Euphorbium compositum nasal drops (metered dose spray without propellant gas) in ENT practice. Biologische Medizin 1982; 4: 176–9.
10. Glatthaar-Saalmüller B, Fallier-Becker P. Antiviral action of Euphorbium compositum and its components. Forsch Komplementärmed Klass Naturheilkd 2001; 4: 207–12.
11. Glatthaar-Saalmüller B et al. Euphorbium compositum: viruses of the upper respiratory tract inhibited. Biologische Medizin 2002; 4: 194–5.
12. Metelmann H, Glatthaar-Saalmüller B. Antiviral action of a homeopathic medication. Biomed Ther 2000; 18 (1): 160–4.
13. Schmolz M, Metelmann H. Modulation of cytokine synthesis in human leukocytes by individual components of a combination homeopathic nasal spray. Biol Therapy 1999; 17 (2): 61–3; 75.
14. Dykewicz MS, Hamilos DL. Rhinitis and sinusitis. J Allergy Clin Immunol 2010; 125 (2; Suppl. 2): S103–15.
15. Fokkens WJ, Lund VJ, Mullol J et al. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. Rhinology 2012; 50 (Suppl. 23): 1–298.
16. Wallace DV, Dykewicz MS, Bernstein DI et al. Joint Task Force on Practice; American Academy of Allergy; Asthma & Immunology; American College of Allergy; Asthma and Immunology; Joint Council of Allergy, Asthma and Immunology. The diagnosis and management of rhinitis: an updated practice parameter. J Allergy Clin Immunol 2008; 122 (2; Suppl): S1–84.
17. Rosenfeld RM, Andes D, Bhattacharyya N et al. Clinical practice guideline: adult sinusitis. Otolaryngol Head Neck Surg 2007; 137 (3; Suppl.): S1–31.
18. Settipane RA, Charnock DR. Epidemiology of rhinitis: allergic and nonallergic. Clin Allergy Immunol 2007; 19: 23–34.
19. Hamilos DL. Chronic rhinosinusitis patterns of illness. Clin Allergy Immunol 2007; 20: 1–13.
20. Mattos JL, Woodard CR, Payne SC. Trends in common rhinologic illnesses: analysis of U.S. healthcare surveys 1995–2007. Int Forum Allergy Rhinol 2011; 1 (1): 3–12.
21. Punekar YS, Sheikh A. Establishing the incidence and prevalence of clinician-diagnosed allergic conditions in children and adolescents using routinely collected data from general practices. Clin Exp Allergy 2009; 39 (8): 1209–16.
22. Ghouri N, Hippisley-Cox J, Newton J, Sheikh A. Trends in the epidemiology and prescribing of medication for allergic rhinitis in England. J R Soc Med 2008; 101 (9): 466–72.
23. Klossek JM, Annesi-Maesano I, Pribil C, Didier A. [INSTANT: national survey of allergic rhinitis in a French adult population based-sample]. Presse Med 2009; 38 (9): 1220–9.
24. Quercia O, Incorvaia C, Puccinelli P et al. Prevalence of allergic disorders in Italy: the Cotignola population study. Eur Ann Allergy Clin Immunol 2012; 44 (1): 5–11.
25. Bhattacharyya N. Functional limitations and workdays lost associated with chronic rhinosinusitis and allergic rhinitis. Am J Rhinol Allergy 2012; 26 (2): 120–2.
26. Hastan D, Fokkens WJ, Bachert C et al. Chronic rhinosinusitis in Europe – an underestimated disease. A GA(2)LEN study. Allergy 2011; 66 (9): 1216–23.
27. Jarvis D, Newson R, Lotvall J et al. Asthma in adults and its association with chronic rhinosinusitis: the GA(2)LEN survey in Europe. Allergy 2012; 67 (1): 91–8.
28. Skoner DP. Complications of allergic rhinitis. J Allergy Clin Immunol 2000; 105 (6; Pt 2): S605–609.
29. Cruz AA, Popov T, Pawankar R et al. ARIA Initiative Scientifi c Committee. Common characteristics of upper and lower airways in rhinitis and asthma: ARIA update, in collaboration with GA(2)LEN. Allergy 2007; 62 (Suppl. 84): 1–41.
30. De Groot EP, Nijkamp A, Duiverman EJ, Brand PL. Allergic rhinitis is associated with poor asthma control in children with asthma. Thorax 2012; Jan 2. [Epub ahead of print]
31. Dixon AE. Rhinosinusitis and asthma: the missing link. Curr Opin Pulm Med 2009; 15 (1): 19–24.
32. Lunn M, Craig T. Rhinitis and sleep. Sleep Med Rev 2011; 15 (5): 293–9.
33. Meltzer EO, Nathan R, Derebery J et al. Sleep, quality of life, and productivity impact of nasal symptoms in the United States: findings from the Burden of Rhinitis in America survey. Allergy Asthma Proc 2009; 30 (3): 244–54.
34. Craig TJ, Ferguson BJ, Krouse JH. Sleep impairment in allergic rhinitis, rhinosinusitis, and nasal polyposis. Am J Otolaryngol 2008; 29 (3): 209–17.
35. Hartgerink-Lutgens I, Vermeeren A, Vuurman E, Kremer B. Disturbed cognitive functions after nasal provocation in patients with seasonal allergic rhinitis. Clin Exp Allergy 2009; 39 (4): 500–8.
36. Meltzer EO, Gross GN, Katial R, Storms WW. Allergic rhinitis substantially impacts patient quality of life: fi ndings from the Nasal Allergy Survey Assessing Limitations. J Fam Pract 2012; 61 (2; Suppl.): S5–10.
37. Nathan RA. The burden of allergic rhinitis. Allergy Asthma Proc 2007; 28 (1): 3–9.
38. Blaiss MS. Pediatric allergic rhinitis: physical and mental complications. Allergy Asthma Proc 2008; 29 (1): 1–6.
39. Vuurman EF, van Veggel LM, Uiterwijk MM et al. Seasonal allergic rhinitis and antihistamine effects on children’s learning. Ann Allergy 1993; 71 (2): 121–6.
40. Willsie SK. Improved strategies and new treatment options for allergic rhinitis. J Am Osteopath Assoc 2002; 102 (6; Suppl. 2): S7–14.
41. Puchelle E, Zahm JM, Tournier JM, Coraux C. Airway epithelial repair, regeneration, and remodeling after injury in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006; 3 (8): 726–33.
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1. Weiser M, Clasen BPE. Randomized placebo controlled double-blind study of the clinical efficacy of the homeopathic Euphorbium compositum S-Nasal Spray in cases of chronic sinusitis. Forsch Komplementärmed Klass Naturheilkd 1994; 1: 251–9. English translation in: Biol Therapy 1995; 1: 4–11.
2. Zenner S, Metelmann H. Therapeutic Experiences with a Homeopathic Nasal Spray. Hufeland Journal 1992;3:67–74.
3. Gottwald R, Weiser M. Antihomotoxic treatment of chronic sinusitis: results of a drug monitoring study with Euphorbium compositum S Drops. Translated from Medicina Biológica 2000; 13 (3): 84–7.
4. Sprenger F. A study with Euphorbium compositum nasal drops (metered dose spray without propellant gas). J General Practice 1984; 60 (27): 1164–8.
5. Connert WD, Maiwald J. Therapie chronisch-medikamentös und vasormotorisch bedingter rhinopathien. Erfahrungen mit einem biotherapeutischen nasenspray. Therapiewoche 1987; 37: 1179–86. English translation available in: Connert WD, Maiwald J. The therapy of rhinopathy: results of application of a biotherapeutic nasal spray. Biol Therapy 1991; 9 (4): 182–92.
6. Weiser M, Gottwald R. Homöopathische Nasentropfen lassen bei Kindern Rhinitis und Sinusitis schneller abklingen. Therapeutische Mitteilungen. Gesundes Leben 1999; 6: 63.
7. Ammerschläger H, Klein P, Weiser M, Oberbaum M. Treatment of infl ammatory diseases of the upper respiratory tract – comparison of a homeopathic complex remedy with xylometazoline. Forsch Komplementärmed Klass Naturheilkd 2005; 12: 24–31.
8. Urlea-Schön MI. Effectiveness and tolerability of Euphorbium comp SN for the symptomatic treatment of rhinitis in children aged 2–6 years. Eur J Int Med 2009; 1: 236 (Abstract PO-023).
9. Raab V. Practice report. Further therapeutic experience with Euphorbium compositum nasal drops (metered dose spray without propellant gas) in ENT practice. Biologische Medizin 1982; 4: 176–9.
10. Glatthaar-Saalmüller B, Fallier-Becker P. Antiviral action of Euphorbium compositum and its components. Forsch Komplementärmed Klass Naturheilkd 2001; 4: 207–12.
11. Glatthaar-Saalmüller B et al. Euphorbium compositum: viruses of the upper respiratory tract inhibited. Biologische Medizin 2002; 4: 194–5.
12. Metelmann H, Glatthaar-Saalmüller B. Antiviral action of a homeopathic medication. Biomed Ther 2000; 18 (1): 160–4.
13. Schmolz M, Metelmann H. Modulation of cytokine synthesis in human leukocytes by individual components of a combination homeopathic nasal spray. Biol Therapy 1999; 17 (2): 61–3; 75.
14. Dykewicz MS, Hamilos DL. Rhinitis and sinusitis. J Allergy Clin Immunol 2010; 125 (2; Suppl. 2): S103–15.
15. Fokkens WJ, Lund VJ, Mullol J et al. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. Rhinology 2012; 50 (Suppl. 23): 1–298.
16. Wallace DV, Dykewicz MS, Bernstein DI et al. Joint Task Force on Practice; American Academy of Allergy; Asthma & Immunology; American College of Allergy; Asthma and Immunology; Joint Council of Allergy, Asthma and Immunology. The diagnosis and management of rhinitis: an updated practice parameter. J Allergy Clin Immunol 2008; 122 (2; Suppl): S1–84.
17. Rosenfeld RM, Andes D, Bhattacharyya N et al. Clinical practice guideline: adult sinusitis. Otolaryngol Head Neck Surg 2007; 137 (3; Suppl.): S1–31.
18. Settipane RA, Charnock DR. Epidemiology of rhinitis: allergic and nonallergic. Clin Allergy Immunol 2007; 19: 23–34.
19. Hamilos DL. Chronic rhinosinusitis patterns of illness. Clin Allergy Immunol 2007; 20: 1–13.
20. Mattos JL, Woodard CR, Payne SC. Trends in common rhinologic illnesses: analysis of U.S. healthcare surveys 1995–2007. Int Forum Allergy Rhinol 2011; 1 (1): 3–12.
21. Punekar YS, Sheikh A. Establishing the incidence and prevalence of clinician-diagnosed allergic conditions in children and adolescents using routinely collected data from general practices. Clin Exp Allergy 2009; 39 (8): 1209–16.
22. Ghouri N, Hippisley-Cox J, Newton J, Sheikh A. Trends in the epidemiology and prescribing of medication for allergic rhinitis in England. J R Soc Med 2008; 101 (9): 466–72.
23. Klossek JM, Annesi-Maesano I, Pribil C, Didier A. [INSTANT: national survey of allergic rhinitis in a French adult population based-sample]. Presse Med 2009; 38 (9): 1220–9.
24. Quercia O, Incorvaia C, Puccinelli P et al. Prevalence of allergic disorders in Italy: the Cotignola population study. Eur Ann Allergy Clin Immunol 2012; 44 (1): 5–11.
25. Bhattacharyya N. Functional limitations and workdays lost associated with chronic rhinosinusitis and allergic rhinitis. Am J Rhinol Allergy 2012; 26 (2): 120–2.
26. Hastan D, Fokkens WJ, Bachert C et al. Chronic rhinosinusitis in Europe – an underestimated disease. A GA(2)LEN study. Allergy 2011; 66 (9): 1216–23.
27. Jarvis D, Newson R, Lotvall J et al. Asthma in adults and its association with chronic rhinosinusitis: the GA(2)LEN survey in Europe. Allergy 2012; 67 (1): 91–8.
28. Skoner DP. Complications of allergic rhinitis. J Allergy Clin Immunol 2000; 105 (6; Pt 2): S605–609.
29. Cruz AA, Popov T, Pawankar R et al. ARIA Initiative Scientifi c Committee. Common characteristics of upper and lower airways in rhinitis and asthma: ARIA update, in collaboration with GA(2)LEN. Allergy 2007; 62 (Suppl. 84): 1–41.
30. De Groot EP, Nijkamp A, Duiverman EJ, Brand PL. Allergic rhinitis is associated with poor asthma control in children with asthma. Thorax 2012; Jan 2. [Epub ahead of print]
31. Dixon AE. Rhinosinusitis and asthma: the missing link. Curr Opin Pulm Med 2009; 15 (1): 19–24.
32. Lunn M, Craig T. Rhinitis and sleep. Sleep Med Rev 2011; 15 (5): 293–9.
33. Meltzer EO, Nathan R, Derebery J et al. Sleep, quality of life, and productivity impact of nasal symptoms in the United States: findings from the Burden of Rhinitis in America survey. Allergy Asthma Proc 2009; 30 (3): 244–54.
34. Craig TJ, Ferguson BJ, Krouse JH. Sleep impairment in allergic rhinitis, rhinosinusitis, and nasal polyposis. Am J Otolaryngol 2008; 29 (3): 209–17.
35. Hartgerink-Lutgens I, Vermeeren A, Vuurman E, Kremer B. Disturbed cognitive functions after nasal provocation in patients with seasonal allergic rhinitis. Clin Exp Allergy 2009; 39 (4): 500–8.
36. Meltzer EO, Gross GN, Katial R, Storms WW. Allergic rhinitis substantially impacts patient quality of life: fi ndings from the Nasal Allergy Survey Assessing Limitations. J Fam Pract 2012; 61 (2; Suppl.): S5–10.
37. Nathan RA. The burden of allergic rhinitis. Allergy Asthma Proc 2007; 28 (1): 3–9.
38. Blaiss MS. Pediatric allergic rhinitis: physical and mental complications. Allergy Asthma Proc 2008; 29 (1): 1–6.
39. Vuurman EF, van Veggel LM, Uiterwijk MM et al. Seasonal allergic rhinitis and antihistamine effects on children’s learning. Ann Allergy 1993; 71 (2): 121–6.
40. Willsie SK. Improved strategies and new treatment options for allergic rhinitis. J Am Osteopath Assoc 2002; 102 (6; Suppl. 2): S7–14.
41. Puchelle E, Zahm JM, Tournier JM, Coraux C. Airway epithelial repair, regeneration, and remodeling after injury in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006; 3 (8): 726–33.
ГБОУ ВПО Российский национальный исследовательский медицинский университет им. Н.И.Пирогова Минздрава России. 117997, Россия, Москва, ул. Островитянова, д. 1
Marjanovsky@arnebia.ru
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N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation. 117997, Russian Federation, Moscow, ul. Ostrovitianova, d. 1
Marjanovsky@arnebia.ru