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Использование системной антибактериальной терапии при острых инфекциях верхних дыхательных путей и уха
Использование системной антибактериальной терапии при острых инфекциях верхних дыхательных путей и уха
Мальцева Г.С. Использование системной антибактериальной терапии при острых инфекциях верхних дыхательных путей и уха. Болезни органов дыхания (Прил. к журн. Consilium Medicum). 2018; с. 48–52. DOI: 10.26442/2619-0079.2018.48-52
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Аннотация
Подавляющее большинство острых респираторных инфекций имеет вирусную природу. Основными бактериальными патогенами, обусловливающими развитие острого синусита и острого среднего отита, являются Streptococcus pneumoniae, Haemophilus influenzae и Moraxella catarrhalis, в то время как острого фаринготонзиллита – Streptococcus pyogenes. В статье даны клинические признаки бактериальной инфекции околоносовых пазух, глотки и уха, показания к системной антибактериальной терапии. Рассмотрены вопросы выбора антибактериального препарата для лечения острого бактериального синусита, острого фаринготонзиллита и острого среднего отита, показано место цефалоспоринов III поколения в лечении указанной патологии. В статье приводится обзор данных клинических исследований эффективности и безопасности цефиксима при заболеваниях верхних дыхательных путей и уха.
Ключевые слова: острый средний отит, острый бактериальный синусит, острый фаринготонзиллит, антибиотикотерапия.
Key words: acute otitis media, acute bacterial sinusitis, acute pharyngotonsillitis, antibacterial therapy.
Ключевые слова: острый средний отит, острый бактериальный синусит, острый фаринготонзиллит, антибиотикотерапия.
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Key words: acute otitis media, acute bacterial sinusitis, acute pharyngotonsillitis, antibacterial therapy.
Полный текст
Список литературы
1. Harbarth S, Balkhy HH, Goossens H et al. Antimicrobial resistance: one world, one fight! Antimicrob Res Infect Control 2015; 4: 49.
2. McCullough AR, Pollack AJ, Plejdrup Hansen M et al. Antibiotics for acute respiratory infections in general practice: comparison of prescribing rates with guideline recommendations. Med J Aust 2017; 207: 65–9.
3. Fleming-Dutra KE, Hersh AL, Shapiro DJ et al. Prevalence of inappropriate antibiotic prescriptions among US ambulatory care visits, 2010–2011. JAMA 2016; 315: 1864–73.
4. Bjornsdottir I, Kristinsson KG, Hansen EH. Diagnosing infections: a qualitative view on prescription decisions in general practice over time. Pharm World Sci 2010; 32: 805–14.
5. Palmu AA, Herva E, Savolainen H et al. Association of clinical signs and symptoms with bacterial findings in acute otitis media. Clin Infect Dis 2004; 38: 234–42.
6. Lieberthal AS, Carroll AE, Chonmaitree T et al. The diagnosis and management of acute otitis media. Pediatrics 2013; 131: e964–99.
7. Rovers MM, Appelman GP, Burke CL et al. Antibiotics for acute otitis media: a metaanalysis with individual patient data. Lancet 2006; 368: 1429–35.
8. Козлов Р.С., Сивая О.В., Кречикова О.И. и др. Динамика резистентности Streptococcus pneomoniae к антибиотикам в России за период 1999–2009 гг. Клин. микробиол. и антимикроб. химиотер. 2010; 4: 1–13. / Kozlov R.S., Sivaia O.V., Krechikova O.I. i dr. Dinamika rezistentnosti Streptococcus pneomoniae k antibiotikam v Rossii za period 1999–2009 gg. Klin. mikrobiol. i antimikrob. khimioter. 2010; 4: 1–13. [in Russian]
9. Jacobs MR, Felmingham D, Appelbaum PC, Gruneberg RN, Alexander Project Group. The Alexander Project 1998–2000: susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents. J Antimicrob Chemother 2003; 52 (2): 229–46.
10. Harrison CJ, Woods C, Strout G, Martin B, Selvarangan R. Susceptibilities of Haemophilus influenza, Streptococcus pneumonia, including serotype 19A, and Moraxella catarrhalis peadiatric isolates from 2005 to 2007 to commonly used antibiotics. J Antimicrob Chemother 2009; 63 (3): 511–9.
11. Low DE, Desrosiers M, McSherry J et al. A practical guide for the diagnosis and treatment of acute sinusitis. CMAJ 1997; 156 (Suppl. 6): 1–14.
12. Farrell DJ, Klugman KP, Pichichero M. Increased antimicrobial resistance among nonvaccine serotypes of Streptococcus pneumoniae in the pediatric population after the introduction of 7-valent pneumococcal vaccine in the United States. Pediatr Infect Dis 2007; 26 (2): 123–8.
13. McLinn SE: Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion. Pediatr Infect Dis J 1987; 6: 997–1001.
14. Owen MJ, Anwar R, Nguyen HK et al. Efficacy of efixime in the treatment of acute otitis media in children. Am J Dis Child 1993; 147: 81–6.
15. Johnson CE, Carlin SA, Super DM et al. Cefixime compared with amoxicillin for treatment of acute otitis media. J Pediatr 1991; 119: 117–22.
16. Jansen WTM, Verel A, Beitsma M et al. Longitudinal European surveillance study of antibiotic resistance of Haemophilus influenza. J Antimicrob Chemother 2006; 58: 873–7.
17. Hausen Th, Weidlich G, Schmitt J. Safety and efficacy of cefixime in the treatment of respiratory tract infections in Germany. Infection 1995; 23 (Suppl. 2): 65–9.
18. DeMuri GP, Gern JE, Moyer SC et al. Clinical features, virus identification, and sinusitis as a complication of upper respiratory tract illness in children ages 4–7 years. J Pediatr 2016; 171: 133–9.
19. Hickner JM, Bartlett JG, Besser RE et al. Principles of appropriate antibiotic use for acute rhinosinusitis in adults: background. Ann Intern Med 2001; 134: 498–505.
20. Rosenfeld RM, Piccirillo JF, Chandrasekhar SS et al. Clinical practice guideline (update): adult sinusitis. Otolaryngol Head Neck Surg 2015; 152: S1–39.
21. Hansen FS, Hoffmans R, Georgalas C, Fokkens WJ. Complications of acute rhinosinusitis in The Netherlands. Fam Pract 2012; 29: 147–53.
22. Bastier PL, Lechot A, Bordenave L et al. Nasal irrigation: from empiricism to evidence-based medicine. A review. Eur Ann Otorhinolaryngol Head Neck Dis 2015; 132: 281–5.
23. Gehanno P, Boucot I, Berche P, Uhlrich J. Clinical efficacy and tolerability of cefixime in the treatment of acute sinusitis. Drugs 1991; 42 (Suppl. 4): 19–24.
24. Matthews BL, Kohut RI, Edelstein DR et al. Evaluation of cefixime in the treatment of bacterial maxillary sinusitis. South Med J 1993; 86 (3): 329–33.
25. Радциг Е.Ю., Пивнева Н.Д., Котова Е.Н. и др. Эффективность перорального цефалоспорина III поколения при ЛОР-патологии у детей. Лечащий врач. 2014; 10: 52. / Radtsig E.Iu., Pivneva N.D., Kotova E.N. i dr. Effektivnost' peroral'nogo tsefalosporina III pokoleniia pri LOR-patologii u deteĭ. Lechashchiĭ vrach. 2014; 10: 52 [in Russian]
26. Овчинников А.Ю., Овчаренко С.И., Колбанова И.Г. Влияние эффективного лечения бактериального риносинусита на течение сопутствующей бронхиальной астмы. Лечащий врач. 2007; 8: 9–13. / Ovchinnikov A.Iu., Ovcharenko S.I., Kolbanova I.G. Vliianie effektivnogo lecheniia bakterial'nogo rinosinusita na techenie soputstvuiushcheĭ bronkhial'noĭ astmy. Lechashchiĭ vrach. 2007; 8: 9–13. [in Russian]
27. Белов Б.С. Цефиксим в терапии бактериальных инфекций. РМЖ. 2013; 3. /
Belov B.S. Tsefiksim v terapii bakterial'nykh infektsiĭ. RMZh. 2013; 3. [in Russian]
28. Панякина М.А., Овчинников А.Ю., Мирошниченко Н.А. О целесообразности применения цефиксима для лечения больных острым бактериальным риносинуситом. Фарматека. 2013; 4. / Paniakina M.A., Ovchinnikov A.Iu., Miroshnichenko N.A. O tselesoobraznosti primeneniia tsefiksima dlia lecheniia bol'nykh ostrym bakterial'nym rinosinusitom. Farmateka. 2013; 4. [in Russian]
29. Weber R. Pharyngitis. Prim Care 2014; 41: 91–8.
30. Windfuhr JP, Toepfner N, Steffen G et al. Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management. Eur Arch Otorhinol 2016; 273: 973–87.
31. Petersen I, Johnson AM, Islam A et al. Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice Research Database. BMJ 2007; 335: 982.
32. Spinks A, Glasziou PP, Del Mar CB. Antibiotics for sore throat. Cochrane Database Syst Rev 2013. CD000023.
33. Gerber MA, Baltimore RS, Eaton CB et al. Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific state ment from the American Heart Association Rheumatic Fever. Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics. Circulation 2009; 119: 1541–51.
34. Егорова О.А., Козлов С.Н. Цефиксим в терапии инфекций ЛОР-органов у детей. Вопр. совр. педиатрии. 2008; 7 (3): 52–7. / Egorova O.A., Kozlov S.N. Tsefiksim v terapii infektsii LOR-organov u detei. Vopr. sovr. pediatrii. 2008; 7 (3): 52–7. [in Russian]
35. Casey J, Pichichero ME. Meta-analysis of cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis in children. Pediatrics 2004; 113 (4): 866–82.
2. McCullough AR, Pollack AJ, Plejdrup Hansen M et al. Antibiotics for acute respiratory infections in general practice: comparison of prescribing rates with guideline recommendations. Med J Aust 2017; 207: 65–9.
3. Fleming-Dutra KE, Hersh AL, Shapiro DJ et al. Prevalence of inappropriate antibiotic prescriptions among US ambulatory care visits, 2010–2011. JAMA 2016; 315: 1864–73.
4. Bjornsdottir I, Kristinsson KG, Hansen EH. Diagnosing infections: a qualitative view on prescription decisions in general practice over time. Pharm World Sci 2010; 32: 805–14.
5. Palmu AA, Herva E, Savolainen H et al. Association of clinical signs and symptoms with bacterial findings in acute otitis media. Clin Infect Dis 2004; 38: 234–42.
6. Lieberthal AS, Carroll AE, Chonmaitree T et al. The diagnosis and management of acute otitis media. Pediatrics 2013; 131: e964–99.
7. Rovers MM, Appelman GP, Burke CL et al. Antibiotics for acute otitis media: a metaanalysis with individual patient data. Lancet 2006; 368: 1429–35.
8. Kozlov R.S., Sivaia O.V., Krechikova O.I. i dr. Dinamika rezistentnosti Streptococcus pneomoniae k antibiotikam v Rossii za period 1999–2009 gg. Klin. mikrobiol. i antimikrob. khimioter. 2010; 4: 1–13. [in Russian]
9. Jacobs MR, Felmingham D, Appelbaum PC, Gruneberg RN, Alexander Project Group. The Alexander Project 1998–2000: susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents. J Antimicrob Chemother 2003; 52 (2): 229–46.
10. Harrison CJ, Woods C, Strout G, Martin B, Selvarangan R. Susceptibilities of Haemophilus influenza, Streptococcus pneumonia, including serotype 19A, and Moraxella catarrhalis peadiatric isolates from 2005 to 2007 to commonly used antibiotics. J Antimicrob Chemother 2009; 63 (3): 511–9.
11. Low DE, Desrosiers M, McSherry J et al. A practical guide for the diagnosis and treatment of acute sinusitis. CMAJ 1997; 156 (Suppl. 6): 1–14.
12. Farrell DJ, Klugman KP, Pichichero M. Increased antimicrobial resistance among nonvaccine serotypes of Streptococcus pneumoniae in the pediatric population after the introduction of 7-valent pneumococcal vaccine in the United States. Pediatr Infect Dis 2007; 26 (2): 123–8.
13. McLinn SE: Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion. Pediatr Infect Dis J 1987; 6: 997–1001.
14. Owen MJ, Anwar R, Nguyen HK et al. Efficacy of efixime in the treatment of acute otitis media in children. Am J Dis Child 1993; 147: 81–6.
15. Johnson CE, Carlin SA, Super DM et al. Cefixime compared with amoxicillin for treatment of acute otitis media. J Pediatr 1991; 119: 117–22.
16. Jansen WTM, Verel A, Beitsma M et al. Longitudinal European surveillance study of antibiotic resistance of Haemophilus influenza. J Antimicrob Chemother 2006; 58: 873–7.
17. Hausen Th, Weidlich G, Schmitt J. Safety and efficacy of cefixime in the treatment of respiratory tract infections in Germany. Infection 1995; 23 (Suppl. 2): 65–9.
18. DeMuri GP, Gern JE, Moyer SC et al. Clinical features, virus identification, and sinusitis as a complication of upper respiratory tract illness in children ages 4–7 years. J Pediatr 2016; 171: 133–9.
19. Hickner JM, Bartlett JG, Besser RE et al. Principles of appropriate antibiotic use for acute rhinosinusitis in adults: background. Ann Intern Med 2001; 134: 498–505.
20. Rosenfeld RM, Piccirillo JF, Chandrasekhar SS et al. Clinical practice guideline (update): adult sinusitis. Otolaryngol Head Neck Surg 2015; 152: S1–39.
21. Hansen FS, Hoffmans R, Georgalas C, Fokkens WJ. Complications of acute rhinosinusitis in The Netherlands. Fam Pract 2012; 29: 147–53.
22. Bastier PL, Lechot A, Bordenave L et al. Nasal irrigation: from empiricism to evidence-based medicine. A review. Eur Ann Otorhinolaryngol Head Neck Dis 2015; 132: 281–5.
23. Gehanno P, Boucot I, Berche P, Uhlrich J. Clinical efficacy and tolerability of cefixime in the treatment of acute sinusitis. Drugs 1991; 42 (Suppl. 4): 19–24.
24. Matthews BL, Kohut RI, Edelstein DR et al. Evaluation of cefixime in the treatment of bacterial maxillary sinusitis. South Med J 1993; 86 (3): 329–33.
25. Radtsig E.Iu., Pivneva N.D., Kotova E.N. i dr. Effektivnost' peroral'nogo tsefalosporina III pokoleniia pri LOR-patologii u deteĭ. Lechashchiĭ vrach. 2014; 10: 52 [in Russian]
26. Ovchinnikov A.Iu., Ovcharenko S.I., Kolbanova I.G. Vliianie effektivnogo lecheniia bakterial'nogo rinosinusita na techenie soputstvuiushcheĭ bronkhial'noĭ astmy. Lechashchiĭ vrach. 2007; 8: 9–13. [in Russian]
27. Belov B.S. Tsefiksim v terapii bakterial'nykh infektsiĭ. RMZh. 2013; 3. [in Russian]
28. Paniakina M.A., Ovchinnikov A.Iu., Miroshnichenko N.A. O tselesoobraznosti primeneniia tsefiksima dlia lecheniia bol'nykh ostrym bakterial'nym rinosinusitom. Farmateka. 2013; 4. [in Russian]
29. Weber R. Pharyngitis. Prim Care 2014; 41: 91–8.
30. Windfuhr JP, Toepfner N, Steffen G et al. Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management. Eur Arch Otorhinol 2016; 273: 973–87.
31. Petersen I, Johnson AM, Islam A et al. Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice Research Database. BMJ 2007; 335: 982.
32. Spinks A, Glasziou PP, Del Mar CB. Antibiotics for sore throat. Cochrane Database Syst Rev 2013. CD000023.
33. Gerber MA, Baltimore RS, Eaton CB et al. Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific state ment from the American Heart Association Rheumatic Fever. Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics. Circulation 2009; 119: 1541–51.
34. Egorova O.A., Kozlov S.N. Tsefiksim v terapii infektsii LOR-organov u detei. Vopr. sovr. pediatrii. 2008; 7 (3): 52–7. [in Russian]
35. Casey J, Pichichero ME. Meta-analysis of cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis in children. Pediatrics 2004; 113 (4): 866–82.
2. McCullough AR, Pollack AJ, Plejdrup Hansen M et al. Antibiotics for acute respiratory infections in general practice: comparison of prescribing rates with guideline recommendations. Med J Aust 2017; 207: 65–9.
3. Fleming-Dutra KE, Hersh AL, Shapiro DJ et al. Prevalence of inappropriate antibiotic prescriptions among US ambulatory care visits, 2010–2011. JAMA 2016; 315: 1864–73.
4. Bjornsdottir I, Kristinsson KG, Hansen EH. Diagnosing infections: a qualitative view on prescription decisions in general practice over time. Pharm World Sci 2010; 32: 805–14.
5. Palmu AA, Herva E, Savolainen H et al. Association of clinical signs and symptoms with bacterial findings in acute otitis media. Clin Infect Dis 2004; 38: 234–42.
6. Lieberthal AS, Carroll AE, Chonmaitree T et al. The diagnosis and management of acute otitis media. Pediatrics 2013; 131: e964–99.
7. Rovers MM, Appelman GP, Burke CL et al. Antibiotics for acute otitis media: a metaanalysis with individual patient data. Lancet 2006; 368: 1429–35.
8. Козлов Р.С., Сивая О.В., Кречикова О.И. и др. Динамика резистентности Streptococcus pneomoniae к антибиотикам в России за период 1999–2009 гг. Клин. микробиол. и антимикроб. химиотер. 2010; 4: 1–13. / Kozlov R.S., Sivaia O.V., Krechikova O.I. i dr. Dinamika rezistentnosti Streptococcus pneomoniae k antibiotikam v Rossii za period 1999–2009 gg. Klin. mikrobiol. i antimikrob. khimioter. 2010; 4: 1–13. [in Russian]
9. Jacobs MR, Felmingham D, Appelbaum PC, Gruneberg RN, Alexander Project Group. The Alexander Project 1998–2000: susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents. J Antimicrob Chemother 2003; 52 (2): 229–46.
10. Harrison CJ, Woods C, Strout G, Martin B, Selvarangan R. Susceptibilities of Haemophilus influenza, Streptococcus pneumonia, including serotype 19A, and Moraxella catarrhalis peadiatric isolates from 2005 to 2007 to commonly used antibiotics. J Antimicrob Chemother 2009; 63 (3): 511–9.
11. Low DE, Desrosiers M, McSherry J et al. A practical guide for the diagnosis and treatment of acute sinusitis. CMAJ 1997; 156 (Suppl. 6): 1–14.
12. Farrell DJ, Klugman KP, Pichichero M. Increased antimicrobial resistance among nonvaccine serotypes of Streptococcus pneumoniae in the pediatric population after the introduction of 7-valent pneumococcal vaccine in the United States. Pediatr Infect Dis 2007; 26 (2): 123–8.
13. McLinn SE: Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion. Pediatr Infect Dis J 1987; 6: 997–1001.
14. Owen MJ, Anwar R, Nguyen HK et al. Efficacy of efixime in the treatment of acute otitis media in children. Am J Dis Child 1993; 147: 81–6.
15. Johnson CE, Carlin SA, Super DM et al. Cefixime compared with amoxicillin for treatment of acute otitis media. J Pediatr 1991; 119: 117–22.
16. Jansen WTM, Verel A, Beitsma M et al. Longitudinal European surveillance study of antibiotic resistance of Haemophilus influenza. J Antimicrob Chemother 2006; 58: 873–7.
17. Hausen Th, Weidlich G, Schmitt J. Safety and efficacy of cefixime in the treatment of respiratory tract infections in Germany. Infection 1995; 23 (Suppl. 2): 65–9.
18. DeMuri GP, Gern JE, Moyer SC et al. Clinical features, virus identification, and sinusitis as a complication of upper respiratory tract illness in children ages 4–7 years. J Pediatr 2016; 171: 133–9.
19. Hickner JM, Bartlett JG, Besser RE et al. Principles of appropriate antibiotic use for acute rhinosinusitis in adults: background. Ann Intern Med 2001; 134: 498–505.
20. Rosenfeld RM, Piccirillo JF, Chandrasekhar SS et al. Clinical practice guideline (update): adult sinusitis. Otolaryngol Head Neck Surg 2015; 152: S1–39.
21. Hansen FS, Hoffmans R, Georgalas C, Fokkens WJ. Complications of acute rhinosinusitis in The Netherlands. Fam Pract 2012; 29: 147–53.
22. Bastier PL, Lechot A, Bordenave L et al. Nasal irrigation: from empiricism to evidence-based medicine. A review. Eur Ann Otorhinolaryngol Head Neck Dis 2015; 132: 281–5.
23. Gehanno P, Boucot I, Berche P, Uhlrich J. Clinical efficacy and tolerability of cefixime in the treatment of acute sinusitis. Drugs 1991; 42 (Suppl. 4): 19–24.
24. Matthews BL, Kohut RI, Edelstein DR et al. Evaluation of cefixime in the treatment of bacterial maxillary sinusitis. South Med J 1993; 86 (3): 329–33.
25. Радциг Е.Ю., Пивнева Н.Д., Котова Е.Н. и др. Эффективность перорального цефалоспорина III поколения при ЛОР-патологии у детей. Лечащий врач. 2014; 10: 52. / Radtsig E.Iu., Pivneva N.D., Kotova E.N. i dr. Effektivnost' peroral'nogo tsefalosporina III pokoleniia pri LOR-patologii u deteĭ. Lechashchiĭ vrach. 2014; 10: 52 [in Russian]
26. Овчинников А.Ю., Овчаренко С.И., Колбанова И.Г. Влияние эффективного лечения бактериального риносинусита на течение сопутствующей бронхиальной астмы. Лечащий врач. 2007; 8: 9–13. / Ovchinnikov A.Iu., Ovcharenko S.I., Kolbanova I.G. Vliianie effektivnogo lecheniia bakterial'nogo rinosinusita na techenie soputstvuiushcheĭ bronkhial'noĭ astmy. Lechashchiĭ vrach. 2007; 8: 9–13. [in Russian]
27. Белов Б.С. Цефиксим в терапии бактериальных инфекций. РМЖ. 2013; 3. /
Belov B.S. Tsefiksim v terapii bakterial'nykh infektsiĭ. RMZh. 2013; 3. [in Russian]
28. Панякина М.А., Овчинников А.Ю., Мирошниченко Н.А. О целесообразности применения цефиксима для лечения больных острым бактериальным риносинуситом. Фарматека. 2013; 4. / Paniakina M.A., Ovchinnikov A.Iu., Miroshnichenko N.A. O tselesoobraznosti primeneniia tsefiksima dlia lecheniia bol'nykh ostrym bakterial'nym rinosinusitom. Farmateka. 2013; 4. [in Russian]
29. Weber R. Pharyngitis. Prim Care 2014; 41: 91–8.
30. Windfuhr JP, Toepfner N, Steffen G et al. Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management. Eur Arch Otorhinol 2016; 273: 973–87.
31. Petersen I, Johnson AM, Islam A et al. Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice Research Database. BMJ 2007; 335: 982.
32. Spinks A, Glasziou PP, Del Mar CB. Antibiotics for sore throat. Cochrane Database Syst Rev 2013. CD000023.
33. Gerber MA, Baltimore RS, Eaton CB et al. Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific state ment from the American Heart Association Rheumatic Fever. Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics. Circulation 2009; 119: 1541–51.
34. Егорова О.А., Козлов С.Н. Цефиксим в терапии инфекций ЛОР-органов у детей. Вопр. совр. педиатрии. 2008; 7 (3): 52–7. / Egorova O.A., Kozlov S.N. Tsefiksim v terapii infektsii LOR-organov u detei. Vopr. sovr. pediatrii. 2008; 7 (3): 52–7. [in Russian]
35. Casey J, Pichichero ME. Meta-analysis of cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis in children. Pediatrics 2004; 113 (4): 866–82.
________________________________________________
2. McCullough AR, Pollack AJ, Plejdrup Hansen M et al. Antibiotics for acute respiratory infections in general practice: comparison of prescribing rates with guideline recommendations. Med J Aust 2017; 207: 65–9.
3. Fleming-Dutra KE, Hersh AL, Shapiro DJ et al. Prevalence of inappropriate antibiotic prescriptions among US ambulatory care visits, 2010–2011. JAMA 2016; 315: 1864–73.
4. Bjornsdottir I, Kristinsson KG, Hansen EH. Diagnosing infections: a qualitative view on prescription decisions in general practice over time. Pharm World Sci 2010; 32: 805–14.
5. Palmu AA, Herva E, Savolainen H et al. Association of clinical signs and symptoms with bacterial findings in acute otitis media. Clin Infect Dis 2004; 38: 234–42.
6. Lieberthal AS, Carroll AE, Chonmaitree T et al. The diagnosis and management of acute otitis media. Pediatrics 2013; 131: e964–99.
7. Rovers MM, Appelman GP, Burke CL et al. Antibiotics for acute otitis media: a metaanalysis with individual patient data. Lancet 2006; 368: 1429–35.
8. Kozlov R.S., Sivaia O.V., Krechikova O.I. i dr. Dinamika rezistentnosti Streptococcus pneomoniae k antibiotikam v Rossii za period 1999–2009 gg. Klin. mikrobiol. i antimikrob. khimioter. 2010; 4: 1–13. [in Russian]
9. Jacobs MR, Felmingham D, Appelbaum PC, Gruneberg RN, Alexander Project Group. The Alexander Project 1998–2000: susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents. J Antimicrob Chemother 2003; 52 (2): 229–46.
10. Harrison CJ, Woods C, Strout G, Martin B, Selvarangan R. Susceptibilities of Haemophilus influenza, Streptococcus pneumonia, including serotype 19A, and Moraxella catarrhalis peadiatric isolates from 2005 to 2007 to commonly used antibiotics. J Antimicrob Chemother 2009; 63 (3): 511–9.
11. Low DE, Desrosiers M, McSherry J et al. A practical guide for the diagnosis and treatment of acute sinusitis. CMAJ 1997; 156 (Suppl. 6): 1–14.
12. Farrell DJ, Klugman KP, Pichichero M. Increased antimicrobial resistance among nonvaccine serotypes of Streptococcus pneumoniae in the pediatric population after the introduction of 7-valent pneumococcal vaccine in the United States. Pediatr Infect Dis 2007; 26 (2): 123–8.
13. McLinn SE: Randomized, open label, multicenter trial of cefixime compared with amoxicillin for treatment of acute otitis media with effusion. Pediatr Infect Dis J 1987; 6: 997–1001.
14. Owen MJ, Anwar R, Nguyen HK et al. Efficacy of efixime in the treatment of acute otitis media in children. Am J Dis Child 1993; 147: 81–6.
15. Johnson CE, Carlin SA, Super DM et al. Cefixime compared with amoxicillin for treatment of acute otitis media. J Pediatr 1991; 119: 117–22.
16. Jansen WTM, Verel A, Beitsma M et al. Longitudinal European surveillance study of antibiotic resistance of Haemophilus influenza. J Antimicrob Chemother 2006; 58: 873–7.
17. Hausen Th, Weidlich G, Schmitt J. Safety and efficacy of cefixime in the treatment of respiratory tract infections in Germany. Infection 1995; 23 (Suppl. 2): 65–9.
18. DeMuri GP, Gern JE, Moyer SC et al. Clinical features, virus identification, and sinusitis as a complication of upper respiratory tract illness in children ages 4–7 years. J Pediatr 2016; 171: 133–9.
19. Hickner JM, Bartlett JG, Besser RE et al. Principles of appropriate antibiotic use for acute rhinosinusitis in adults: background. Ann Intern Med 2001; 134: 498–505.
20. Rosenfeld RM, Piccirillo JF, Chandrasekhar SS et al. Clinical practice guideline (update): adult sinusitis. Otolaryngol Head Neck Surg 2015; 152: S1–39.
21. Hansen FS, Hoffmans R, Georgalas C, Fokkens WJ. Complications of acute rhinosinusitis in The Netherlands. Fam Pract 2012; 29: 147–53.
22. Bastier PL, Lechot A, Bordenave L et al. Nasal irrigation: from empiricism to evidence-based medicine. A review. Eur Ann Otorhinolaryngol Head Neck Dis 2015; 132: 281–5.
23. Gehanno P, Boucot I, Berche P, Uhlrich J. Clinical efficacy and tolerability of cefixime in the treatment of acute sinusitis. Drugs 1991; 42 (Suppl. 4): 19–24.
24. Matthews BL, Kohut RI, Edelstein DR et al. Evaluation of cefixime in the treatment of bacterial maxillary sinusitis. South Med J 1993; 86 (3): 329–33.
25. Radtsig E.Iu., Pivneva N.D., Kotova E.N. i dr. Effektivnost' peroral'nogo tsefalosporina III pokoleniia pri LOR-patologii u deteĭ. Lechashchiĭ vrach. 2014; 10: 52 [in Russian]
26. Ovchinnikov A.Iu., Ovcharenko S.I., Kolbanova I.G. Vliianie effektivnogo lecheniia bakterial'nogo rinosinusita na techenie soputstvuiushcheĭ bronkhial'noĭ astmy. Lechashchiĭ vrach. 2007; 8: 9–13. [in Russian]
27. Belov B.S. Tsefiksim v terapii bakterial'nykh infektsiĭ. RMZh. 2013; 3. [in Russian]
28. Paniakina M.A., Ovchinnikov A.Iu., Miroshnichenko N.A. O tselesoobraznosti primeneniia tsefiksima dlia lecheniia bol'nykh ostrym bakterial'nym rinosinusitom. Farmateka. 2013; 4. [in Russian]
29. Weber R. Pharyngitis. Prim Care 2014; 41: 91–8.
30. Windfuhr JP, Toepfner N, Steffen G et al. Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management. Eur Arch Otorhinol 2016; 273: 973–87.
31. Petersen I, Johnson AM, Islam A et al. Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice Research Database. BMJ 2007; 335: 982.
32. Spinks A, Glasziou PP, Del Mar CB. Antibiotics for sore throat. Cochrane Database Syst Rev 2013. CD000023.
33. Gerber MA, Baltimore RS, Eaton CB et al. Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific state ment from the American Heart Association Rheumatic Fever. Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics. Circulation 2009; 119: 1541–51.
34. Egorova O.A., Kozlov S.N. Tsefiksim v terapii infektsii LOR-organov u detei. Vopr. sovr. pediatrii. 2008; 7 (3): 52–7. [in Russian]
35. Casey J, Pichichero ME. Meta-analysis of cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis in children. Pediatrics 2004; 113 (4): 866–82.
Авторы
Г.С.Мальцева*
ФГБУ «Санкт-Петербургский научно-исследовательский институт уха, горла, носа и речи» Минздрава России. 190013, Россия, Санкт-Петербург, ул. Бронницкая, д. 9
*g.s.maltseva@gmail.com
Saint Petersburg Research Institute of Ear, Nose, Throat and Speech of the Ministry of Health of the Russian Federation. 190013, Russian Federation, Saint Petersburg, ul. Bronnitskaya, d. 9
*g.s.maltseva@gmail.com
ФГБУ «Санкт-Петербургский научно-исследовательский институт уха, горла, носа и речи» Минздрава России. 190013, Россия, Санкт-Петербург, ул. Бронницкая, д. 9
*g.s.maltseva@gmail.com
________________________________________________
Saint Petersburg Research Institute of Ear, Nose, Throat and Speech of the Ministry of Health of the Russian Federation. 190013, Russian Federation, Saint Petersburg, ul. Bronnitskaya, d. 9
*g.s.maltseva@gmail.com
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