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Сосудистые изменения в клинике розацеа
Сосудистые изменения в клинике розацеа
Соркина И.Л., Сакания Л.Р., Пирузян А.Л., Корсунская И.М. Сосудистые изменения в клинике розацеа. Дерматология (Прил. к журн. Consilium Medicum). 2018; 2: 8–10.
DOI: 10.26442/2414-3537_2018.2.8-10
DOI: 10.26442/2414-3537_2018.2.8-10
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Материалы доступны только для специалистов сферы здравоохранения. Авторизуйтесь или зарегистрируйтесь.
Аннотация
В работе приводятся данные о нарушении микроциркуляции при розацеа и его влиянии на течение заболевания. Рассмотрены разные терапевтические подходы к лечению розацеа с учетом сосудистых изменений. Описан собственный опыт применения ангиопротекторов в комплексной терапии данной дерматологической патологии.
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Полный текст
Список литературы
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3. Ryan T. The blood vessels of the skin. J Invest Dermatol 1976; 67: 110–8.
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12. Holmes AD, Steinhoff M. Integrative concepts of rosacea pathophysiology, clinical presentation and new therapeutics. Exp Dermatol 2017; 26: 659–67. DOI: 10.1111/exd.13143
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14. Two AM, Wu W, Gallo RL et al. Topical and systemic therapies in the treatment of rosacea. J Am Acad Dermatol 2015; 72: 761–70. DOI: 10.1016/j.jaad.2014.08.027
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16. Соркина И.Л. Рациональная фармакотерапия розацеа с учетом микроциркуляции кожи и микробного пейзажа. Автореф. дис. … канд. мед. наук. М., 2014. / Sorkina I.L. Ratsionalnaia farmakoterapiia rozatsea s uchetom mikrotsirkuliatsii kozhi i mikrobnogo peizazha. Avtoref. dis. … kand. med. nauk. M., 2014. [in Russian]
17. Sharma R, Manvi S. Calcium dobesilate in Dermatology. JMSCR 2017; 5 (10): 28738–42.
18. Allain H, Ramelet AA, Polard E, Bentué-Ferrer D. Safety of calcium dobesilate in chronic venous disease, diabetic retinopathy and haemorrhoids. Drug Saf 2004; 27: 649–60.
19. Angulo J, Peiró C, Romacho T et al. Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial proliferation, arterial relaxation, vascular permeability and angiogenesis by dobesilate. Eur J Pharmacol 2011; 667 (1–3): 153 9. https://doi.org/10.1016/ j.ejphar.2011.06.015
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21. Инструкция по медицинскому применению Докси-Хем от 25.07.2017. https://www.stada.ru/products/doksi-hem.html / Instrukciya po medicinskomu primeneniyu Doksi-Hem ot 25.07.2017. https://www.stada.ru/products/doksi-hem.html [in Russian]
2. Burnstock G. Fine structural identification of autonomic nerves and their relation to smooth muscle. Prog Brain Res 1971; 34: 389–404.
3. Ryan T. The blood vessels of the skin. J Invest Dermatol 1976; 67: 110–8.
4. Smith JR, Lanier VB, Braziel RM et al. Expression of vascular endothelial growth factor and its receptors in rosacea. Br J Ophtalmol 2007; 91: 226–9.
5. Wollina U. Rhinophyma – unusual expression of simple-type keratins and S100A in sebocytes and abundance of VIP receptor-positive dermal cells. Histol Histopathol 1996; 11: 111–5.
6. Lange D, Funa K, Ishisaki A et al. Autocrine endothelial regulation in brain stem vessels of newborn piglets. Histol Histopathol 1999; 14: 821–5.
7. Potekaev N.N., Araviiskaia E.R., Sokolovskii E.V. i dr. Akne i rozatsea: monografiia. M.: Binom, 2007. [in Russian]
8. Pankina E.S. Narusheniia mikrotsirkuliatsii kozhi litsa pri rozatsea i metody ikh korrektsii. Avtoref. dis. … kand. med. nauk. SPb., 2008. [in Russian]
9. Fonseca GP, Brenner FM, Muller CS et al. Nailford capillaroscopy as a diagnostic and prognostic method in rosacea. An Bras Dermatol 2011; 86 (1): 87–90.
10. Rosina P, Zamperetti MR, Giovanni A et al. Videocapllaroscopic alterations in erhytematoteleangiectatic rosacea. J Am Acad Dermatol 2005; 54: 100–4.
11. Tsiskarishvili NV, Katsitadze A, Tsiskarishvili Ts et al. Angioprotectors in the treatment of rosacea. Georgian Med News 2014; 228: 251–4.
12. Holmes AD, Steinhoff M. Integrative concepts of rosacea pathophysiology, clinical presentation and new therapeutics. Exp Dermatol 2017; 26: 659–67. DOI: 10.1111/exd.13143
13. Steinhoff M, Shmelz M, Shauber J. Facial erythema of rosacea – aethiology, different pathophysiologies and treatment options. Acta Derm Venereol 2016; 96: 579–86. DOI: 10.2340/00015552335
14. Two AM, Wu W, Gallo RL et al. Topical and systemic therapies in the treatment of rosacea. J Am Acad Dermatol 2015; 72: 761–70. DOI: 10.1016/j.jaad.2014.08.027
15. Pavlov S.T., Shaposhnikov O.K., Samtsov V.I., Ilin I.I. Kozhnye i venericheskie bolezni. 3-e izd. M.: Meditsina, 1975; s. 234–44. [in Russian]
16. Sorkina I.L. Ratsionalnaia farmakoterapiia rozatsea s uchetom mikrotsirkuliatsii kozhi i mikrobnogo peizazha. Avtoref. dis. … kand. med. nauk. M., 2014. [in Russian]
17. Sharma R, Manvi S. Calcium dobesilate in Dermatology. JMSCR 2017; 5 (10): 28738–42.
18. Allain H, Ramelet AA, Polard E, Bentué-Ferrer D. Safety of calcium dobesilate in chronic venous disease, diabetic retinopathy and haemorrhoids. Drug Saf 2004; 27: 649–60.
19. Angulo J, Peiró C, Romacho T et al. Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial proliferation, arterial relaxation, vascular permeability and angiogenesis by dobesilate. Eur J Pharmacol 2011; 667 (1–3): 153–9. https://doi.org/10.1016/ j.ejphar.2011.06.015
20. Cuevas P, Arrazola JM. Therapeutic response of rosacea to dobesilate. Eur J Med Res 2005; 10 (10): 454–6.
21. Instrukciya po medicinskomu primeneniyu Doksi-Hem ot 25.07.2017. https://www.stada.ru/products/doksi-hem.html [in Russian]
2. Burnstock G. Fine structural identification of autonomic nerves and their relation to smooth muscle. Prog Brain Res 1971; 34: 389–404.
3. Ryan T. The blood vessels of the skin. J Invest Dermatol 1976; 67: 110–8.
4. Smith JR, Lanier VB, Braziel RM et al. Expression of vascular endothelial growth factor and its receptors in rosacea. Br J Ophtalmol 2007; 91: 226–9.
5. Wollina U. Rhinophyma – unusual expression of simple-type keratins and S100A in sebocytes and abundance of VIP receptor-positive dermal cells. Histol Histopathol 1996; 11: 111–5.
6. Lange D, Funa K, Ishisaki A et al. Autocrine endothelial regulation in brain stem vessels of newborn piglets. Histol Histopathol 1999; 14: 821–5.
7. Потекаев Н.Н., Аравийская Е.Р., Соколовский Е.В. и др. Акне и розацеа: монография. М.: Бином, 2007. / Potekaev N.N., Araviiskaia E.R., Sokolovskii E.V. i dr. Akne i rozatsea: monografiia. M.: Binom, 2007. [in Russian]
8. Панкина Е.С. Нарушения микроциркуляции кожи лица при розацеа и методы их коррекции. Автореф. дис. … канд. мед. наук. СПб., 2008. / Pankina E.S. Narusheniia mikrotsirkuliatsii kozhi litsa pri rozatsea i metody ikh korrektsii. Avtoref. dis. … kand. med. nauk. SPb., 2008. [in Russian]
9. Fonseca GP, Brenner FM, Muller CS et al. Nailford capillaroscopy as a diagnostic and prognostic method in rosacea. An Bras Dermatol 2011; 86 (1): 87–90.
10. Rosina P, Zamperetti MR, Giovanni A et al. Videocapllaroscopic alterations in erhytematoteleangiectatic rosacea. J Am Acad Dermatol 2005; 54: 100–4.
11. Tsiskarishvili NV, Katsitadze A, Tsiskarishvili Ts et al. Angioprotectors in the treatment of rosacea. Georgian Med News 2014; 228: 251–4.
12. Holmes AD, Steinhoff M. Integrative concepts of rosacea pathophysiology, clinical presentation and new therapeutics. Exp Dermatol 2017; 26: 659–67. DOI: 10.1111/exd.13143
13. Steinhoff M, Shmelz M, Shauber J. Facial erythema of rosacea – aethiology, different pathophysiologies and treatment options. Acta Derm Venereol 2016; 96: 579–86. DOI: 10.2340/00015552335
14. Two AM, Wu W, Gallo RL et al. Topical and systemic therapies in the treatment of rosacea. J Am Acad Dermatol 2015; 72: 761–70. DOI: 10.1016/j.jaad.2014.08.027
15. Павлов С.Т., Шапошников О.К., Самцов В.И., Ильин И.И. Кожные и венерические болезни. 3-е изд. М.: Медицина, 1975; с. 234–44. / Pavlov S.T., Shaposhnikov O.K., Samtsov V.I., Ilin I.I. Kozhnye i venericheskie bolezni. 3-e izd. M.: Meditsina, 1975; s. 234–44. [in Russian]
16. Соркина И.Л. Рациональная фармакотерапия розацеа с учетом микроциркуляции кожи и микробного пейзажа. Автореф. дис. … канд. мед. наук. М., 2014. / Sorkina I.L. Ratsionalnaia farmakoterapiia rozatsea s uchetom mikrotsirkuliatsii kozhi i mikrobnogo peizazha. Avtoref. dis. … kand. med. nauk. M., 2014. [in Russian]
17. Sharma R, Manvi S. Calcium dobesilate in Dermatology. JMSCR 2017; 5 (10): 28738–42.
18. Allain H, Ramelet AA, Polard E, Bentué-Ferrer D. Safety of calcium dobesilate in chronic venous disease, diabetic retinopathy and haemorrhoids. Drug Saf 2004; 27: 649–60.
19. Angulo J, Peiró C, Romacho T et al. Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial proliferation, arterial relaxation, vascular permeability and angiogenesis by dobesilate. Eur J Pharmacol 2011; 667 (1–3): 153 9. https://doi.org/10.1016/ j.ejphar.2011.06.015
20. Cuevas P, Arrazola JM. Therapeutic response of rosacea to dobesilate. Eur J Med Res 2005; 10 (10): 454–6.
21. Инструкция по медицинскому применению Докси-Хем от 25.07.2017. https://www.stada.ru/products/doksi-hem.html / Instrukciya po medicinskomu primeneniyu Doksi-Hem ot 25.07.2017. https://www.stada.ru/products/doksi-hem.html [in Russian]
________________________________________________
2. Burnstock G. Fine structural identification of autonomic nerves and their relation to smooth muscle. Prog Brain Res 1971; 34: 389–404.
3. Ryan T. The blood vessels of the skin. J Invest Dermatol 1976; 67: 110–8.
4. Smith JR, Lanier VB, Braziel RM et al. Expression of vascular endothelial growth factor and its receptors in rosacea. Br J Ophtalmol 2007; 91: 226–9.
5. Wollina U. Rhinophyma – unusual expression of simple-type keratins and S100A in sebocytes and abundance of VIP receptor-positive dermal cells. Histol Histopathol 1996; 11: 111–5.
6. Lange D, Funa K, Ishisaki A et al. Autocrine endothelial regulation in brain stem vessels of newborn piglets. Histol Histopathol 1999; 14: 821–5.
7. Potekaev N.N., Araviiskaia E.R., Sokolovskii E.V. i dr. Akne i rozatsea: monografiia. M.: Binom, 2007. [in Russian]
8. Pankina E.S. Narusheniia mikrotsirkuliatsii kozhi litsa pri rozatsea i metody ikh korrektsii. Avtoref. dis. … kand. med. nauk. SPb., 2008. [in Russian]
9. Fonseca GP, Brenner FM, Muller CS et al. Nailford capillaroscopy as a diagnostic and prognostic method in rosacea. An Bras Dermatol 2011; 86 (1): 87–90.
10. Rosina P, Zamperetti MR, Giovanni A et al. Videocapllaroscopic alterations in erhytematoteleangiectatic rosacea. J Am Acad Dermatol 2005; 54: 100–4.
11. Tsiskarishvili NV, Katsitadze A, Tsiskarishvili Ts et al. Angioprotectors in the treatment of rosacea. Georgian Med News 2014; 228: 251–4.
12. Holmes AD, Steinhoff M. Integrative concepts of rosacea pathophysiology, clinical presentation and new therapeutics. Exp Dermatol 2017; 26: 659–67. DOI: 10.1111/exd.13143
13. Steinhoff M, Shmelz M, Shauber J. Facial erythema of rosacea – aethiology, different pathophysiologies and treatment options. Acta Derm Venereol 2016; 96: 579–86. DOI: 10.2340/00015552335
14. Two AM, Wu W, Gallo RL et al. Topical and systemic therapies in the treatment of rosacea. J Am Acad Dermatol 2015; 72: 761–70. DOI: 10.1016/j.jaad.2014.08.027
15. Pavlov S.T., Shaposhnikov O.K., Samtsov V.I., Ilin I.I. Kozhnye i venericheskie bolezni. 3-e izd. M.: Meditsina, 1975; s. 234–44. [in Russian]
16. Sorkina I.L. Ratsionalnaia farmakoterapiia rozatsea s uchetom mikrotsirkuliatsii kozhi i mikrobnogo peizazha. Avtoref. dis. … kand. med. nauk. M., 2014. [in Russian]
17. Sharma R, Manvi S. Calcium dobesilate in Dermatology. JMSCR 2017; 5 (10): 28738–42.
18. Allain H, Ramelet AA, Polard E, Bentué-Ferrer D. Safety of calcium dobesilate in chronic venous disease, diabetic retinopathy and haemorrhoids. Drug Saf 2004; 27: 649–60.
19. Angulo J, Peiró C, Romacho T et al. Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial proliferation, arterial relaxation, vascular permeability and angiogenesis by dobesilate. Eur J Pharmacol 2011; 667 (1–3): 153–9. https://doi.org/10.1016/ j.ejphar.2011.06.015
20. Cuevas P, Arrazola JM. Therapeutic response of rosacea to dobesilate. Eur J Med Res 2005; 10 (10): 454–6.
21. Instrukciya po medicinskomu primeneniyu Doksi-Hem ot 25.07.2017. https://www.stada.ru/products/doksi-hem.html [in Russian]
Авторы
И.Л.Соркина1, Л.Р.Сакания2,3, А.Л.Пирузян3, И.М.Корсунская*3
1. АО «Клиника К+31». 119415, Россия, Москва,
ул. Лобачевского, д. 42, стр. 4;
2. ГБУЗ «Московский научно-практический центр дерматовенерологии и косметологии» Департамента здравоохранения г. Москвы. 119071, Россия, Москва, Ленинский пр-т, д. 17;
3. ФГБУН «Центр теоретических проблем физико-химической фармакологии» РАН. 119991, Россия, Москва, Ленинский пр-т, д. 38а, корп. 1
*marykor@bk.ru
1. “Clinic K+31”. 119415, Russian Federation, Moscow, ul. Lobachevskogo, d. 42, str. 4;
2. Moscow Scientific and Practical Center of Dermatology and Venereology and Cosmetology of the Department of Health of Moscow. 119071, Russian Federation, Moscow, Leninskiy pr-t, d. 17;
3. Center for Theoretical Problems of Physicochemical Pharmacology of the Russian Academy of Sciences. 119991, Russian Federation, Moscow, Leninskiy pr-t, d. 38a, korp. 1
*marykor@bk.ru
1. АО «Клиника К+31». 119415, Россия, Москва,
ул. Лобачевского, д. 42, стр. 4;
2. ГБУЗ «Московский научно-практический центр дерматовенерологии и косметологии» Департамента здравоохранения г. Москвы. 119071, Россия, Москва, Ленинский пр-т, д. 17;
3. ФГБУН «Центр теоретических проблем физико-химической фармакологии» РАН. 119991, Россия, Москва, Ленинский пр-т, д. 38а, корп. 1
*marykor@bk.ru
________________________________________________
1. “Clinic K+31”. 119415, Russian Federation, Moscow, ul. Lobachevskogo, d. 42, str. 4;
2. Moscow Scientific and Practical Center of Dermatology and Venereology and Cosmetology of the Department of Health of Moscow. 119071, Russian Federation, Moscow, Leninskiy pr-t, d. 17;
3. Center for Theoretical Problems of Physicochemical Pharmacology of the Russian Academy of Sciences. 119991, Russian Federation, Moscow, Leninskiy pr-t, d. 38a, korp. 1
*marykor@bk.ru
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