Висцеральный лейшманиоз у детей (собственные результаты и анализ литературы)

1. Aronson N, Copeland N, Magill A. Leishmania Species: Visceral (Kala-Azar), Cutaneous, and Mucosal Leishmaniasis. In: Benner J, Dolin R, Blaser M (Eds.) Mandell, ­Douglas and Bennett’s principles and practice of infectious diseases. 9th Ed. 2020; 3321–40.e4.
2. Заславский Д.В., Андриенко Е.М., Александрова И.Ю. и др. Верификация лейшманиоза кожи. Вестник дерматологии и венерологии. 2014; 5: 91–5. 
[Zaslavskii D.V., Andrienko E.M., Aleksandrova I.Iu. et al. Verification of cutaneous leishmaniasis. Vestnik dermatologii i venerologii. 2014; 5: 91–5 (in Russian).]
3. Hotez P, Lo N. Neglected tropical diseases: public health control programs and mass drug administration. In: Ryan E, Hill D, Solomin T et al. (Eds.) Hunter’s Tropical Medicine and Emerging Infectious Diseases. 2020. 10th Ed.; 209–13.
4. Garcia L. Leishmaniasis. In: Cherry J, Harrison G, Kaplan Sh et al. (Eds.) Feigin and cherry’s textbook of pediatric infectious diseases. 8th Ed. 2019; 2178–86.e2.
5. Leishmaniasis. 2014. http://www.who.int/topics/leishmaniasis/en/
6. Murray H, Berman J, Davies C et al. Advances in leishmaniasis. Lancet 2005; 366 (9496): 1561–77. 
7. Diagnosis and treatment of leishmaniasis: clinical practice guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH). Centers for Diseases Control and Prevention. https://www.cdc.gov/parasites/leishmaniasis/epi.html
8. Gradoni L. Leishmaniasis. In: Kellerman R, Rakel D (Eds.). Conn’s Current Therapy. 2020; 577–80.
9. De Menezes J, Koushik A, Das S et al. Leishmania infection inhibits macrophage motility by altering F-actin dynamics and the expression of adhesion complex proteins. Cell Microbiol 2017; 19 (3). DOI: 10.1111/cmi.12668
10. Ready P. Biology of phlebotomine sand flies as vectors of disease agents. An Rev ­Entomol 2013; 58: 227–50.
11. Pace D. Leishmaniasis. J Infect. 2014; 69; Suppl. 1: 10–8. DOI: 10.1016/j.jinf.2014.07.016
12. Hewitt S, Reyburn H, Ashford R, Rowland M. Anthroponotic cutaneous leishmaniasis in Kabul, Afghanistan: vertical distribution of cases in apartament blocks. Transact Royal Society Tropical Med Hyg 1998; 92 (3): 273–4.
13. World Health Organization (WHO). First WHO report on neglected tropical diseases 2010: working to overcome the global impact of neglected tropical diseases. Geneva, 2010.
14. Kevric I, Cappel M, Keeling J. New World and Old World Leishmania Infections. A Practical Review. Dermatol Clin 2015; 33 (3): 579–93.
15. Banuls A, Hide M, Pruqnolle F. Leishmania and the leishmaniases: a parasite genetic update and advances in taxonomy, epidemiology and pathogenicity in humans. Adv Parasitol 2007; 64: 1–109.
16. Chappuis F, Sundar S, Hailu A et al. Visceral leishmaniasis: what are the needs for diagnosis, treatment and control? Nat Rev Microbiol 2007; 5 (11): 873–82.
17. Sakthianandeswaren A, Foote S, Handman E. The role of host genetics in leishmaniasis. Trends Parasitol 2009; 25 (8): 383–91.
18. Zhang W, Matlashewski G. Characterization of the A2-A2rel gene cluster in Leishmania donovani: involvement of A2 in visceralization during infection. Mol Microbiol 2001; 39 (4): 935–48.
19. Okwor I, Uzonna J. Social and Economic Burden of Human Leishmaniasis. Am J Trop Med Hyg 2016; 94 (3): 489–93.

________________________________________________

1. Aronson N, Copeland N, Magill A. Leishmania Species: Visceral (Kala-Azar), Cutaneous, and Mucosal Leishmaniasis. In: Benner J, Dolin R, Blaser M (Eds.) Mandell, ­Douglas and Bennett’s principles and practice of infectious diseases. 9th Ed. 2020; 3321–40.e4.
2. Zaslavskii D.V., Andrienko E.M., Aleksandrova I.Iu. et al. Verification of cutaneous leishmaniasis. Vestnik dermatologii i venerologii. 2014; 5: 91–5 (in Russian).
3. Hotez P, Lo N. Neglected tropical diseases: public health control programs and mass drug administration. In: Ryan E, Hill D, Solomin T et al. (Eds.) Hunter’s Tropical Medicine and Emerging Infectious Diseases. 2020. 10th Ed.; 209–13.
4. Garcia L. Leishmaniasis. In: Cherry J, Harrison G, Kaplan Sh et al. (Eds.) Feigin and cherry’s textbook of pediatric infectious diseases. 8th Ed. 2019; 2178–86.e2.
5. Leishmaniasis. 2014. http://www.who.int/topics/leishmaniasis/en/
6. Murray H, Berman J, Davies C et al. Advances in leishmaniasis. Lancet 2005; 366 (9496): 1561–77. 
7. Diagnosis and treatment of leishmaniasis: clinical practice guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH). Centers for Diseases Control and Prevention. https://www.cdc.gov/parasites/leishmaniasis/epi.html
8. Gradoni L. Leishmaniasis. In: Kellerman R, Rakel D (Eds.). Conn’s Current Therapy. 2020; 577–80.
9. De Menezes J, Koushik A, Das S et al. Leishmania infection inhibits macrophage motility by altering F-actin dynamics and the expression of adhesion complex proteins. Cell Microbiol 2017; 19 (3). DOI: 10.1111/cmi.12668
10. Ready P. Biology of phlebotomine sand flies as vectors of disease agents. An Rev ­Entomol 2013; 58: 227–50.
11. Pace D. Leishmaniasis. J Infect. 2014; 69; Suppl. 1: 10–8. DOI: 10.1016/j.jinf.2014.07.016
12. Hewitt S, Reyburn H, Ashford R, Rowland M. Anthroponotic cutaneous leishmaniasis in Kabul, Afghanistan: vertical distribution of cases in apartament blocks. Transact Royal Society Tropical Med Hyg 1998; 92 (3): 273–4.
13. World Health Organization (WHO). First WHO report on neglected tropical diseases 2010: working to overcome the global impact of neglected tropical diseases. Geneva, 2010.
14. Kevric I, Cappel M, Keeling J. New World and Old World Leishmania Infections. A Practical Review. Dermatol Clin 2015; 33 (3): 579–93.
15. Banuls A, Hide M, Pruqnolle F. Leishmania and the leishmaniases: a parasite genetic update and advances in taxonomy, epidemiology and pathogenicity in humans. Adv Parasitol 2007; 64: 1–109.
16. Chappuis F, Sundar S, Hailu A et al. Visceral leishmaniasis: what are the needs for diagnosis, treatment and control? Nat Rev Microbiol 2007; 5 (11): 873–82.
17. Sakthianandeswaren A, Foote S, Handman E. The role of host genetics in leishmaniasis. Trends Parasitol 2009; 25 (8): 383–91.
18. Zhang W, Matlashewski G. Characterization of the A2-A2rel gene cluster in Leishmania donovani: involvement of A2 in visceralization during infection. Mol Microbiol 2001; 39 (4): 935–48.
19. Okwor I, Uzonna J. Social and Economic Burden of Human Leishmaniasis. Am J Trop Med Hyg 2016; 94 (3): 489–93.

Г.И. Волкова1,2, М.И. Смирнова1, В.М. Делягин*1

1 ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России, Москва, Россия;
2 Российская детская клиническая больница ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России
*delyagin-doktor@yandex.ru

________________________________________________

Galina I. Volkova1,2, Mariia I. Smirnova1, Wassili M. Delyagin*1

1 Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia;
2 Russian Children's Clinical Hospital, Pirogov Russian National Research Medical University, Moscow, Russia
*delyagin-doktor@yandex.ru